Results 21 to 30 of about 59,572 (271)

Dissociative Model in Patients With Resistant Schizophrenia

open access: yesFrontiers in Psychiatry, 2022
BackgroundSchizophrenia is a severe mental illness in which, despite the growing number of antipsychotics from 30 to 50% of patients remain resistant to treatment. Many resistance factors have been identified.
Georgi Panov
doaj   +1 more source

Selective Serotonin Reuptake Inhibitors and Clozapine: Clinically Relevant Interactions and Considerations

open access: yesNeurology International, 2021
The monoamine hypothesis of depression attributes the symptoms of major depressive disorders to imbalances of serotonin, noradrenaline, and dopamine in the limbic areas of the brain.
Amber N. Edinoff   +7 more
doaj   +1 more source

Barriers to using clozapine in treatment-resistant schizophrenia: systematic review [PDF]

open access: yes, 2019
Aims and methodTo systematically review the literature on barriers to the use of clozapine and identify any interventions for optimizing clozapine use in treatment-resistant schizophrenia. Journal databases were searched from 1972 to March 2018.
Farooq
core   +1 more source

Prevalence and predictors of treatment-resistant schizophrenia in a tertiary hospital in Northeast Brazil

open access: yesTrends in Psychiatry and Psychotherapy, 2021
Objective To investigate epidemiological factors related to treatment-resistant schizophrenia (TRS) in Northeast Brazil, a region where data about mental health are still scarce.
Douglas de Sousa Soares   +4 more
doaj   +1 more source

Neuroimaging glutamatergic mechanisms differentiating antipsychotic treatment-response

open access: yesScientific Reports, 2023
Glutamatergic dysfunction is associated with failure to respond to antipsychotic medication in individuals with schizophrenia. Our objective was to combine neurochemical and functional brain imaging methods to investigate glutamatergic dysfunction and ...
Elias D. Mouchlianitis   +5 more
doaj   +1 more source

Treatment-Resistant Schizophrenia

open access: yesFocus, 2020
Although, gratifyingly, research on the treatment of schizophrenia has increasingly focused on first-episode and prodromal patient populations, it is still recognized that many patients with more chronic illnesses exhibit a suboptimal response to treatments.
openaire   +3 more sources

Metacognitive Therapy in Treatment-Resistant Psychosis:A Multiple-Baseline Study [PDF]

open access: yes, 2013
Background: More effective psychological treatments for psychosis are required. Case series data and pilot trials suggest metacognitive therapy (MCT) is a promising treatment for anxiety and depression.
Wardle, Melissa   +8 more
core   +1 more source

Clozapine in Treatment-Resistant Schizophrenia and Its Augmentation with Electroconvulsive Therapy in Ultra-Treatment-Resistant Schizophrenia

open access: yesBiomedicines, 2023
Clozapine is considered the gold standard for patients with treatment-resistant schizophrenia (TRS) who have previously tried other antipsychotics at adequate doses (two or more, with at least one being atypical).
Vjekoslav Peitl   +5 more
doaj   +1 more source

No association of rs1065852 and rs3892097 polymorphisms gene CYP2D6 with treatment resistant schizophrenia

open access: yesОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2019
According to modern data, about a third of patients suffering from schizophrenia are considered treatment resistant. The metabolism of about 20% of medicines and mainly psychotropic drugs is caused by the isoenzyme CYP2D6.
D. N. Sosin   +4 more
doaj   +1 more source

Generation of ultra-treatment-resistant schizophrenia patient-derived induced pluripotent stem cell line UJSi002-A

open access: yesStem Cell Research, 2022
Schizophrenia is a chronic, serious and disabling mental disorder. Most patients can effectively control their condition through drug treatment, but there are still some patients who are difficult to gain benefits from drug treatment.
Jing Sun   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy