Results 81 to 90 of about 5,034,272 (293)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Objective: To evaluate the diagnostic accuracy of resistive index in Doppler Imaging in diagnosing benign and malignant adnexal masses, taking Histopathology as Gold standard. Study Design: Prospective observational study.
Nadia Irshad +2 more
doaj
Background: Chronic kidney disease encompasses a spectrum of different pathophysiological processes associated with abnormal renal function and a progressive decline in glomerular filtration rate. Duplex ultrasonography is widely available and important
Karun Devkota +3 more
doaj +1 more source
The early identification of infertile males improves reproduction efficiency at a production level and is essential to secure high production rates. Before entering a breeding program, males must pass an initial breeding soundness examination (BSE) which
Ana Velasco, Salvador Ruiz
doaj +1 more source
An increase of glomerular filtration rate after protein load represents renal functional reserve (RFR) and is due to afferent arteriolar vasodilation. Lack of RFR may be a risk factor for acute kidney injury (AKI), but is cumbersome to measure. We sought
S. Samoni +9 more
semanticscholar +1 more source
Thermally-Reconfigurable Quantum Photonic Circuits at Telecom Wavelength by Femtosecond Laser Micromachining [PDF]
The importance of integrated quantum photonics in the telecom band resides on the possibility of interfacing with the optical network infrastructure developed for classical communications.
Crespi, Andrea +10 more
core +3 more sources
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Topological constraints on magnetic field relaxation
Magnetic field relaxation is determined by both the field's geometry and its topology. For relaxation processes, however, it turns out that its topology is a much more stringent constraint. As quantifier for the topology we use magnetic helicity and test
Brandenburg, Axel, Candelaresi, Simon
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Diagnosis of Polycystic Ovarian Syndrome on Doppler Based Resistive Index and Pulsatility Index
Background: To determine Doppler based mean Pulsatility index and mean Resistive index in patient diagnosed with polycystic ovary syndrome. Methods: In this cross sectional study one hundred and twenty patients with clinical diagnosis of polycystic Ovary
Asma Bano
doaj

