Results 91 to 100 of about 485,715 (313)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Antibiotic resistance and heavy metal tolerance plasmids: the antimicrobial bulletproof properties of Escherichia fergusonii isolated from poultry

, 2019
Renata Galetti,1 Rafael Antonio Casarin Penha Filho,2 Joseane Cristina Ferreira,1 Alessandro M Varani,2 Ana Lúcia Costa Darini11Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeir ...
Penha Filho RAC, Ferreira JC, Darini ALC, Galetti R, Varani AM   +4 more
core  

Antibiotic resistance gene abundances correlate with metal and geochemical conditions in Scottish soils [PDF]

, 2011
The vast majority of antibiotic resistant genes (ARG) acquired by human pathogens have originated from the natural environment. Therefore, understanding factors that influence intrinsic levels of ARG in the environment could be epidemiologically ...
Brajesh K Singh, Seánı́n M. Mccluskey, Seánín M. McCluskey, Colin D Campbell, David W. Graham, Charles W. Knapp, Hudson, Gordon, Charles W Knapp, Gordon Hudson, David W Graham, Seánín M McCluskey, McCluskey, Seánín M., Campbell, Colin D., Graham, David W., Knapp, Charles W., Singh, Brajesh K., Brajesh K. Singh, Colin D. Campbell   +17 more
core   +1 more source

Amphibian infection tolerance to chytridiomycosis

, 2023
Animal defences against infection involve two distinct but complementary mechanisms: tolerance and resistance. Tolerance measures the animal's ability to limit detrimental effects from a given infection, whereas resistance is the ability to limit the ...
Laura F. Grogan, McCallum, Hamish I, Hamish I. McCallum, Madelyn J. Mangan, Mangan, Madelyn J, Grogan, Laura F   +5 more
core   +1 more source

Corrigendum: Identification and validation of Quantitative Trait Loci for Wheat dwarf virus resistance in wheat (Triticum spp.)

Frontiers in Plant Science, 2022
Anne-Kathrin Pfrieme, Britta Ruckwied, Antje Habekuß, Torsten Will, Andreas Stahl, Klaus Pillen, Frank Ordon   +6 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Fungal biofilm resistance [PDF]

, 2012
Fungal biofilm infections have become increasingly recognised as a significant clinical problem. One of the major reasons behind this is the impact that these have upon treatment, as antifungal therapy often fails and surgical intervention is required ...
Ramage, Gordon, Williams, Craig, Rajendran, Ranjith, Ranjith Rajendran, Gordon Ramage, Leighann Sherry, Sherry, Leighann, Craig Williams   +7 more
core   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Suitability of drought tolerance indices for selecting alfalfa (Medicago sativa L.) genotypes under organic farming in Austria

, 2012
In eastern Austria, alfalfa is usually grown as a rainfed crop in crop rotations in organic farming systems, where year-to-year rainfall fluctuations cause different levels of drought stress. To identify the suitability of different alfalfa genotypes and
Pietsch, Gabriele, Moghaddam, Ali, Vollmann, Johann, Wanek, Wolfgang, Friedel, Juergen K., Raza, Amir, Ardakani, M. Reza   +6 more
core  

A metabolic perspective into antimicrobial tolerance and resistance [PDF]

The Lancet Microbe, 2022
Ram Prasad Bhusal, Jeremy J Barr, Dinesh Subedi   +2 more
openaire   +3 more sources