Results 61 to 70 of about 11,688 (211)

Bacteriophages as vehicles of the resistome in cystic fibrosis [PDF]

Journal of Antimicrobial Chemotherapy, 2011
Environmental microbial communities and human microbiota represent a huge reservoir of mobilizable genes, the 'mobilome', including a pool of genes encoding antimicrobial resistance, the 'resistome'. Whole-genome sequencing of bacterial genomes from cystic fibrosis (CF) patients has demonstrated that bacteriophages contribute significantly to bacterial
Rolain, Jean-Marc, Fancello, Laura, Desnues, Christelle, Raoult, Didier   +3 more
openaire   +4 more sources

Limited dissemination of the wastewater treatment plant core resistome [PDF]

, 2015
Horizontal gene transfer is a major contributor to the evolution of bacterial genomes and can facilitate the dissemination of antibiotic resistance genes between environmental reservoirs and potential pathogens.
Albertsen, Mads, Per Halkjær Nielsen, Ellabaan, Mostafa, Munck, Christian, Telke, Amar, Ellabaan, Mostafa M Hashim, Mads Albertsen, Morten O. A. Sommer, Nielsen, Per Halkjær, Christian Munck, Sommer, Morten Otto Alexander, Amar Telke, Mostafa Ellabaan, Albertsen, Mads; id_orcid, Sommer, Morten O. A.   +14 more
core   +1 more source

The intrinsic resistome of Klebsiella pneumoniae

International Journal of Antimicrobial Agents, 2019
Molecular epidemiology studies aiming at understanding the acquisition of antimicrobial resistance by clinical isolates of Klebsiella pneumoniae are regularly published; however, information on the genes that contribute to its characteristic phenotype of resistance to antibiotics (intrinsic resistome) is scarce. To fill this gap, a K.
Bernardini, Alejandra, Cuesta, Trinidad, Tomás, Anna, Bengoechea, José A., Martínez, José L., Sánchez, María B.   +5 more
openaire   +4 more sources

Validated predictive modelling of the environmental resistome [PDF]

The ISME Journal, 2015
Abstract Multi-drug-resistant bacteria pose a significant threat to public health. The role of the environment in the overall rise in antibiotic-resistant infections and risk to humans is largely unknown. This study aimed to evaluate drivers of antibiotic-resistance levels across the River Thames catchment, model key biotic, spatial ...
Amos, Gregory C.A., Gozzard, Emma, Carter, Charlotte E., Mead, Andrew, Bowes, Mike J., Hawkey, Peter M., Zhang, Lihong, Singer, Andrew C., Gaze, William H., Wellington, Elizabeth M.H.   +9 more
openaire   +5 more sources

Comprehensive genomic landscape of antibiotic resistance in Staphylococcus epidermidis

mSystems
Staphylococcus epidermidis, a common commensal bacterium found on human skin, can cause infections in clinical settings, and the presence of antibiotic resistance genes (ARGs) impedes the treatment of S. epidermidis infections.
Do-Hoon Lee, Kihyun Lee, Yong-Seok Kim, Chang-Jun Cha   +3 more
doaj   +1 more source

The Versatile Mutational Resistome of Pseudomonas aeruginosa [PDF]

Frontiers in Microbiology, 2018
One of the most striking features of Pseudomonas aeruginosa is its outstanding capacity for developing antimicrobial resistance to nearly all available antipseudomonal agents through the selection of chromosomal mutations, leading to the failure of the treatment of severe hospital-acquired or chronic infections.
Lopez-Causape, Carla; Cabot, Gabriel; del Barrio-Tofino, Ester; Oliver, Antonio   +4 more
openaire   +3 more sources

Snapshot of resistome, virulome and mobilome in aquaculture

Science of The Total Environment, 2023
Aquaculture environments can be hotspots for resistance genes through the surrounding environment. Our objective was to study the resistome, virulome and mobilome of Gram-negative bacteria isolated in seabream and bivalve molluscs, using a WGS approach.
Vanessa, Salgueiro, Vera, Manageiro, Tânia, Rosado, Narcisa M, Bandarra, Maria João, Botelho, Elsa, Dias, Manuela, Caniça   +6 more
openaire   +2 more sources

Long-Term Impact of Field Applications of Sewage Sludge on Soil Antibiotic Resistome

, 2016
Land applications of municipal sewage sludge may pose a risk of introducing antibiotic resistance genes (ARGs) from urban environments into agricultural systems. However, how the sewage sludge recycling and application method influence soil resistome and
Wan-Ying Xie, Qirong Shen, Xie, W-Y., Hirsch, P. R., Steve P. McGrath, Jian-Qiang Su (1584376), Zhao, F-J., Fang-Jie Zhao, Shen, Q., Jian-Qiang Su, Yong-Guan Zhu (1332507), Su, J. Q., Penny R. Hirsch, Ian M. Clark (3359321), Zhu, Y-G., Wan-Ying Xie (1762090), Penny R. Hirsch (324472), McGrath, S. P., Clark, I. M., Qirong Shen (404759), Yong-Guan Zhu, Steve P. McGrath (115749), Fang-Jie Zhao (146834), Ian M. Clark   +23 more
core   +1 more source

Cefquinome shows a higher impact on the pig gut microbiome and resistome compared to ceftiofur

Veterinary Research, 2023
Cephalosporins are licensed for treatment of severe bacterial infections in different species. However, the effect of these antimicrobials on the fecal microbiome and potential spread of resistance-associated genes causes great concern.
Sofie Rutjens, Nick Vereecke, Jannes Sauer, Siska Croubels, Mathias Devreese   +4 more
doaj   +1 more source

Geographic patterns and determinants of antibiotic resistomes in coastal sediments across complex ecological gradients

Frontiers in Microbiology, 2022
Coastal areas are highly influenced by terrestrial runoffs and anthropogenic disturbances, commonly leading to ecological gradients from bay, nearshore, to offshore areas.
Shangling Xiong, Shangling Xiong, Kai Wang, Kai Wang, Kai Wang, Huizhen Yan, Dandi Hou, Dandi Hou, Yanting Wang, Meng Li, Demin Zhang, Demin Zhang, Demin Zhang   +12 more
doaj   +1 more source