Results 41 to 50 of about 59,572 (271)

Iranian psychiatrists’ attitude towards clozapine use for patients with treatment-resistant schizophrenia: a nationwide survey

BMC Psychiatry, 2022
Background Clozapine has the greatest efficacy for treatment-resistant schizophrenia (TRS), even though its underutilization is not uncommon across different countries.
Leeba Rezaie, Azadeh Nazari, Roya Safari-Faramani, Shamarina Shohaimi, Habibolah Khazaie   +4 more
doaj   +1 more source

Clozapine prescription trends in Brazil in the last decade

Brazilian Journal of Psychiatry, 2022
Objective: Clozapine is a second-generation antipsychotic indicated for treatment-resistant schizophrenia. Studies in several countries have shown a low rate of clozapine use despite the fact that approximately 30% of schizophrenia cases are treatment ...
Raffael Massuda, Clarissa S. Gama, Paulo Belmonte-de-Abreu, Helio Elkis, David Freitas de Lucena, Rodrigo Bressan, Cristiano Noto, Ary Gadelha   +7 more
doaj   +1 more source

Cost of treatment in schizophrenia in six European countries [PDF]

, 2009
Background and aims: As part of an RCT in six European sites, the direct mental health care cost for 422 patients with schizophrenia was analysed according to how total and medication costs differed across sites and which variables were likely to predict
McCabe, R, Bullenkamp, J, Rössler, W, Torres-Gonzalez, F, Hansson, Lars, Lauber, Christoph, Martinez-Leal, Rafael, Salize, H, Durk Wiersma, Torres-Gonzales, F, Priebe, Stefan, McCabe, R., Martinez-Leal, R., Svensson, Bengt, McCabe, Rosemarie, Rosemarie McCabe, Hansson, Lars,, Hansson, L., van den Brink, R., Lars Hansson, Salize, HJ, Lauber, C., van den Brink, Rob, Martinez-Leal, R, Rafael Martinez-Leal, Hans Joachim Salize, Lauber, C, Priebe, S, Lund University., Salize, H.J., Wiersma, Durk, Torres-Gonzalez, Francisco, Reinhard, I, Iris Reinhard, Wiersma, D, Priebe, S., Christoph Lauber, Svensson, B., Wiersma, D., Svensson, Bengt,, Rob van den Brink, Roessler, Wulf, Reinhard, Iris, Jens Bullenkamp, Bullenkamp, J., Stefan Priebe, Francisco Torres-Gonzalez, Reinhard, I., Bullenkamp, Jens, Hansson, L, van den Brink, R, Wulf Rössler, Salize, Hans Joachim, Rossler, W., Svensson, B, Torres-Gonzalez, F., Bengt Svensson   +56 more
core   +1 more source

Polygenic Risk Score for Schizophrenia and Treatment-Resistant Schizophrenia [PDF]

Schizophrenia Bulletin, 2017
Treatment-resistant schizophrenia (TRS) affects around one-third of individuals with schizophrenia. Although a number of sociodemographic and clinical predictors of TRS have been identified, data on the genetic risk of TRS are sparse. We aimed to investigate the association between a polygenic risk score for schizophrenia and treatment resistance in ...
Wimberley, Theresa, Gasse, Christiane, Meier, Sandra Melanie, Agerbo, Esben, MacCabe, James H, Horsdal, Henriette Thisted   +5 more
openaire   +5 more sources

Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collections. [PDF]

, 2010
Despite significant research efforts aimed at understanding the neurobiological underpinnings of psychiatric disorders, the diagnosis and the evaluation of treatment of these disorders are still based solely on relatively subjective assessment of ...
Brittain, Claire, Holsboer, Florian, Alexander, R. C., Inga Prokopenko, Robert C Alexander, Rujescu, D., Enrico Domenici, Bullmore, E., Giegling, Ina, Tozzi, F., Claire Brittain, Prokopenko, I, Turck, C., Ina Giegling, Merlo-Pich, E, Middleton, Lefkos, Wille, DR, Tozzi, Federica, Domenici, Enrico, Merlo-Pich, Emilio, Willé, David R., Miller, Sam, Astrid McKeown, Domenici, E, Edward T Bullmore, Middleton, L, Bullmore, ET, Alexander, Robert C., Tozzi, F, Robert C. Alexander, Holsboer, F, Emilio Merlo-Pich, Merlo-Pich, E., Rujescu, D, Sam Miller, McKeown, A, Middleton, L., Christoph W Turck, Federica Tozzi, Enrico Domenici, Prokopenko, I., Wille, D., David R Willé, Pierandrea Muglia, Giegling, I, McKeown, A., Turck, CW, Holsboer, F., Dan Rujescu, Bullmore, Edward T., Wille, D. R., Brittain, C, Christoph W. Turck, McKeown, Astrid, Muglia, P, Alexander, RC, Prokopenko, Inga, Miller, S., Giegling, I., Alexander, R., Muglia, P., Bullmore, E. T., David R. Willé, Edward T. Bullmore, Muglia, Pierandrea, Turck, C. W., Florian Holsboer, Brittain, C., Miller, S, Lefkos Middleton, Domenici, E., Turck, Christoph W., Rujescu, Dan   +72 more
core   +1 more source

Psychological treatments in schizophrenia: I. Meta-analysis of family intervention and cognitive behaviour therapy

, 2002
Background. While there is a growing body of evidence on the efficacy of psychological interventions for schizophrenia, this meta-analysis improves upon previous systematic and meta-analytical reviews by including a wider range of randomized controlled ...
Pilling, S., Geddes, J., Morgan, C, Geddes, J, Kuipers, E, Bebbington, P., Garety, P, Morgan, C., Orbach, G., Garety, P., Bebbington, P, Garety, P; id_orcid, Pilling, S, Orbach, G, Kuipers, E; id_orcid, Kuipers, E.   +15 more
core   +1 more source

Bias‐Field Free Single‐Frequency CW‐ODMR of Nitrogen‐Vacancy Centers in Diamond for the Detection of Transient Electrical Signals

Advanced Materials Interfaces, EarlyView.
Simplified quantum sensing technique for the detection of short electrical signals occurring in neuronal signaling or bioinspired technologies. We demonstrate a single frequency continuous‐wave optically detected magnetic resonance (CW‐ODMR) approach to sense signals that can be as short as 0.2 ms.
João Paulo Silva, Orlando D. Cunha, Pedro Magalhães, Filipe Camarneiro, Jana B. Nieder   +4 more
wiley   +1 more source

Dimensions of the AI Divide: Digital Inequality and Psychological Consequences

AI &Innovation, EarlyView.
ABSTRACT Artificial intelligence (AI) has become a foundational component of contemporary social, economic, and political life. Yet, the ways in which AI reshapes patterns of exclusion beyond questions of access and technical capability remain insufficiently theorized.
Christos Papaioannou
wiley   +1 more source

White Matter in Schizophrenia Treatment Resistance [PDF]

American Journal of Psychiatry, 2019
Failure of antipsychotic medications to resolve symptoms in patients with schizophrenia creates a clinical challenge that is known as treatment resistance. The causes of treatment resistance are unknown, but it is associated with earlier age at onset and more severe cognitive deficits.
Peter, Kochunov, Junchao, Huang, Song, Chen, Yanli, Li, Shuping, Tan, Fengmei, Fan, Wei, Feng, Yunhui, Wang, Laura M, Rowland, Anya, Savransky, Xiaoming, Du, Joshua, Chiappelli, Shuo, Chen, Neda, Jahanshad, Paul M, Thompson, Meghann C, Ryan, Bhim, Adhikari, Hemalatha, Sampath, Yimin, Cui, Zhiren, Wang, Fude, Yang, Yunlong, Tan, L Elliot, Hong   +22 more
openaire   +2 more sources

Clinical, Behavioral and Neuroradiological Phenotype in an Italian Cohort of Patients With Xia Gibbs Syndrome: A Multicenter Cross‐Sectional Study and Systematic Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous variants in the AHDC1 gene are associated with Xia Gibbs Syndrome (XGS), a genetic disorder with a highly variable phenotype. Cognitive impairment, motor delay, language delay, neonatal hypotonia, and sleep apnea are considered “cardinal” signs of the disease.
Giulia Cinelli, Stefania Della Vecchia, Patrizia Bergonzini, Elisa Caramaschi, Elisabetta Spezia, Claudia Parenti, Simona Filomena Madeo, Laura Lucaccioni, Cavalleri Francesca, Marisa Pugliese, Federico Raviglione, Clara Colonna, Olga Calabrese, Ilaria Stanghellini, Maria Carmen Marongiu, Enrico Biagioni, Anna Rita Ferrari, Roberta Battini, Lorenzo Iughetti   +18 more
wiley   +1 more source