Results 61 to 70 of about 11,619 (200)

Comprehensive genomic landscape of antibiotic resistance in Staphylococcus epidermidis

mSystems
Staphylococcus epidermidis, a common commensal bacterium found on human skin, can cause infections in clinical settings, and the presence of antibiotic resistance genes (ARGs) impedes the treatment of S. epidermidis infections.
Do-Hoon Lee, Kihyun Lee, Yong-Seok Kim, Chang-Jun Cha   +3 more
doaj   +1 more source

Global soil antibiotic resistance genes are associated with increasing risk and connectivity to human resistome

Nature Communications
Soil is a reservoir of antibiotic resistance genes (ARGs), and understanding its connection to human antibiotic resistome is crucial for the One Health framework.
Yuxiang Zhao, Liguan Li, Yue Huang, Xiao-Qing Xu, Zi-Shu Liu, Shuxian Li, Lizhong Zhu, Baolan Hu, Tong Zhang   +8 more
semanticscholar   +1 more source

Global health risks lurking in livestock resistome

Science Advances
Livestock farming consumes more than 70% of global antibiotics annually, making livestock manures an important vector of anthropogenically influenced antibiotic resistance genes (ARGs).
Bintao Li, Lan Jiang, T. Johnson, Guangdong Wang, Wei Sun, Gehong Wei, Shuo Jiao, Jie Gu, J. Tiedje, Xun Qian   +9 more
semanticscholar   +1 more source

Long-Term Impact of Field Applications of Sewage Sludge on Soil Antibiotic Resistome

, 2016
Land applications of municipal sewage sludge may pose a risk of introducing antibiotic resistance genes (ARGs) from urban environments into agricultural systems. However, how the sewage sludge recycling and application method influence soil resistome and
Wan-Ying Xie, Qirong Shen, Xie, W-Y., Hirsch, P. R., Steve P. McGrath, Jian-Qiang Su (1584376), Zhao, F-J., Fang-Jie Zhao, Shen, Q., Jian-Qiang Su, Yong-Guan Zhu (1332507), Su, J. Q., Penny R. Hirsch, Ian M. Clark (3359321), Zhu, Y-G., Wan-Ying Xie (1762090), Penny R. Hirsch (324472), McGrath, S. P., Clark, I. M., Qirong Shen (404759), Yong-Guan Zhu, Steve P. McGrath (115749), Fang-Jie Zhao (146834), Ian M. Clark   +23 more
core   +1 more source

Carbapenem-Resistant Pseudomonas aeruginosa’s Resistome: Pan-Genomic Plasticity, the Impact of Transposable Elements and Jumping Genes

Antibiotics
Pseudomonas aeruginosa, a Gram-negative, motile bacterium, may cause significant infections in both community and hospital settings, leading to substantial morbidity and mortality. This opportunistic pathogen can thrive in various environments, making it
T. Karampatakis, K. Tsergouli, P. Behzadi   +2 more
semanticscholar   +1 more source

uCARE Chem Suite and uCAREChemSuiteCLI: Tools for bacterial resistome prediction

, 2021
In the era of antibiotic resistance, in silico prediction of bacterial resistome profiles, likely to be associated with inactivation of new potential antibiotics is of utmost importance. Despite this, to the best of our knowledge, no tool exists for such
Vijai Kumar Gupta, Saurav Bhaskar Saha, Pramod Wasudeo Ramteke   +2 more
core   +1 more source

Population-level impacts of antibiotic usage on the human gut microbiome

Nature Communications, 2023
Here, the authors study the population-level impact of antimicrobial resistance genes (ARGs). By analyzing 8972 metagenomes and 3,096 gut microbiomes from healthy individuals not taking antibiotics, they demonstrate significant correlations between both ...
Kihyun Lee, Sebastien Raguideau, Kimmo Sirén, Francesco Asnicar, Fabio Cumbo, Falk Hildebrand, Nicola Segata, Chang-Jun Cha, Christopher Quince   +8 more
doaj   +1 more source

Climate warming fuels the global antibiotic resistome by altering soil bacterial traits

Nature Ecology & Evolution
Understanding the implications of global warming on the spread of antibiotic resistance genes (ARGs) and virulence factor genes (VFGs) within soil ecosystems is crucial for safeguarding human well-being and sustaining ecosystem health.
Da Lin, Shuai Du, Zhe Zhao, Tian-Lun Zhang, Lu Wang, Qi Zhang, Shu-Yi-Dan Zhou, David W. Graham, D. Tissue, Dong Zhu, Yong-Guan Zhu, Josep Peňuelas, P. Reich   +12 more
semanticscholar   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

Metagenomic and culture‐based insights into host and plasmid contexts of high‐risk ARGs in poultry farm environments

iMetaOmics, EarlyView.
Shotgun metagenomics and culture‐based isolate genomics revealed position‐associated high‐risk antibiotic resistance genes (ARGs) signals across poultry manure piles and surrounding soils. Culture‐confirmed Enterobacteriaceae and IncHI2A‐related blaNDM‐5 plasmid backgrounds further highlight priority host‐ARG‐plasmid contexts for farm antimicrobial ...
Yaling Wang, Lianwei Ye, Linan He, Zhenlong Wu, Yiwen Yang, Sheng Chen   +5 more
wiley   +1 more source