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Insight into environmental adaptability of antibiotic resistome from surface water to deep sediments in anthropogenic lakes by metagenomics.

Water Research
The escalating antibiotic resistance threatens the long-term global health. Lake sediment is a vital hotpot in transmitting antibiotic resistance genes (ARGs); however, their vertical distribution pattern and driving mechanisms in sediment cores remain ...
Cong Wang   +4 more
semanticscholar   +1 more source

Analysis of the MCMV resistome by ENU mutagenesis

Mammalian Genome, 2006
The mouse cytomegalovirus (MCMV) resistome is the set of host genes with nonredundant functions in resistance to MCMV infection. By screening 3,500 G(3) germline mutant mice ( approximately 1,750 gamete equivalents), we have identified eight transmissible mutations that create MCMV susceptibility in C57BL/6 mice.
Karine, Crozat   +6 more
openaire   +2 more sources

Antibiotic resistome in landfill leachate and impact on groundwater.

Science of the Total Environment
Landfill leachate is a hotspot in antibiotic resistance development. However, little is known about antibiotic resistome and host pathogens in leachate and their effects on surrounding groundwater.
Wei-Li Jia   +8 more
semanticscholar   +1 more source

Lessons from the Environmental Antibiotic Resistome

Annual Review of Microbiology, 2017
Antibiotic resistance is a global public health issue of growing proportions. All antibiotics are susceptible to resistance. The evidence is now clear that the environment is the single largest source and reservoir of resistance. Soil, aquatic, atmospheric, animal-associated, and built ecosystems are home to microbes that harbor antibiotic resistance ...
Matthew D, Surette, Gerard D, Wright
openaire   +2 more sources

Synergistic Control of Trimethoprim and the Antimicrobial Resistome in Electrogenic Microbial Communities.

Environmental Science and Technology
Synergistic control of the risks posed by emerging antimicrobials and antibiotic resistance genes (ARGs) is crucial for ensuring ecological safety. Although electrogenic respiration can enhance the biodegradation of several antimicrobials and reduce ARGs
Yaoli Wei   +7 more
semanticscholar   +1 more source

Size effects of microplastics on antibiotic resistome and core microbiome in an urban river.

Science of the Total Environment
Microplastics (MPs) in aquatic environments provide a new ecological niche that facilitates the attachment of antibiotic-resistance genes (ARGs) and pathogens.
Wenfang Lin   +5 more
semanticscholar   +1 more source

Distinct Assembly Patterns of Soil Antibiotic Resistome Revealed by Land-Use Changes over 30 Years.

Environmental Science and Technology
Compared with the ever-growing information about the anthropogenic discharge of nutrients, metals, and antibiotics on the disturbance of antibiotic resistance genes (ARGs), less is known about how the potential natural stressors drive the evolutionary ...
Yu-Hao Fu   +10 more
semanticscholar   +1 more source

Airborne antibiotic resistome from sludge dewatering systems: Mobility, pathogen accessibility, cross-media migration propensity, impacting factors, and risks.

Water Research
Bioaerosol contamination was considered as a potential health threat in sludge dewatering systems (SDSs), while emission and risk of airborne antibiotic resistome remain largely unclear.
Tang Yang   +5 more
semanticscholar   +1 more source

Global diversity, coexistence and consequences of resistome in inland waters.

Water Research
Human activities have long impacted the health of Earth's rivers and lakes. These inland waters, crucial for our survival and productivity, have suffered from contamination which allows the formation and spread of antibiotic-resistant genes (ARGs) and ...
Bin-Hao Wang   +8 more
semanticscholar   +1 more source

The mystery of rich human gut antibiotic resistome in the Yellow River with hyper-concentrated sediment-laden flow.

Water Research
Human gut antibiotic resistome widely occur in anoxic environments characterized by high density of bacterial cells and frequent transmission of antibiotic resistance genes (ARGs).
Yuan Gao   +5 more
semanticscholar   +1 more source

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