Results 191 to 200 of about 11,688 (211)

The soil antibiotic resistome

Moscow University Soil Science Bulletin, 2013
Antibiotic resistance of pathogenic microorganisms is considered to be an important and urgent public health problem. Rapid and large-scale development of antibiotic resistance at a global level actually means a return to the pre-antibiotic age. The soil resistome conception includes all genetic components of antibiotic resistance that are present in a
P. A. Kozhevin, K. A. Vinogradova, V. G. Bulgakova   +2 more
openaire   +1 more source

Metatranscriptome and Resistome of the Endodontic Microbiome

Journal of Endodontics
INTRODUCTION In this study, we used metatranscriptomics for the first time to investigate microbial composition, functional signatures, and antimicrobial resistance gene expression in endodontic infections. METHODS Root canal samples were collected from ten teeth, including five primary and five persistent/secondary endodontic infections.
Pinheiro, Ericka T, Karygianni, Lamprini, Candeiro, George T M, Vilela, Bruna G, Dantas, Larissa O, Pereira, Ana C C, Gomes, Brenda P F A, Attin, Thomas, Thurnheer, Thomas, Russo, Giancarlo   +9 more
openaire   +2 more sources

Lessons from the Environmental Antibiotic Resistome

Annual Review of Microbiology, 2017
Antibiotic resistance is a global public health issue of growing proportions. All antibiotics are susceptible to resistance. The evidence is now clear that the environment is the single largest source and reservoir of resistance. Soil, aquatic, atmospheric, animal-associated, and built ecosystems are home to microbes that harbor antibiotic resistance ...
Matthew D, Surette, Gerard D, Wright
openaire   +2 more sources

Analysis of the MCMV resistome by ENU mutagenesis

Mammalian Genome, 2006
The mouse cytomegalovirus (MCMV) resistome is the set of host genes with nonredundant functions in resistance to MCMV infection. By screening 3,500 G(3) germline mutant mice ( approximately 1,750 gamete equivalents), we have identified eight transmissible mutations that create MCMV susceptibility in C57BL/6 mice.
Karine, Crozat, Philippe, Georgel, Sophie, Rutschmann, Navjiwan, Mann, Xin, Du, Kasper, Hoebe, Bruce, Beutler   +6 more
openaire   +2 more sources

The resistance within: Antibiotic disruption of the gut microbiome and resistome dynamics in infancy

Cell Host and Microbe, 2022
Robert Thanert, Sanjam S Sawhney, Drew J Schwartz   +2 more
exaly  

Novel antibiotic discovery and the antibiotic resistome

Expert Opinion on Drug Discovery
The success of antibiotics in the therapy of infectious diseases is overshadowed by almost inevitable emergence and dissemination of resistances toward these agents, which results in higher morbidity and mortality rates and increased costs. New strategies are now needed to both limit the risk of resistance and to discover new drugs that are efficacious.
openaire   +2 more sources

Predicting Pseudomonas aeruginosa susceptibility phenotypes from whole genome sequence resistome analysis

Clinical Microbiology and Infection, 2021
Sara Cortés-Lara, Ester Del Barrio-Tofiño, Carla López-Causapé   +2 more
exaly  

Antibiotic resistome of Salmonella typhi: molecular determinants for the emergence of drug resistance

Frontiers of Medicine, 2021
Awanish Kumar, Anil Kumar, Kumar Awanish   +2 more
exaly  

Metagenomics Reveals a Core Macrolide Resistome Related to Microbiota in Chronic Respiratory Disease

American Journal of Respiratory and Critical Care Medicine, 2020
Micheal Mac Aogáin, Kenny J X Lau, Zhao Cai   +2 more
exaly  

Environmental resistome risks of wastewaters and aquatic environments deciphered by shotgun metagenomic assembly

Ecotoxicology and Environmental Safety, 2020
Mutshiene Deogratias Ekwanzala, Maggy Ndombo Benteke Momba   +1 more
exaly