Results 11 to 20 of about 1,598,652 (266)
Resistance-resistant antibiotics [PDF]
Trends in Pharmacological Sciences, 2014 New antibiotics are needed because drug resistance is increasing while the introduction of new antibiotics is decreasing. We discuss here six possible approaches to develop 'resistance-resistant' antibiotics. First, multitarget inhibitors in which a single compound inhibits more than one target may be easier to develop than conventional combination ...
Eric, Oldfield, Xinxin, Feng
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Resistance to “Castration-Resistant” [PDF]
The Oncologist, 2014 The author challenges the use of the phrase “castration resistance,” which is widely used in the literature and also appears in a recent article by Merseburger et al.
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Hereditas, 2022 Purpose To explore the role and effects of the single-nucleotide polymorphisms (SNPs) of the two functionally related indoleamine 2,3-dioxygenase (IDO) isoforms on IDO activity in the Chinese Han ethnic population.
Tingming Cao +6 more
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Frontiers in Oncology, 2021 BackgroundHistological transformation of lung cancer to small cell lung cancer (SCLC) is uncommon. It is a small subset of the possible resistance mechanisms, even in epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer treated with
Qian Shen +4 more
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Annual Review of Cancer Biology, 2017 Targeted therapies, immunotherapies, and improved chemotherapies are being developed to reduce the suffering and mortality that come from human cancer. Although these approaches, and in particular combinations of them, are expected to succeed eventually to a large degree, they all suffer one obstacle: Populations of replicating cells move away ...
Ivana Bozic, Martin A. Nowak
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Resisting Potato Cyst Nematodes With Resistance [PDF]
Frontiers in Plant Science, 2021 Potato cyst nematodes (PCN) are economically important pests with a worldwide distribution in all temperate regions where potatoes are grown. Because above ground symptoms are non-specific, and detection of cysts in the soil is determined by the intensity of sampling, infestations are frequently spread before they are recognised.
Ulrike Gartner +14 more
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High prevalence of itraconazole resistance among Candida parapsilosis isolated from Iran [PDF]
Current Medical Mycology, 2019 Background and Purpose: Candida parapsilosis isolates usually have a low minimum inhibitory concentration (MIC) against azoles. Although Candida parapsilosis isolates usually have low MICs against azoles, recent studies candida invasive infections due to
Fozieh Hassanmoghadam +8 more
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Materials Research LettersAg coatings by additive manufacturing are a representative high-performance electrical contact materials. Here, an appropriate current of 2 A is introduced during the friction process to optimize the current-carrying friction behavior and anti-wear ...
Jiebin Du +4 more
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Journal of Applied Botany and Food Quality, 2015 In the last decades procedures for obtaining protein isolates and concentrates derived from narrow-leafed lupins (L. angustifolius) for human nutrition have been developed.
Helene Beyer +4 more
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Insects, 2022 The aphid lion, Chrysoperla zastrowi sillemi (Neuroptera: Chrysopidae) is a highly effective beneficial predator of many agricultural pests and has developed resistance to several insecticides.
Jyoti Pathak +9 more
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