Results 71 to 80 of about 485,715 (313)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Seedling salt tolerance in tomato

, 2011
Soils with higher concentrations of salt are becoming more and more a constraint for many crops to obtain high yields. Wild tomato species, adapted to adverse environments, are a potential reservoir for genes underlying quantitative trait loci (QTL ...
Visser, R.G.F., Du, Y., Liu, L., Zhang, Pujuan, van Heusden, A.W., Finkers, H.J., Heusden, A.W., van, Junming Li, J., Bai, Y.   +8 more
core   +1 more source

Veritas temporis filia est: Truth is the daughter of time [PDF]

Selekcija i Semenarstvo, 2016
In 1865, Gregor Mendel presented the lectures 'Experiments in Plant Hybridization' concerning his results from cross-breeding experiments with different types of garden pea, performed in his monastery garden in Brno.
Pržulj Novo, Perović Dragan, Mirosavljević Milan, Nožinić Miloš   +3 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Phosphaphenanthrene-modified zirconium phosphate nanosheets for improving fire resistance, smoke suppression and water tolerance of intumescent coatings

, 2023
Developing intumescent fire-retardant coatings (IFRCs) combining superior smoke suppression and water resistance is crucial for their industrial applications.
Cheng Wang, Fang, Zhengping, Ye, Guofeng, Guofeng Ye, Zhengping Fang, Wang, Cheng, Siqi Huo, Hao Wang, Liu, Zhitian, Zhitian Liu, Huo, Siqi, Wang, Hao   +11 more
core   +1 more source

Prediction of Means and Variances of Crosses With Genome-Wide Marker Effects in Barley

Frontiers in Plant Science, 2018
Background: The expected genetic variance is an important criterion for the selection of crossing partners which will produce superior combinations of genotypes in their progeny.
Tanja Osthushenrich, Matthias Frisch, Carola Zenke-Philippi, Heidi Jaiser, Monika Spiller, László Cselényi, Kerstin Krumnacker, Susanna Boxberger, Doris Kopahnke, Antje Habekuß, Frank Ordon, Eva Herzog   +11 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

A facile strategy to fabricate an intumescent fire-retardant coating with improved fire resistance and water tolerance for steel structure

, 2020
An intumescent fire-retardant coating (IFRC) with improved fire resistance and water tolerance was prepared in this work, resulting from the introduction of microcapsuled ammonium polyphosphate (MFAPP) and zinc borate (MFBZ).
Liu, Shi, Zhang, Qi, Wang, Cheng, Liu, Zhitian, Hu, Qinghua, Huo, Siqi   +5 more
core   +1 more source

Resistance, Obedience and Toleration: Przypkowski and Limborch

, 2005
The interesting, albeit scanty, correspondence between Wiszowaty and Limborch extended over a span of more than twenty years - from 1682 to 1704 - touching on various theological and exegetic questions: from the theme of marriage and adultery to the that of the Holy Supper.
openaire   +4 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source