Results 1 to 10 of about 27,215 (156)

The Group of Treatment Resistant Schizophrenias. Heterogeneity in Treatment Resistant Schizophrenia (TRS) [PDF]

Frontiers in Psychiatry, 2019
Schizophrenia is composed of a heterogeneous group of patient segments. Our current notion of the heterogeneity in schizophrenia is based on patients presenting with diverse disease symptom phenotypes, risk factors, structural and functional ...
Bruce J. Kinon
doaj   +5 more sources

Treatment-resistant schizophrenia: How far have we traveled?

Frontiers in Psychiatry, 2022
Treatment-resistant schizophrenia is a lack of adequate response to antipsychotic medications resulting in incomplete functional and social recovery from the illness.
Ambu Pandey, Kamal Narayan Kalita
doaj   +3 more sources

Pharmacotherapy for treatment-resistant schizophrenia

Neuropsychiatric Disease and Treatment, 2011
Meghan E Mcilwain1,2, Jeff Harrison1, Amanda J Wheeler1,3, Bruce R Russell1,21School of Pharmacy, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand; 2Centre for Brain Research, Faculty of Medical and Health Sciences ...
Meghan E Mcilwain, Jeff Harrison, Amanda J Wheeler, et al   +3 more
doaj   +6 more sources

Distinct subcortical neuroanatomic profiles of treatment-resistant schizophrenia: structural magnetic resonance imaging study [PDF]

BJPsych Open
Background Understanding the neuroanatomical correlates of treatment response in schizophrenia is crucial for improving clinical stratification and clarifying underlying pathophysiological mechanisms.
Ibrahim Sungur, Simay Selek, Kaan Keskin, Asli Ceren Hinc, Furkan Yazici, Elif Ozge Aktas, Yigit Erdogan, Omer Kitis, Ali Saffet Gonul   +8 more
doaj   +2 more sources

Role of aripiprazole in treatment-resistant schizophrenia

Neuropsychiatric Disease and Treatment, 2012
Nilufar Mossaheb,1 Rainer M Kaufmann21Department of Child and Adolescent Psychiatry, 2Department of Psychiatry and Psychotherapy, Medical University, Vienna, AustriaAbstract: About one third of patients with schizophrenia respond unsatisfactorily to ...
Mossaheb N, Kaufmann RM
doaj   +5 more sources

Cariprazine: Patients with Treatment-Resistant Schizophrenia

Neuropsychiatric Disease and Treatment, 2021
Thomas Aubel Kliniken Essen-Mitte, Klinik für Psychiatrie, Psychotherapie, Psychosomatik und Suchtmedizin, Essen, GermanyCorrespondence: Thomas AubelKliniken Essen-Mitte, Klinik für Psychiatrie, Psychotherapie, Psychosomatik und Suchtmedizin ...
Aubel T
doaj   +4 more sources

Effectiveness of deep brain stimulation in alleviating treatment-resistant schizophrenia: a systematic review [PDF]

European Journal of Translational Myology
The complexity of schizophrenia, particularly in cases resistant to traditional pharmacological treatments, poses significant challenges for clinicians and researchers.
Mohsen Khosravi
doaj   +2 more sources

Potential efficacy of dopaminergic antidepressants in treatment resistant anergic-anhedonic depression results of the chronic anergic-anhedonic depression open trial – CADOT

Frontiers in Psychiatry, 2023
IntroductionAmong treatment-resistant depression (TRD), we identified anergic-anhedonic clinical presentations (TRAD) as putatively responsive to pro-dopaminergic strategies.
Ludovic Christophe Dormegny-Jeanjean, Ludovic Christophe Dormegny-Jeanjean, Ludovic Christophe Dormegny-Jeanjean, Clément de Billy, Clément de Billy, Clément de Billy, Olivier Mainberger, Olivier Mainberger, Olivier Mainberger, Sébastien Weibel, Sébastien Weibel, Sébastien Weibel, Benoit Schorr, Benoit Schorr, Benoit Schorr, Alexandre Obrecht, Alexandre Obrecht, Lionel Landré, Fabrice Berna, Fabrice Berna, Jean-Baptiste Causin, Jean-Baptiste Causin, Jean-Baptiste Causin, Frederic Blanc, Frederic Blanc, Vlad Danila, Vlad Danila, Mihaela Tomsa, Mihaela Tomsa, Geraldine Pfleger, Geraldine Pfleger, Camille Meyer, Camille Meyer, Camille Meyer, Ilia Humbert, Ilia Humbert, Ilia Humbert, Hervé Javelot, Hervé Javelot, Guillaume Meyer, Guillaume Meyer, Gilles Bertschy, Gilles Bertschy, Gilles Bertschy, Jack Rene Foucher, Jack Rene Foucher, Jack Rene Foucher, Jack Rene Foucher   +47 more
doaj   +1 more source

DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia

eLife, 2021
We performed a systematic analysis of blood DNA methylation profiles from 4483 participants from seven independent cohorts identifying differentially methylated positions (DMPs) associated with psychosis, schizophrenia, and treatment-resistant ...
Eilis Hannon, Emma L Dempster, Georgina Mansell, Joe Burrage, Nick Bass, Marc M Bohlken, Aiden Corvin, Charles J Curtis, David Dempster, Marta Di Forti, Timothy G Dinan, Gary Donohoe, Fiona Gaughran, Michael Gill, Amy Gillespie, Cerisse Gunasinghe, Hilleke E Hulshoff, Christina M Hultman, Viktoria Johansson, René S Kahn, Jaakko Kaprio, Gunter Kenis, Kaarina Kowalec, James MacCabe, Colm McDonald, Andrew McQuillin, Derek W Morris, Kieran C Murphy, Colette J Mustard, Igor Nenadic, Michael C O'Donovan, Diego Quattrone, Alexander L Richards, Bart PF Rutten, David St Clair, Sebastian Therman, Timothea Toulopoulou, Jim Van Os, John L Waddington, Wellcome Trust Case Control Consortium (WTCCC), CRESTAR consortium, Patrick Sullivan, Evangelos Vassos, Gerome Breen, David Andrew Collier, Robin M Murray, Leonard S Schalkwyk, Jonathan Mill   +47 more
doaj   +1 more source

Treatment resistance in schizophrenia [PDF]

BMJ, 1996
Alternative drugs may offer clearer understanding of underlying mechanisms Since the 1950s, when chlorpromazine was introduced into psychiatric practice, antipsychotic drugs have been the cornerstone of the management of schizophrenia. They have three main functions: to treat the positive symptoms of acute schizophrenic episodes; to reduce ...
E C, Johnstone, R, Sandler
openaire   +2 more sources