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Management of treatment resistance in schizophrenia

Biological Psychiatry, 2001
A systematic approach to the evaluation and characterization of treatment resistance in schizophrenia has become increasingly important since the introduction of the second-generation antipsychotics. The need for accurate evaluation will increase further as other new antipsychotic medications are developed. Patients with schizophrenia may manifest poor
R R, Conley, D L, Kelly
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Treatment-Resistant Schizophrenia

The Primary Care Companion For CNS Disorders
The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who ...
Carol S, Lim   +5 more
  +5 more sources

Insulin Resistance in Schizophrenia

2019
Schizophrenia and diabetes have been known to be linked disorders for decades. One reason is due to the fact that a major side effect of antipsychotic medication treatment is metabolic syndrome, which increases the risk of the patients developing type 2 diabetes and cardiovascular disorders.
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Schizophrenia resistance ( is there a difference?)

Egyptian Journal of Psychiatry, 2013
Background Schizophrenia is a chronic disease of the body and mind that affects 1% of the population. About one-fifth to one-third of all patients with schizophrenia do not respond adequately to drug treatment and that have been consistent over time.
Mamdoh ElGamal   +2 more
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An approach to treatment resistance in schizophrenia

British Journal of Psychiatry, 1999
Currently, patients with schizophrenia are usually considered refractory to treatment if they continue to be floridly symptomatic despite receiving treatment with conventional antipsychotic agents. Attempts to improve their response by increasing the dosage, adding supplementary drugs, or switching to agents of another class have not been very ...
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Treatment resistance in schizophrenia

Psychiatry, 2005
Abstract In a substantial proportion of people with schizophrenia the illness shows a poor response to antipsychotic medication. Failure to achieve remission even after the first episode is limited to relatively few cases, and more commonly patients become progressively unresponsive to medication.
Thomas R.E. Barnes, Serdar Dursun
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Treatment-Resistant Schizophrenia

2019
A significant minority of patients (about one quarter to one third) will have a poor response to first-line antipsychotics and be considered treatment-resistant. In this chapter, I outline a sequential approach to treatment-resistant schizophrenia.
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A case of resistant schizophrenia

2013
Bollettino della Società Medico Chirurgica di Pavia, Vol 126, N° 3 (2013)
Oliani, Daniela Maria   +4 more
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Managing resistant schizophrenia.

British journal of hospital medicine, 1994
Approximately 25% of patients with schizophrenia remain actively psychotic despite treatment with conventional antipsychotic medication. Many of these patients become new long-stay patients or are frequent readmissions to psychiatric hospitals. This article reviews some of the causes of treatment resistance and the management of this group of patients.
P L, Huckle, S S, Palia
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[Clozapine and resistant schizophrenia].

L'Encephale, 1990
Clozapine is an atypical antipsychotic drug, with distinguishing features from neuroleptics which are believed to exert their therapeutic effect by blocking dopamine receptors in the limbic system. Clozapine is both chemically and pharmacologically distinct from neuroleptics such as chlorpromazine and haloperidol.
J J, Pere, D, Chaumet-Riffaud
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