Results 81 to 90 of about 90,229,355 (301)

The Relationship between Type 2 Diabetes Mellitus and Related Thyroid Diseases

Journal of Diabetes Research, 2013
Type 2 diabetes mellitus (T2DM) has an intersecting underlying pathology with thyroid dysfunction. The literature is punctuated with evidence indicating a contribution of abnormalities of thyroid hormones to type 2 DM. The most probable mechanism leading
Chaoxun Wang
doaj   +1 more source

Psychological well-being on thyroid hormone replacement [PDF]

Despite 100 years after the discovery of thyroxine, controversy still exists regarding optimal thyroid hormone replacement therapy. Several anecdotal reports suggest that thyroxine alone therapy does not normalise psychological wellbeing.
Saravanan, Ponnusamy
core  

DNA-based diagnosis of thyroid hormone resistance syndrome: A novel THRB mutation associated with mild resistance to thyroid hormone

, 2005
Background: Thyroid hormones govern a wide range of metabolic processes in the body via thyroid hormone receptors (TR). We report a patient with mild resistance to thyroid hormone who was initially misdiagnosed and treated as having thyrotoxicosis ...
Tong, SF, Lam, CW, Shek, CC, Chan, AOK, Sau, CT   +4 more
core   +1 more source

Atrial Fibrillation with Heart Failure in a Case with Resistance to Thyroid Hormone Due to a Rare Thyroid Hormone Receptor β Gene Mutation

, 2022
Resistance to thyroid hormone (RTH) is a rare disease typically associated with elevated levels of thyroid hormones and non-suppressed thyroid stimulating hormones. The most common cause of RTH is thyroid hormone receptor β (THRβ) gene mutation.
Huei-Pin Lai, Lai, Huei-Pin, Chen, Mei-Hsiu, Mei-Hsiu Chen   +3 more
core   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Role of thyroid hormones in insulin resistance and diabetes

, 2015
: Several recent studies suggest that thyroid hormones role is not completely understood in insulin resistance as well as in the development of type 2 diabetes mellitus.
LULY, PAOLO, Davis, PJ, PEDERSEN, JENS ZACHO, CANDELOTTI, ELENA, Luly, P, De Vito, P, Ahmed, R.G., Pedersen, JZ, DE VITO, PAOLO, Candelotti, E, INCERPI, Sandra, Ahmed, RG, Incerpi, S   +12 more
core  

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

Chemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi, Alessandro Rubbi, Pablo A. Nogara, Giovanni Ribaudo, Vito Lippolis, João B. T. Rocha, Laura Orian   +6 more
wiley   +1 more source

Sensitivity to thyroid hormones in Egyptian euthyroid patients with metabolic syndrome

The Egyptian Journal of Internal Medicine
Background Metabolic syndrome (MetS) is a common metabolic and endocrine disease, and many studies have found that thyroid disorders, both overt and subclinical, might be accompanied by the risk of MetS. Objectives Assessment of indices of sensitivity to
Heba Ibrahim Selim, Fayez Elkenawy Mohammad, Mohammed Ibrahim Abd El-Ghany   +2 more
doaj   +1 more source

Levodopa induces thyroid function regulation in a patient with thyroid hormone resistance and Parkinson’s disease: a case report

Frontiers in Endocrinology
IntroductionThyroid hormone resistance (THR) is a rare genetic syndrome characterized by reduced sensitivity to thyroid hormones. Patients may be asymptomatic, although clinical manifestations depend on the THR subtype.
Gabriela Rozo-Paz, Clara Maria Ruiz-Forero, José David Suárez-Mera, Guillermo Monsalve Duarte, William Kattah Calderón   +4 more
doaj   +1 more source