Results 181 to 190 of about 11,619 (200)

Size effects of microplastics on antibiotic resistome and core microbiome in an urban river.

Science of the Total Environment
Microplastics (MPs) in aquatic environments provide a new ecological niche that facilitates the attachment of antibiotic-resistance genes (ARGs) and pathogens.
Wenfang Lin, Shaoheng Cao, Qihui Wu, Fei Xu, Ruilong Li, Li Cui   +5 more
semanticscholar   +1 more source

Distinct Assembly Patterns of Soil Antibiotic Resistome Revealed by Land-Use Changes over 30 Years.

Environmental Science and Technology
Compared with the ever-growing information about the anthropogenic discharge of nutrients, metals, and antibiotics on the disturbance of antibiotic resistance genes (ARGs), less is known about how the potential natural stressors drive the evolutionary ...
Yu-Hao Fu, Fang Hu, Fang Wang, Min Xu, Zhongjun Jia, W. Amelung, Zhi Mei, Xiaozeng Han, M. Virta, Xin Jiang, J. Tiedje   +10 more
semanticscholar   +1 more source

Global diversity, coexistence and consequences of resistome in inland waters.

Water Research
Human activities have long impacted the health of Earth's rivers and lakes. These inland waters, crucial for our survival and productivity, have suffered from contamination which allows the formation and spread of antibiotic-resistant genes (ARGs) and ...
Bin-Hao Wang, Bin Ma, Yi-Nan Zhang, E. Stirling, Qing-Yun Yan, Zhi-Li He, Zhi-Quan Liu, Xia Yuan, Hang-Jun Zhang   +8 more
semanticscholar   +1 more source

Migration of fungicides, antibiotics and resistome in the soil-lettuce system.

Journal of Hazardous Materials
The emergence and spread of antibiotic resistance genes (ARGs) have become a serious issue in global agricultural production. However, understanding how these ARGs spread across different spatial scales, especially when exposed to both pesticides and ...
Chen-Yu Huang, Minrong Cui, Tongxin Li, Cong-Lai Zheng, Mengting Qiu, Shang-Hai Mei, Baotong Li, Lu-Qing Zhang, Yun-Long Yu, Hua Fang   +9 more
semanticscholar   +1 more source

The mystery of rich human gut antibiotic resistome in the Yellow River with hyper-concentrated sediment-laden flow.

Water Research
Human gut antibiotic resistome widely occur in anoxic environments characterized by high density of bacterial cells and frequent transmission of antibiotic resistance genes (ARGs).
Yuan Gao, Qian Chen, Shu-Feng Liu, Jia-Wen Wang, A. Borthwick, Jinren Ni   +5 more
semanticscholar   +1 more source

The Antibiotic Resistome: Challenge And Opportunity For Therapeutic Intervention

Future Medicinal Chemistry, 2012
Despite the relevance of infectious disease as main causes of human morbidity and mortality, the development of new antibacterials is not among the highest priorities for pharmaceutical companies. Regulatory and economic issues, together with the lack of novel targets, might justify the reduced rate of discovery of new antimicrobials.
openaire   +2 more sources

Metagenomic insights into resistome coalescence in an urban sewage treatment plant-river system

Water Research, 2022
Yanguo Teng, Chang Liu
exaly  

Antibiotic resistome associated with inhalable bioaerosols from wastewater to atmosphere: Mobility, bacterial hosts, source contributions and resistome risk

Water Research, 2023
Tang Yang, Shujuan Huang, How Yong Ng
exaly  

The resistance within: Antibiotic disruption of the gut microbiome and resistome dynamics in infancy

Cell Host and Microbe, 2022
Sanjam S Sawhney, Robert Thaenert, Gautam Dantas   +2 more
exaly  

Novel antibiotic discovery and the antibiotic resistome

Expert Opinion on Drug Discovery
The success of antibiotics in the therapy of infectious diseases is overshadowed by almost inevitable emergence and dissemination of resistances toward these agents, which results in higher morbidity and mortality rates and increased costs. New strategies are now needed to both limit the risk of resistance and to discover new drugs that are efficacious.
openaire   +2 more sources