Results 21 to 30 of about 3,703,855 (310)

High prevalence of itraconazole resistance among Candida parapsilosis isolated from Iran [PDF]

Current Medical Mycology, 2019
Background and Purpose: Candida parapsilosis isolates usually have a low minimum inhibitory concentration (MIC) against azoles. Although Candida parapsilosis isolates usually have low MICs against azoles, recent studies candida invasive infections due to
Fozieh Hassanmoghadam, Tahere Shokohi, Mohammad Taghi Hedayati, Narges Aslani, Iman Haghani, Mojtaba Nabili, Ensieh Lotfali, Amirhossein Davari, Maryam Moazeni   +8 more
doaj   +1 more source

Allosteric p97 inhibitors can overcome resistance to ATP-competitive p97 inhibitors for potential anti-cancer therapy [PDF]

, 2020
A major challenge of targeted cancer therapy is the selection for drug‐resistant mutations in tumor cells leading to loss of treatment effectiveness. p97/VCP is a central regulator of protein homeostasis and a promising anti‐cancer target because of its ...
Chou, Tsui-Fen, Flint, Andrew J., Gan, Taiping, Li, Shan, Stott, Gordon M., Wang, Feng   +5 more
core   +1 more source

Comparative Transcriptome Analysis to Reveal Differentially Expressed Cytochrome P450 in Response to Imidacloprid in the Aphid Lion, Chrysoperla zastrowi sillemi (Esben-Petersen)

Insects, 2022
The aphid lion, Chrysoperla zastrowi sillemi (Neuroptera: Chrysopidae) is a highly effective beneficial predator of many agricultural pests and has developed resistance to several insecticides.
Jyoti Pathak, Gandhi Gracy Ramasamy, Aditi Agrawal, Subhi Srivastava, Bhusangar Raghavendra Basavaarya, Mohan Muthugounder, Venugopal Kundalagurki Muniyappa, Pratheepa Maria, Anil Rai, Thiruvengadam Venkatesan   +9 more
doaj   +1 more source

Review of multidrug-resistant and extensively drug-resistant TB: global perspectives with a focus on sub-Saharan Africa [PDF]

, 2010
Tuberculosis (TB) remains a global emergency and is responsible for 1.7 million deaths annually. Widespread global misuse of isoniazid and rifampicin over three decades has resulted in emergence of the ominous spread of multidrug-resistant TB (MDR-TB ...
Abdool Karim, Amor, Balabanova, Caminero, Centers for Disease Control and Prevention, Chan, Chiang, Chiang, Chiang, Churchyard, Dheda, Dravniece, Dubrovina, Elliott, Espinal, Espinal, Espinal, Flament-Saillour, Gandhi, Gandhi, Gandhi, Goble, Grobusch, Habeenzu, Hoek, Holtz, Holtz, Iseman, Johnson, Kehinde, Kim, Kingkaew, Korenromp, Kranzer, Lalloo, Laserson, Lienhardt, Ma, Martin, Matteelli, Meskel, Migliori, Migliori, Migliori, Migliori, Migliori, Moore, Motus, O’Donnell, Pablos-Méndez, Pai, Park, Pietzka, Pillay, Quy, Saravia, Schaaf, Schaaf, Shah, Somocurcio, Sonnenberg, Sotgiu, Torun, Umubyeyi, Wallis, WHO, WHO, WHO and IUATLD, Wright, Wright, Zumla   +70 more
core   +1 more source

Therapies for obsessive-compulsive disorder: Current state of the art and perspectives for approaching treatment-resistant patients

Frontiers in Psychiatry, 2023
Even though obsessive compulsive disorder (OCD) is one of the ten most disabling diseases according to the WHO, only 30–40% of patients suffering from OCD seek specialized treatment.
Kevin Swierkosz-Lenart, Joao Flores Alves Dos Santos, Julien Elowe, Julien Elowe, Anne-Hélène Clair, Julien F. Bally, Françoise Riquier, Jocelyne Bloch, Bogdan Draganski, Bogdan Draganski, Marie-Thérèse Clerc, Beatriz Pozuelo Moyano, Armin von Gunten, Luc Mallet, Luc Mallet, Luc Mallet   +15 more
doaj   +1 more source

Increased expression of a microRNA correlates with anthelmintic resistance in parasitic nematodes [PDF]

, 2017
Resistance to anthelmintic drugs is a major problem in the global fight against parasitic nematodes infecting humans and animals. While previous studies have identified mutations in drug target genes in resistant parasites, changes in the expression ...
Bartley, David, Britton, Collette, Devaney, Eileen, Gillan, Victoria, Gilleard, John S., Gu, Henry, Laing, Roz, Maitland, Kirsty, Marks, Neil D., Martinelli, Axel, Morrison, Alison, Rezansoff, Andrew M., Skuce, Philip J., Winter, Alan D.   +13 more
core   +2 more sources

Identification of Local Rice Genotypes from Deli Serdang, North Sumatera, Indonesia to Drought Stress Condition

Journal of Applied Agricultural Science and Technology, 2021
Regency of Deli Serdang in the Province of Sumatera Utara has high diversity of landrace rice that has adapted to various climatic and edaphic condition including drought.
Irawati Chaniago, Noverina Chaniago, Irfan Suliansyah, Nalwida Rozen   +3 more
doaj   +1 more source

Heat resistant protective hand covering [PDF]

, 1984
A heat-resistant aromatic polyamide fiber is described. The outer surface of the shell is coated with a fire-resistant elastomer and liner. Generally conforming and secured to the shell and disposed inwardly of the shell, the liner is made of a felt ...
Arons, I. J., Sidman, K. R., Tschirch, R. P.   +2 more
core   +4 more sources

Current-carrying friction of Ag coatings by additive manufacturing: uncovering the role of electric current

Materials Research Letters
Ag coatings by additive manufacturing are a representative high-performance electrical contact materials. Here, an appropriate current of 2 A is introduced during the friction process to optimize the current-carrying friction behavior and anti-wear ...
Jiebin Du, Mingchong Lu, Jiamin Fang, Wei Li, Dexin Chen   +4 more
doaj   +1 more source