Results 61 to 70 of about 18,872 (210)
The European livestock resistome
mSystemsABSTRACT Metagenomic sequencing has proven to be a powerful tool in the monitoring of antimicrobial resistance (AMR). Here, we provide a comparative analysis of the resistome from pigs, poultry, veal calves, turkey, and rainbow trout, for a total of 538 herds across nine European countries.
Patrick Munk +30 more
openaire +7 more sources
Microbiome, 2020 Background Intestinal microbiota restoration can be achieved by complementing a subject’s perturbed microbiota with that of a healthy donor. Recurrent Clostridioides difficile infection (rCDI) is one key application of such treatment.
Suryang Kwak +11 more
doaj +1 more source
Antibiotics as selectors and accelerators 1 of diversity in the mechanisms of resistance: from the resistome to genetic plasticity in the β-lactamases world [PDF]
, 2013 Antibiotics and antibiotic resistance determinants, natural molecules closely related to bacterial physiology and consistent with an ancient origin, are not only present in antibiotic-producing bacteria.
Cantón, Rafael +3 more
core +3 more sources
L‐EasyARG: A long‐read metagenomics tool for rapid antibiotic‐resistance‐gene profiling
iMetaOmics, EarlyView.L‐EasyARG is a pipeline for long‐read metagenomic profiling of antibiotic resistance genes (ARGs) and their genetic context. It integrates ARG identification, plasmid and mobile genetic element (MGE) detection, taxonomic classification, and further identifies ARGs carried by human bacterial pathogens (HBPs) defined in the WHO and ESKAPE pathogen lists.
Yongxin Li +9 more
wiley +1 more source
The intrinsic resistome of Klebsiella pneumoniae
International Journal of Antimicrobial Agents, 2019 Molecular epidemiology studies aiming at understanding the acquisition of antimicrobial resistance by clinical isolates of Klebsiella pneumoniae are regularly published; however, information on the genes that contribute to its characteristic phenotype of resistance to antibiotics (intrinsic resistome) is scarce. To fill this gap, a K.
Bernardini, Alejandra +5 more
openaire +4 more sources
Mining the Antibiotic Resistome
Chemistry & Biology, 2012 Antibiotic-producing microoganisms are a reservoir of drug resistance genes. Studies of the "antibiotic resistome" can inform antimicrobial drug discovery and explain the emergence of multidrug resistant pathogens. In this issue of Chemistry & Biology, Westman and colleagues take an alternative look at the resistome and identify genes that could be ...
openaire +2 more sources
Unraveling the Amycolatopsis tucumanensis copper-resistome
BioMetals, 2012 Heavy metal pollution is widespread causing serious ecological problems in many parts of the world; especially in developing countries where a budget for remediation technology is not affordable. Therefore, screening for microbes with high accumulation capacities and studying their stable resistance characteristics is advisable to define cost-effective
Dávila Costa, José Sebastián +3 more
openaire +3 more sources
Microbiology ResearchAntibiotic resistance is a global health problem. The human gut microbiome is implicated in the dynamics of antibiotic resistance acquisition and transmission, with the gut microbiota thought to play a crucial role.
Justine Fri +3 more
doaj +1 more source
Population-level impacts of antibiotic usage on the human gut microbiome
Nature Communications, 2023 Here, the authors study the population-level impact of antimicrobial resistance genes (ARGs). By analyzing 8972 metagenomes and 3,096 gut microbiomes from healthy individuals not taking antibiotics, they demonstrate significant correlations between both ...
Kihyun Lee +8 more
doaj +1 more source
Gut Microbes, 2022 Antimicrobial resistance is a growing public health burden, but little is known about the effects of antibiotic exposure on the gut resistome. As childhood (0–5 years) represents a sensitive window of microbiome development and a time of relatively high ...
Rebecca M. Lebeaux +6 more
doaj +1 more source