Results 81 to 90 of about 608,135 (288)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

De la femme ordinaire à la femme résistante : aspects de dramatisation de l’Algérienne chez Assia Djebar et Fatima Gallaire

open access: yesAcademic Journal of Modern Philology
Our study aims to approach the evolution of female identity and consciousness in two contemporary French-speaking Algerian women writers. In this context, our work will have the plays Rouge l'Aube [The Red Dawn] (1958–1959) by Assia Djebar and Princesses
Christina Oikonomopoulou
doaj   +1 more source

Some causes of differences in the NH3 concentration measured with the semiconductor sensors by one manufacturer

open access: yesResearch in Agricultural Engineering, 2016
The paper deals with continuous monitoring of NH3 desorption from material used as bedding in animal breeding establishments, using five semiconductor sensors SP-53 (FIS Inc.).
P. Zabloudilová, J. Pecen, M. Češpiva
doaj   +1 more source

ANTIBIOTIC RESISTANCE

open access: yesCritical Care Clinics, 1998
Antibiotic resistance is an increasing problem in many parts of the world. Antibiotic resistance has been associated with the use of some antibiotics but not with others. Due to the overuse of antibiotics with a high resistance potential, there has been an increase of resistance with certain bacteria, e.g., Staphylococcus aureus, Pseudomonas aeruginosa
openaire   +3 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Functional System of Lysozyme and Anti-Lysozyme in Plague Agent and Flea Organism Interralations

open access: yesПроблемы особо опасных инфекций, 2009
Lysozyme is shown to be one of the factors of flea`s natural non-specific resistence. Lysozyme is detected in various species of rodents fleas. Besides, some plague agent strains are shown to possess anti-lysozyme activity.
N.V. Sakhno
doaj   +1 more source

Non invasive evaluation of liver fibrosis in paediatric patients with nonalcoholic steatohepatitis.

open access: yesWorld Journal of Gastroenterology, 2006
AIM To identify the independent predictors of hepatic fibrosis in 69 children with nonalcoholic steatohepatitis (NASH) due to nonalcoholic fatty liver disease (NAFLD).
A. Iacobellis   +6 more
semanticscholar   +1 more source

Resistant Hypertension or Resistant Prescribing? [PDF]

open access: yesHypertension, 2011
See related article, pp 1008–1013 The term “resistant hypertension” (RH) evokes a myriad of clinical descriptions, nearly all of which implicitly ascribe origins of the problem to characteristics inherent within the patient or maleficent qualities of the disease itself.
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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