Results 31 to 40 of about 59,572 (271)

Is disorganized schizophrenia a predictor of treatment resistance? Evidence from an observational study

Brazilian Journal of Psychiatry, 2013
Objective: To investigate whether inpatients with disorganized schizophrenia are more resistant to treatment. Method: Eighty-five inpatients were assessed at admission and at discharge for schizophrenia subtype, symptom severity, and treatment ...
Bruno Bertolucci Ortiz, Gerardo Maria de Araújo Filho, Ary Gadelha de Alencar Araripe Neto, Daiane Medeiros, Rodrigo Affonseca Bressan   +4 more
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Combination of clozapine, cariprazine and fluoxetine in treatment-resistant schizophrenia patient with prominent negative symptoms: A Case report

European Psychiatry, 2022
Introduction Despite pharmacological advances in the treatment of schizophrenia, significant number of patients are still treatment-resistant. Clozapine is recommended as first-line treatment for treatment-resistant schizophrenia (TRS) in guidelines ...
I. Everte, A. Pamše-Romāne, M. Taube
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Strategies in clozapine-resistant schizophrenia: A literature review

Journal of Mental Health and Human Behaviour, 2016
Treatment resistance to what is often deemed the last line of schizophrenia treatment, clozapine, is a burgeoning problem in psychiatric practice, with estimates of clozapine resistance standing at 40–70% of the treated population.
Ganesh Kundadak Kudva, Dhanesh Kumar Gupta   +1 more
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Association of DRD2, DRD4 and COMT genes variants and their gene-gene interactions with antipsychotic treatment response in patients with schizophrenia

BMC Psychiatry, 2023
Antipsychotic drugs are the first line of treatment in schizophrenia; although antipsychotic responses indicate a wide interindividual variety in patients with schizophrenia.
Narges Taheri, Rokhshid Pirboveiri, Mehdi Sayyah, Mahdi Bijanzadeh, Pegah Ghandil   +4 more
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Lipidomics Reveals Early Metabolic Changes in Subjects with Schizophrenia: Effects of Atypical Antipsychotics [PDF]

, 2013
There is a critical need for mapping early metabolic changes in schizophrenia to capture failures in regulation of biochemical pathways and networks.
Buckley, P, Kaddurah-Daouk, Rima, George G. Dougherty (436720), Peter Buckley (436718), Nasrallah Henry A., Joseph McEvoy, Baillie Rebecca A., Yao Jeffrey K., Nasrallah, HA, Zhu, H, Nasrallah, Henry A., Dougherty, GG, Zhu, Hongjie, Keshavan, Matcheri, Kaddurah-Daouk Rima, Peter Buckley, Keshavan, Matcheri S., Keshavan Matcheri S., Matcheri S Keshavan, Keshavan, MS, George G Dougherty, McEvoy, J, Hongjie Zhu (152174), Dougherty, George G., Henry A Nasrallah, Matcheri S. Keshavan (311472), Rima Kaddurah-Daouk (152187), Buckley Peter, Baillie, RA, McEvoy, Joseph, Hongjie Zhu, Rima Kaddurah-Daouk, McEvoy Joseph, Henry A. Nasrallah (436719), Yao, Jeffrey K., Joseph McEvoy (311475), Buckley, Peter, Kaddurah-Daouk, R, Rebecca A Baillie, Rebecca A. Baillie (152180), Dougherty George G., Jeffrey K Yao, Baillie, Rebecca A., Jeffrey K. Yao (311469), Yao, JK, Zhu Hongjie   +45 more
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Combined use of clozapine and cariprazine in treatment-resistant schizophrenia, is it a good choice?

European Psychiatry, 2021
Introduction Treatment-resistant schizophrenia (TRS) affects 30% of people with a diagnosis of schizophrenia, and is defined as nonresponse to at least two trials of antipsychotic medication of adequate dose and duration. Clozapine is the only evidence-
H. Becerra Darriba
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Thyroid function test abnormalities in treatment-resistant schizophrenia

Psychiatry and Clinical Psychopharmacology, 2021
Objective: The relationship between thyroid dysfunction and mood disorders is well recognized. Thyroid function abnormalities are bad prognostic factors in mood disorders, and augmentation with thyroid hormone has therapeutic efficacy in treatment ...
Ertac Sertac Orsel, Atila Erol, Hilal Kapudan, Semra Karayilan, Mustafa Ozten   +4 more
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A Case Report: Treatment Resistant Schizophrenia [PDF]

Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2004
Clinicians define resistance to treatment of schizophrenia, as a failure including functional and psyhcosocial dimensions despite adequate dosage, duration and treatment consistency.
Gamze Sönmez, Zeynep Alantar, Selime Çelik, Münevver Hacıoğlu, Taruk Kutlar, Oya Güçlü   +5 more
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A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia [PDF]

, 2009
We report a genome-wide assessment of single nucleotide polymorphisms (SNPs) and copy number variants (CNVs) in schizophrenia. We investigated SNPs using 871 patients and 863 controls, following up the top hits in four independent cohorts comprising 1 ...
Rujescu, D., Herbert Y Meltzer, Fraser, G., Gennarelli, Massimo, St. Clair, D, JAYATHILAKE K, Rossi Giuseppe, Feng, S, Gennarelli Massimo, Feng, Sheng, Fraser, G, KASPERAVICI, Ge, D., MELTZER HY, Strittmatter, WJ, Fisher, EMC, St Clair, David, RUPPERT A, ROSES AD, Rossi, Giuseppe, Ge Dongliang, Ge, DL, YOON W, NEED AC, David St Clair, RUJESCU D, Sheng Feng, Joseph P McEvoy, Meltzer, Herbert Y, Goldstein, DB, Yoon, Woohyun, St. Clair David, Goldstein, D., Lefkos T Middleton, Meltzer, H., Feng, S., Allen D Roses, Hartmann, Annette M., St Jean, PL, Middleton, Lefkos T., David B Goldstein, Yoon, W, Kasperaviciute, Dalia, Shianna, Kevin V, Moller, HJ, TE D, GOLDSTEIN DB, Kasperavičiūtė, D., Weale, Michael E., Meltzer, HY, FRASER G, Ruppert, A., Middleton, Lefkos T, St Jean, Pamela L, WEALE ME, Shianna, K., Fisher, Elizabeth M. C., Middleton Lefkos T., Heinzen Erin L., Heinzen, E., Crombie Caroline, Ina Giegling, McEvoy, Joseph P, Bonvicini, Cristian, Pamela L St Jean, St. Jean, Pamela L., Keefe, RSE, MÖLLER HJ, Heinzen, EL, Maia, J, Caroline Crombie, Hartmann, A., Need, Anna C, Muglia Pierandrea, Francks, Clyde, St Clair, D, FISHER EM, Dongliang Ge, Giegling Ina, Moeller, H-J, Pierandrea Muglia, Fisher Elizabeth M. C., Goldstein, David B, McEvoy, J., COLA PA, St. Jean Pamela L., Feng Sheng, Cola Philip A., Kasperaviciute, D, Kevin V Shianna, Need Anna C., Weale Michael E., Goldstein, David B., Jessica Maia, Giegling, I., Francks Clyde, Bonvicini, C., Muglia, P., Strittmatter, Warren J., Yoon, W., Ge, Dongliang, McEvoy, JP, Clyde Francks, ROSSI G, Gillian Fraser, Möller, H., Strittmatter, W., MCEVOY JP, St. Clair, D., Ruppert Andreas, Meltzer, Herbert Y., Shianna Kevin V., Fraser, Gillian, Cristian Bonvicini, Roses, Allen D., Gennarelli, M, Warren J Strittmatter, Moeller, Hans-Juergen, Meltzer Herbert Y., Fisher, E., CROMBIE C, Need, AC, Michael E Weale, Ruppert, A, Kasperavičiūtė Dalia, HEINZEN EL, Hartmann, AM, KEEFE RS, Giegling, I, Möller, Hans-Jürgen, Dan Rujescu, Bonvicini Cristian, Goldstein David B., ST CLAIR D, Need, A., Erin L Heinzen, Annette M Hartmann, Heinzen, Erin L, Francks, C, Elizabeth M C Fisher, Gennarelli, M., Muglia, Pierandrea, MIDDLETON LT, Richard S E Keefe, HARTMANN AM, Shianna, KV, Rujescu, Dan, McEvoy Joseph P., Crombie, C., Crombie, Caroline, Strittmatter, Warren J, Woohyun Yoon, Rujescu Dan, St. Jean, P., Ge, D, Karu Jayathilake, McEvoy, Joseph P., Cola, Philip A., Keefe, Richard S E, Jayathilake Karu, Anna C Need, Jayathilake, K., Giegling, Ina, FENG S, Yoon Woohyun, Middleton, LT, Heinzen, Erin L., Roses, Allen D, Cola, PA, Cola, Philip A, St. Clair, David, GE D, Andreas Ruppert, Strittmatter Warren J., Bonvicini, C, St. Jean, PL, Weale, M., Shianna, Kevin V., Cola, P., Rujescu, D, Philip A Cola, Giuseppe Rossi, Middleton, L., Möller Hans-Jürgen, Jayathilake, K, Weale, ME, Jayathilake, Karu, Roses, AD, FRANCKS C, MAIA J, Hartmann, Annette M, Keefe, R., Rossi, G., Roses Allen D., Muglia, P, ST JEAN PL, Roses, A., Fisher, Elizabeth M C, BONVICINI C, Ruppert, Andreas, Maia, Jessica, Massimo Gennarelli, Maia Jessica, GIEGLING I, Francks, C., Keefe Richard S. E., SHIANNA KV, Maia, J., MUGLIA P, Rossi, G, Dalia Kasperaviciūte, Fraser Gillian, Crombie, C, Weale, Michael E, Hartmann Annette M., Need, Anna C., Keefe, Richard S. E., Hans-Jürgen Möller, STRITTMATTER WJ   +218 more
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Before a Diagnosis of Schizophreniform Disorder is Made, All Causes of Secondary Psychosis Should Be Ruled Out

Acta Médica Portuguesa
N ...
João Gama Marques, Josef Finsterer
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