Results 61 to 70 of about 19,820 (248)

Limited dissemination of the wastewater treatment plant core resistome [PDF]

, 2015
Horizontal gene transfer is a major contributor to the evolution of bacterial genomes and can facilitate the dissemination of antibiotic resistance genes between environmental reservoirs and potential pathogens.
Albertsen, Mads, Per Halkjær Nielsen, Ellabaan, Mostafa, Munck, Christian, Telke, Amar, Ellabaan, Mostafa M Hashim, Mads Albertsen, Morten O. A. Sommer, Nielsen, Per Halkjær, Christian Munck, Sommer, Morten Otto Alexander, Amar Telke, Mostafa Ellabaan, Albertsen, Mads; id_orcid, Sommer, Morten O. A.   +14 more
core   +1 more source

Bacteriophages as vehicles of the resistome in cystic fibrosis [PDF]

Journal of Antimicrobial Chemotherapy, 2011
Environmental microbial communities and human microbiota represent a huge reservoir of mobilizable genes, the 'mobilome', including a pool of genes encoding antimicrobial resistance, the 'resistome'. Whole-genome sequencing of bacterial genomes from cystic fibrosis (CF) patients has demonstrated that bacteriophages contribute significantly to bacterial
Rolain, Jean-Marc, Fancello, Laura, Desnues, Christelle, Raoult, Didier   +3 more
openaire   +4 more sources

Destination shapes antibiotic resistance gene acquisitions, abundance increases, and diversity changes in Dutch travelers

Genome Medicine, 2021
Background Antimicrobial-resistant bacteria and their antimicrobial resistance (AMR) genes can spread by hitchhiking in human guts. International travel can exacerbate this public health threat when travelers acquire AMR genes endemic to their ...
Alaric W. D’Souza, Manish Boolchandani, Sanket Patel, Gianluca Galazzo, Jarne M. van Hattem, Maris S. Arcilla, Damian C. Melles, Menno D. de Jong, Constance Schultsz, COMBAT Consortium, Gautam Dantas, John Penders   +11 more
doaj   +1 more source

Environmental and Anthropogenic Factors Shape the Snow Microbiome and Antibiotic Resistome

Frontiers in Microbiology, 2022
Winter tourism can generate environmental pollution and affect microbial ecology in mountain ecosystems. This could stimulate the development of antibiotic resistance in snow and its dissemination through the atmosphere and through snow melting.
Concepcion Sanchez-Cid, Concepcion Sanchez-Cid, Christoph Keuschnig, Karol Torzewski, Łukasz Stachnik, Daniel Kępski, Bartłomiej Luks, Adam Nawrot, Adam Nawrot, Przemysław Niedzielski, Timothy M. Vogel, Catherine Larose   +11 more
doaj   +1 more source

Validated predictive modelling of the environmental resistome [PDF]

The ISME Journal, 2015
Abstract Multi-drug-resistant bacteria pose a significant threat to public health. The role of the environment in the overall rise in antibiotic-resistant infections and risk to humans is largely unknown. This study aimed to evaluate drivers of antibiotic-resistance levels across the River Thames catchment, model key biotic, spatial ...
Amos, Gregory C.A., Gozzard, Emma, Carter, Charlotte E., Mead, Andrew, Bowes, Mike J., Hawkey, Peter M., Zhang, Lihong, Singer, Andrew C., Gaze, William H., Wellington, Elizabeth M.H.   +9 more
openaire   +5 more sources

Comprehensive genomic landscape of antibiotic resistance in Staphylococcus epidermidis

mSystems
Staphylococcus epidermidis, a common commensal bacterium found on human skin, can cause infections in clinical settings, and the presence of antibiotic resistance genes (ARGs) impedes the treatment of S. epidermidis infections.
Do-Hoon Lee, Kihyun Lee, Yong-Seok Kim, Chang-Jun Cha   +3 more
doaj   +1 more source

Global soil antibiotic resistance genes are associated with increasing risk and connectivity to human resistome

Nature Communications
Soil is a reservoir of antibiotic resistance genes (ARGs), and understanding its connection to human antibiotic resistome is crucial for the One Health framework.
Yuxiang Zhao, Li-Guan Li, Yue Huang, Xiao-Qing Xu, Zi-Shu Liu, Shuxian Li, Li-Zhong Zhu, Baolan Hu, Tong Zhang   +8 more
semanticscholar   +1 more source

The oral microbiota is a reservoir for antimicrobial resistance: resistome and phenotypic resistance characteristics of oral biofilm in health, caries, and periodontitis

Annals of Clinical Microbiology and Antimicrobials, 2023
Background Antimicrobial resistance (AMR) is an ever-growing threat to modern medicine and, according to the latest reports, it causes nearly twice as many deaths globally as AIDS or malaria.
A. Anderson, C. von Ohle, C. Frese, S. Boutin, C. Bridson, K. Schoilew, S. A. Peikert, E. Hellwig, K. Pelz, A. Wittmer, D. Wolff, A. Al-Ahmad   +11 more
semanticscholar   +1 more source

The Versatile Mutational Resistome of Pseudomonas aeruginosa [PDF]

Frontiers in Microbiology, 2018
One of the most striking features of Pseudomonas aeruginosa is its outstanding capacity for developing antimicrobial resistance to nearly all available antipseudomonal agents through the selection of chromosomal mutations, leading to the failure of the treatment of severe hospital-acquired or chronic infections.
Lopez-Causape, Carla; Cabot, Gabriel; del Barrio-Tofino, Ester; Oliver, Antonio   +4 more
openaire   +3 more sources

Global health risks lurking in livestock resistome

Science Advances
Livestock farming consumes more than 70% of global antibiotics annually, making livestock manures an important vector of anthropogenically influenced antibiotic resistance genes (ARGs).
Bin-Tao Li, Lan Jiang, T. Johnson, Guang-Dong Wang, Wei Sun, Gehong Wei, Shuo Jiao, Jie Gu, J. Tiedje, Xun Qian   +9 more
semanticscholar   +1 more source