Results 141 to 150 of about 2,873 (264)

Telerehabilitation in cystic fibrosis: a randomized clinical trial protocol for increasing exercise loads and difficulty levels (TeleCist). [PDF]

Trials
Paula ÍR, Ronchi CF, Oliveira Azevedo VMG.   +2 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

How has structuring your ideas into protocols contributed to your research progress and facilitated collaboration with others in the field? [PDF]

STAR Protoc
Zhang X, Shokri L.
europepmc   +1 more source

What's new in intensive care: disease tolerance. [PDF]

Intensive Care Med, 2023
Powell RE, Soares MP, Weis S.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

The impact of sulfadoxine-pyrimethamine resistance on the effectiveness of intermittent preventive treatment for the prevention of malaria in pregnancy in Africa: an updated systematic review and meta-analysis. [PDF]

Lancet Infect Dis
van Eijk AM, Stepniewska K, Khairallah C, Rodriguez E, Ahn J, Gutman JR, Ter Kuile FO, IPTp-SP Effectiveness Study group.   +7 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Regards

Cahiers de Civilisation Espagnole Contemporaine, 2007
Marie-Claude Chaput, Manuelle Peloille
doaj   +1 more source

A Set of Multiresistant Isolates of <i>Mycoplasma bovis</i> Subtype ST-1 with a Variable Susceptibility to Quinolones Are Also Circulating in Spain. [PDF]

Pathogens
Corrales JC, Sánchez A, Hernández X, Amores-Iniesta J, Esnal A, de la Fe C.   +5 more
europepmc   +1 more source

Editorial: Challenges in the contemporary assessment of coronary physiology. [PDF]

Front Cardiovasc Med, 2023
Aleksandric S, Tesic M, Orlic D.
europepmc   +1 more source