Results 91 to 100 of about 8,220,337 (334)

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Skeletal muscle myosin heavy chain fragmentation as a potential marker of protein degradation in response to resistance training and disuse atrophy

Experimental Physiology
We examined how resistance exercise (RE), cycling exercise and disuse atrophy affect myosin heavy chain (MyHC) protein fragmentation. The 1boutRE study involved younger men (n = 8; 5 ± 2 years of RE experience) performing a lower body RE bout with vastus
Daniel L. Plotkin, Madison L. Mattingly, Derick A. Anglin, J. Max Michel, Joshua S. Godwin, Mason C. McIntosh, Nicholas J. Kontos, João G. A. Bergamasco, Maíra C. Scarpelli, Vitor Angleri, Lemuel W. Taylor, Darryn S. Willoughby, C. Brooks Mobley, Andreas N. Kavazis, Carlos Ugrinowitsch, Cleiton A. Libardi, Michael D. Roberts   +16 more
doaj   +1 more source

Genotypic characterization of extended-spectrum beta-lactamase-producing E. coli from dogs in northern Germany

Microbiology Spectrum
Antimicrobial resistance (AMR) is a growing concern in veterinary and public health, with extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli playing a significant role.
Marco Werhahn Beining, Sebastian Guenther, Antina Lüebke-Becker, Stefan E. Heiden, Katharina Schaufler, Lothar Kreienbrock, Michael Schwabe   +6 more
doaj   +1 more source

Beware the Meta-Analysis: Is Multiple Set Training Really Better than Single-Set Training for Muscle Hypertrophy? [PDF]

, 2012
While many individuals perform resistance training with the purpose of increasing the size of their muscles, reviews have not clarified a training prescription for optimizing hypertrophy. A 2010 meta-analysis concluded that multiple set training resulted
Fisher, James
core   +1 more source

Impact of Endurance and Resistance Training on Skeletal Muscle Glucose Metabolism in Older Adults

Nutrients, 2019
Aging is associated with insulin resistance and the development of type 2 diabetes. While this process is multifaceted, age-related changes to skeletal muscle are expected to contribute to impaired glucose metabolism.
L. Consitt, Courtney Dudley, G. Saxena
semanticscholar   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Effects of variable resistance training with different load ratios on lower-limb strength and power in male college students

Journal of Exercise Science & Fitness
Objective: The optimum relationship combination of variable to constant resistance within variable resistance training (VRT) for enhancing lower-limb strength and power remains unclear.
Changbo Pan, Wei Li, Yuying Su, Yu Shi
doaj   +1 more source

Using Swing Resistance and Assistance to Improve Gait Symmetry in Individuals Post-Stroke [PDF]

, 2015
A major characteristic of hemiplegic gait observed in individuals post-stroke is spatial and temporal asymmetry, which may increase energy expenditure and the risk of falls.
Schmit, Brian D., Wu, Ming, Yen, Sheng-Che   +2 more
core   +2 more sources

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Initial neuromuscular performance in older women influences response to explosive resistance training [PDF]

, 2009
The purpose of the study was to identify both demographic and neuromuscular traits that characterize successful or unsuccessful adaptation to resistance training in older women.
LaRoche, Dain P.
core   +1 more source