Results 121 to 130 of about 8,731 (307)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Alteração da superfície de sistemas de implantes dentários em fluoreto de sódio e peróxido de hidrogênio [PDF]

open access: yes, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Odontologia, Florianópolis, 2014Atualmente o titânio e suas ligas são os materiais mais utilizados na área da Implantodontia por ...
Penãrrieta Juanito, Gabriella Mercedes
core  

Schützen nützt – Netzwerk Europäische Wildrebe

open access: yesJulius-Kühn-Archiv, 2020
Nick, Peter
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Produção e avaliação do uso de pozolana com baixo teor de carbono obtida da cinza de casca de arroz residual para concreto de alto desempenho [PDF]

open access: yes, 2006
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Civil.Os benefícios da utilização da cinza de casca de arroz como adição pozolânica em argamassas e concretos têm sido amplamente ...
Santos, Silvia
core  

The Combinatorics of Effective Resistances and Resistive Inverses

open access: yesInformation and Computation, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Gitlin, Andrew, and Frank Margouis, The Political Aspects of Reform: Teacher Resistence as Good Sense, American Journal of Education, 103 (August, 1995), 377-405.*

open access: yes, 1995
Reviews literature on change and school culture; reports a study of teacher resistence to change in one elementary ...
Gitlin, Andrew, Margouis, Frank
core  

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