Results 231 to 240 of about 2,975,301 (351)

Molecular epidemiology of carbapenem-resistant hypervirulent <i>Klebsiella pneumoniae</i>: risk factors and resistance mechanism of ceftazidime/avibactam in China. [PDF]

Front Cell Infect Microbiol
Wang N, Deng L, Li H, Jia N, Peng X, Chang J, Hao J, Tang J, Lei C, Wang B, Liu J, Zhang W.   +11 more
europepmc   +1 more source

Regulatory mechanism of gravel cover on vegetation growth and erosion resistance performance of bank slopes in the Three Gorges Reservoir Area

Yuanyuan He, Xusheng Xia, Chenyu Zhang, Wenzhuo Hu   +3 more
openalex   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Editorial: Antibody-based novel target immunotherapy in hematological malignancy

Frontiers in Oncology
Weijie Cao, Yingmei Li, Haizhou Xing, Zhongxing Jiang, Jifeng Yu   +4 more
doaj   +1 more source

Preliminary Exploration of Fluvastatin Inhibiting Proliferation, Migration and Invasion of Lung Cancer Cells and Reversing Paclitaxel Resistance: Mechanism Exploration Based on Multi-Omics Analysis. [PDF]

Drug Des Devel Ther
Xu H, Du Z, Shui J, Li X, Tang J, Li G.
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

ETV6-NTRK3 as a resistance mechanism to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors: favorable response after combination of osimertinib and entrectinib: a case report and literature review. [PDF]

Front Pharmacol
Xie W, Luo H, Wang H, Shi G, Tang J, Ma L, Zhou J.   +6 more
europepmc   +1 more source

UNDERSTANDING THE CONCEPT OF PSEUDOMONAS AERUGINOSA BASIC RESISTANCE MECHANISMS AND IMPACT ON CYSTIC FIBROSIS PATIENTS

Ghaith R Mohammed
openalex   +2 more sources

Az általunk leírt általános növényi rezisztencia patológiai, biokémiai és molekuláris mechanizmusának további feltárása = Further investigation of the pathological, biochemical and molecular mechanisms of the general plant resistance described by our group [PDF]

, 2009
Sándor Süle, E. Besenyei, Zoltán Bozsó, Arnold Czelleng, Péter G. Ott, Ágnes Szatmári   +5 more
openalex  

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source