Results 51 to 60 of about 18,536 (211)

The Antibiotic Resistance ‘Mobilome’: searching for the link between environment and clinic.

Frontiers in Microbiology, 2013
Antibiotic resistance is an ancient problem, owing to the co-evolution of antibiotic-producing and target organisms in the soil and other environments over millennia.
Julie ePerry, Julie ePerry, Gerard eWright, Gerard eWright   +3 more
doaj   +1 more source

Perinatal risk factors for fecal antibiotic resistance gene patterns in pregnant women and their infants.

PLoS ONE, 2020
Perinatal factors can shape fecal microbiome patterns among pregnant women and their infants. However, there is scarce information about the effect of maternal demographics and perinatal exposures on antibiotic resistance genes (ARG) and mobile genetic ...
Andrea Sosa-Moreno, Sarah S Comstock, Kameron Y Sugino, Teng F Ma, Nigel Paneth, Yelena Davis, Rosemary Olivero, Rebecca Schein, Joel Maurer, Lixin Zhang   +9 more
doaj   +1 more source

The Environmental Exposures and Inner- and Intercity Traffic Flows of the Metro System May Contribute to the Skin Microbiome and Resistome [PDF]

, 2018
The skin functions as the primary interface between the human body and the external environment. To understand how the microbiome varies within urban mass transit and influences the skin microbiota, we profiled the human palm microbiome after contact ...
Archna, Anand, Baker, David Michael, Denizen, Seth, Dingle, Caroline, Heshiki, Yoshitaro, Imamovic, Lejla, Kang, Kang, Kobler, Marie Danielle, Kumari, Sarika, Li, Jun, Ni, Yueqiong, Panagiotou, Gianni, Sarkar, Chinmoy, Sommer, Morten Otto Alexander, Webster, Christopher John, Wong, Cheong Wai Martin, Wong, Jane Ching Yan, Zheng, Tingting   +17 more
core   +2 more sources

A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats

Advanced Science, EarlyView.
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang, Heqi Wu, Mengqi Qu, Chunge Zhang, Ziqian Xu, Yuhang Pei, Chaochao Zhao, Jiangtao Wang, Sufang Ma, Na Lyu, Xuebin Xu, Yuhai Bi, Baoli Zhu, George F. Gao   +13 more
wiley   +1 more source

Impacts of florfenicol on the microbiota landscape and resistome as revealed by metagenomic analysis. [PDF]

, 2019
BACKGROUND:Drug-resistant fish pathogens can cause significant economic loss to fish farmers. Since 2012, florfenicol has become an approved drug for treating both septicemia and columnaris diseases in freshwater fish.
Liao, Chao, Terhune, Jeffery, Wang, Luxin, Zeng, Qifan   +3 more
core  

Antibiotics as selectors and accelerators 1 of diversity in the mechanisms of resistance: from the resistome to genetic plasticity in the β-lactamases world [PDF]

, 2013
Antibiotics and antibiotic resistance determinants, natural molecules closely related to bacterial physiology and consistent with an ancient origin, are not only present in antibiotic-producing bacteria.
Cantón, Rafael, Galán, Juan Carlos, González Candelas, Fernando, Rolain, Jean-Marc   +3 more
core   +3 more sources

Pharmacokinetics of Long‐Acting Ampicillin and Its Impact on the Gut Microbiome and Resistome in Rhesus Macaques (Macaca mulatta)

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Injectable antimicrobials with documented prolonged dosing intervals (> 48 h) for use in rhesus macaques are sparse. The objective of our study was to assess the pharmacokinetics, urine excretion, and effects on gut microbiome and resistome of intramuscular administered long‐acting formulation of ampicillin (Albipen LA) in macaques.
Annemiek Maaskant, Ingeborg M. van Geijlswijk, Mathias Devreese, Marc Cherlet, Leo F. van Geest, Jaap A. Wagenaar, Jan A. M. Langermans, Aldert L. Zomer, Jaco Bakker, Ronette Gehring   +9 more
wiley   +1 more source

The European livestock resistome

mSystems
ABSTRACT Metagenomic sequencing has proven to be a powerful tool in the monitoring of antimicrobial resistance (AMR). Here, we provide a comparative analysis of the resistome from pigs, poultry, veal calves, turkey, and rainbow trout, for a total of 538 herds across nine European countries.
Patrick Munk, Dongsheng Yang, Timo Röder, Leonie Maier, Thomas Nordahl Petersen, Ana Sofia Ribeiro Duarte, Philip T. L. C. Clausen, Christian Brinch, Liese Van Gompel, Roosmarijn Luiken, Jaap A. Wagenaar, Heike Schmitt, Dick J. J. Heederik, Dik J. Mevius, Lidwien A. M. Smit, Alex Bossers, Frank M. Aarestrup, Haitske Graveland, Bruno Gonzalez-Zorn, Gabriel Moyano, Pascal Sanders, Claire Chauvin, Antonio Battisti, Jeroen Dewulf, Katharina Wadepohl, Dariusz Wasyl, Magdalena Skarzyńska, Magdalena Zajac, Agnieszka Pękala-Safińska, Hristo Daskalov, Katharina D. C. Stärk   +30 more
openaire   +7 more sources

Cephem Potentiation by Inactivation of Nonessential Genes Involved in Cell Wall Biogenesis of ß-Lactamase-Producing Escherichia coli [PDF]

, 2017
Reversal of antimicrobial resistance is an appealing and largely unexplored strategy in drug discovery. The objective of this study was to identify potential targets for “helper” drugs reversing cephem resistance in Escherichia coli strains producing β ...
Baker, K R, Guardabassi, L, Jana, B, Sigurðardóttir, H H   +3 more
core   +2 more sources

From Lake Victoria to the Tap: Antibiotic Resistance and Pathogenic Contamination of Kisumu City Water Supply and Wastewater Network

Tropical Medicine &International Health, EarlyView.
ABSTRACT Waterborne diseases and antimicrobial resistance (AMR) pose mounting public health threats across sub‐Saharan Africa, particularly in rapidly urbanising regions dependent on untreated or poorly treated surface waters. This study applied shotgun metagenomic sequencing to characterise microbial communities, virulence factors and antibiotic ...
Oleg N. Reva, Anthony Sifuna, Francis Orata, Caroline Omolo, Jacob Stanley Iramiot, Mark C. Enright, Awelani Mutshembele, Jian Zhou, William A. Shivoga   +8 more
wiley   +1 more source