Results 21 to 30 of about 1,598,652 (266)

National retrospective study of regional prescriber-specific variation in community antibiotic prescribing Canada, 2019–2023

BMJ Public Health
Background Antimicrobial resistance (AMR) is a growing public health challenge in Canada and globally, largely driven by unnecessary or suboptimal antimicrobial use (AMU).
Kahina Abdesselam, Drew Greydanus, Pia Kaur Muchaal, Sakhi Mittal, Raymond-Jonas Ngendabanka, Kanchana Amaratunga, Aanchal Mishra, Tanya Lary   +7 more
doaj   +1 more source

Ascorbic acid promotes 3T3-L1 cells adipogenesis by attenuating ERK signaling to upregulate the collagen VI

Nutrition & Metabolism, 2017
Background Type VI collagen is supposed to be a regulation factor in adipogenesis. This study aimed to assess the promoting effect of vitamin C (VC) on adipogenic differentiation of preadipocytes as well as its mechanism.
Chuanguo Liu, Kun Huang, Guorong Li, Pingping Wang, Chang Liu, Congcong Guo, Zongguo Sun, Jie Pan   +7 more
doaj   +1 more source

Therapies for obsessive-compulsive disorder: Current state of the art and perspectives for approaching treatment-resistant patients

Frontiers in Psychiatry, 2023
Even though obsessive compulsive disorder (OCD) is one of the ten most disabling diseases according to the WHO, only 30–40% of patients suffering from OCD seek specialized treatment.
Kevin Swierkosz-Lenart, Joao Flores Alves Dos Santos, Julien Elowe, Julien Elowe, Anne-Hélène Clair, Julien F. Bally, Françoise Riquier, Jocelyne Bloch, Bogdan Draganski, Bogdan Draganski, Marie-Thérèse Clerc, Beatriz Pozuelo Moyano, Armin von Gunten, Luc Mallet, Luc Mallet, Luc Mallet   +15 more
doaj   +1 more source

Identification of Local Rice Genotypes from Deli Serdang, North Sumatera, Indonesia to Drought Stress Condition

Journal of Applied Agricultural Science and Technology, 2021
Regency of Deli Serdang in the Province of Sumatera Utara has high diversity of landrace rice that has adapted to various climatic and edaphic condition including drought.
Irawati Chaniago, Noverina Chaniago, Irfan Suliansyah, Nalwida Rozen   +3 more
doaj   +1 more source

The oxidation mechanisms of Pt and reactive elements modified AlCoCrFeNi2.1 eutectic high-entropy alloy at high temperature

Journal of Materials Research and Technology
AlCoCrFeNi2.1 eutectic high-entropy alloys (EHEAs) show great potential in high-temperature applications due to the dual-phase lamellar structure. In this work, the high-temperature oxidation behavior and scaling mechanisms of three AlCoCrFeNi2.1 EHEAs ...
Qinying Huang, Yuzhuo Li, Peng Zhang, Yingfei Yang, Shengfeng Zhou, Pan Ren, Qiwei Wang, Wei Li, Fuhui Wang   +8 more
doaj   +1 more source

Mechanistic insights into nanoparticle surface-bacterial membrane interactions in overcoming antibiotic resistance

Frontiers in Microbiology, 2023
Antimicrobial Resistance (AMR) raises a serious concern as it contributes to the global mortality by 5 million deaths per year. The overall impact pertaining to significant membrane changes, through broad spectrum drugs have rendered the bacteria ...
Suraj Kumar Modi, Suraj Kumar Modi, Smriti Gaur, Mrittika Sengupta, Mrittika Sengupta, Manu Smriti Singh, Manu Smriti Singh   +6 more
doaj   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Cinnamaldehyde supplementation in sows and their offspring: effects on colostrum and milk composition, performance, redox status and intestinal health

Journal of Animal Science and Biotechnology
Background Maternal nutrition significantly influences offspring development. This study investigated the effects of maternal or post-weaning cinnamaldehyde (CA) supplementation in sows and their offspring on reproductive performance and health.
Junqi Jin, Shiya Liu, Qiang Zhou, Zhengfeng Fang, Yan Lin, Shengyu Xu, Bin Feng, Yong Zhuo, Hefeng Luo, Xiuming Liu, De Wu, Lianqiang Che   +11 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen, Kristian Juul Sandahl, Lene Karlsson, Jonas Abrahamsson, Nira Arad‐Cohen, Daniel Cheuk, Barbara De Moerloose, Linda Fogelstrand, Jose Maria Fernandez Navarro, Bianca F. Goemans, Kirsi Jahnukainen, Gertjan Kaspers, Zhanna Kovalova, Monica Cheng Munthe‐Kaas, Ulrika Norén‐Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Tierens, Henrik Hasle, Kristian Løvvik Juul‐Dam   +21 more
wiley   +1 more source