Results 211 to 220 of about 19,820 (248)

The intrinsic resistome of Klebsiella pneumoniae

International Journal of Antimicrobial Agents, 2019
Molecular epidemiology studies aiming at understanding the acquisition of antimicrobial resistance by clinical isolates of Klebsiella pneumoniae are regularly published; however, information on the genes that contribute to its characteristic phenotype of resistance to antibiotics (intrinsic resistome) is scarce. To fill this gap, a K.
Bernardini, Alejandra, Cuesta, Trinidad, Tomás, Anna, Bengoechea, José A., Martínez, José L., Sánchez, María B.   +5 more
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The antibiotic resistome

Expert Opinion on Drug Discovery, 2010
Antibiotics are essential for the treatment of bacterial infections and are among our most important drugs. Resistance has emerged to all classes of antibiotics in clinical use. Antibiotic resistance has, proven inevitable and very often it emerges rapidly after the introduction of a drug into the clinic.
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Antimicrobial resistomes in food chain microbiomes

Critical Reviews in Food Science and Nutrition, 2023
The safety and integrity of the global food system is in a constant state of flux with persistent chemical and microbial risks. While chemical risks are being managed systematically, microbial risks pose extra challenges. Antimicrobial resistant microorganism and persistence of related antibiotic resistance genes (ARGs) in the food chain adds an extra ...
Mengqi, Yuan, Zhenhua, Huang, Pradeep K, Malakar, Yingjie, Pan, Yong, Zhao, Zhaohuan, Zhang   +5 more
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Deciphering basic and key traits of antibiotic resistome in influent and effluent of hospital wastewater treatment systems.

Water Research, 2023
Hospital wastewater treatment system (HWTS) is an important source and environmental reservoir of clinically relevant antibiotic resistance genes (ARGs).
Lin Zhu, Ling Yuan, Xin-Yi Shuai, Ze-Jun Lin, Yujie Sun, Zhen-Chao Zhou, Lingxuan Meng, Feng Ju, Hong Chen   +8 more
semanticscholar   +1 more source

Forces shaping the antibiotic resistome

BioEssays, 2014
Antibiotic resistance has become a problem of global scale. Resistance arises through mutation or through the acquisition of resistance gene(s) from other bacteria in a process called horizontal gene transfer (HGT). While HGT is recognized as an important factor in the dissemination of resistance genes in clinical pathogens, its role in the environment
Julie A, Perry, Gerard D, Wright
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Hypervariation and phase variation in the bacteriophage ‘resistome’

Current Opinion in Microbiology, 2007
Most bacteria encode proteins for defence against infection by bacteriophages. The mechanisms that bring about phage defence are extremely diverse, suggesting frequent independent evolution of novel processes. Phage defence determinants are often plasmid or phage-encoded and many that are chromosomal show evidence of lateral transfer. Recent studies on
Hoskisson, P., Smith, M.C.M.
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Biofilms on pipelines shape the microbiome and antibiotic resistome in drinking water.

Water Research
Biofilms in the drinking water distribution system (DWDS) provide shelter for pathogens and antibiotic resistance genes (ARGs). However, how biofilms alter the microbiome and antibiotic resistome in tap water, as well as the precise quantitative ...
Wenfang Lin, Keqian Zhao, Qihui Wu, Fei Xu, Lian-Qi Cui, Hui-Rong Lin, Cheng-Song Ye, Xin Yu   +7 more
semanticscholar   +1 more source

Metatranscriptome and Resistome of the Endodontic Microbiome

Journal of Endodontics
INTRODUCTION In this study, we used metatranscriptomics for the first time to investigate microbial composition, functional signatures, and antimicrobial resistance gene expression in endodontic infections. METHODS Root canal samples were collected from ten teeth, including five primary and five persistent/secondary endodontic infections.
Pinheiro, Ericka T, Karygianni, Lamprini, Candeiro, George T M, Vilela, Bruna G, Dantas, Larissa O, Pereira, Ana C C, Gomes, Brenda P F A, Attin, Thomas, Thurnheer, Thomas, Russo, Giancarlo   +9 more
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The soil antibiotic resistome

Moscow University Soil Science Bulletin, 2013
Antibiotic resistance of pathogenic microorganisms is considered to be an important and urgent public health problem. Rapid and large-scale development of antibiotic resistance at a global level actually means a return to the pre-antibiotic age. The soil resistome conception includes all genetic components of antibiotic resistance that are present in a
P. A. Kozhevin, K. A. Vinogradova, V. G. Bulgakova   +2 more
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Microcosm experiments deciphered resistome coalescence, risks and source-sink relationship of antibiotic resistance in the soil irrigated with reclaimed water.

Journal of Hazardous Materials
Reclaimed water is widely used in agriculture irrigation to alleviate water scarcity, whereas the dissemination of antibiotic resistance genes (ARGs) in the soil it introduces has attracted widespread attention. Currently, few studies have systematically
Yiyi Liu, Shan Xin, Chang Liu, Hai-Yang Chen   +3 more
semanticscholar   +1 more source