Results 51 to 60 of about 11,688 (211)

Rapid resistome mapping using nanopore sequencing [PDF]

, 2017
The emergence of antibiotic resistance in human pathogens has become a major threat to modern medicine. The outcome of antibiotic treatment can be affected by the composition of the gut.
Hashim Ellabaan, Mostafa M, van der Helm, Eric, van Schaik, Willem, Sommer, Morten Otto Alexander, Ellabaan, Mostafa M Hashim, Koza, Anna, Sommer, Morten O A, Imamovic, Lejla, van Schaik, Willem; id_orcid   +8 more
core   +1 more source

The human gut resistome [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2015
In recent decades, the emergence and spread of antibiotic resistance among bacterial pathogens has become a major threat to public health. Bacteria can acquire antibiotic resistance genes by the mobilization and transfer of resistance genes from a donor strain.
openaire   +2 more sources

Environmental and Anthropogenic Factors Shape the Snow Microbiome and Antibiotic Resistome

Frontiers in Microbiology, 2022
Winter tourism can generate environmental pollution and affect microbial ecology in mountain ecosystems. This could stimulate the development of antibiotic resistance in snow and its dissemination through the atmosphere and through snow melting.
Concepcion Sanchez-Cid, Concepcion Sanchez-Cid, Christoph Keuschnig, Karol Torzewski, Łukasz Stachnik, Daniel Kępski, Bartłomiej Luks, Adam Nawrot, Adam Nawrot, Przemysław Niedzielski, Timothy M. Vogel, Catherine Larose   +11 more
doaj   +1 more source

In-depth resistome analysis by targeted metagenomics [PDF]

Microbiome, 2017
ABSTRACT We developed ResCap, a targeted sequence capture platform based on SeqCapEZ technology, to analyse resistomes and other genes related to antimicrobial resistance (heavy metals, biocides and plasmids). ResCap includes probes for 8,667 canonical resistance genes (7,963 antibiotic resistance genes and 704 genes conferring ...
Lanza, Val F., Baquero, Fernando, Martinez, Jose Luis, Ramos-Ruíz, Ricardo, Gonzalez-Zorn, Bruno, Andremont, Antoine, Sánchez-Valenzuela, Antonio, Ehrlich, Stanislav Dusko, Kennedy, Sean, Ruppe, Etienne, van Schaik, Willem, Willems, Rob J., de La Cruz, Fernando, Coque, Teresa M.   +13 more
openaire   +9 more sources

SNAP2 datasets for the Resistome

, 2020
SNAP2 datasets for the Resistome; these are varient effect predictions for most of the proteome. Files should be placed under inputs/protein_predictions according the instructions provided on the Resistome repo website.
Winkler, James
core   +1 more source

Effects of Probiotic Supplementation on the Gut Microbiota and Antibiotic Resistome Development in Preterm Infants [PDF]

, 2018
Objectives: In 2014 probiotic supplementation (Lactobacillus acidophilus and Bifidobacterium longum subspecies infantis; Infloran®) was introduced as standard of care to prevent necrotizing enterocolitis (NEC) in extremely preterm infants in Norway.
Pedersen, Tanja, Willassen, Nils Peder, Esaiassen, Eirin, Rettedal, Siren, Støen, Ragnhild, Hjerde, Erik, Nakstad, Britt, Klingenberg, Claus, Cavanagh, Jorunn Pauline, Andresen, Jannicke Hanne   +9 more
core   +1 more source

Host genetic and environmental factors shape the human gut resistome [PDF]

, 2020
BACKGROUND: Understanding and controlling the spread of antimicrobial resistance is one of the greatest challenges of modern medicine. To this end many efforts focus on characterising the human resistome or the set of antibiotic resistance determinants ...
Costeira, R., Martin, T.C., Le Roy, C.I., Carr, V.R., Steves, C., Forslund, S.K., Spector, T., Bell, J.T., Bowyer, R.C.E., Castillo-Fernandez, J.E.R., Moyes, D.   +10 more
core   +1 more source

PRAP: Pan Resistome analysis pipeline [PDF]

BMC Bioinformatics, 2020
Abstract Background Antibiotic resistance genes (ARGs) can spread among pathogens via horizontal gene transfer, resulting in imparities in their distribution even within the same species. Therefore, a pan-genome approach to analyzing resistomes is necessary for thoroughly characterizing patterns of ARGs distribution within particular pathogen ...
Yichen He, Xiujuan Zhou, Ziyan Chen, Xiangyu Deng, Andrew Gehring, Hongyu Ou, Lida Zhang, Xianming Shi   +7 more
openaire   +3 more sources

Destination shapes antibiotic resistance gene acquisitions, abundance increases, and diversity changes in Dutch travelers

Genome Medicine, 2021
Background Antimicrobial-resistant bacteria and their antimicrobial resistance (AMR) genes can spread by hitchhiking in human guts. International travel can exacerbate this public health threat when travelers acquire AMR genes endemic to their ...
Alaric W. D’Souza, Manish Boolchandani, Sanket Patel, Gianluca Galazzo, Jarne M. van Hattem, Maris S. Arcilla, Damian C. Melles, Menno D. de Jong, Constance Schultsz, COMBAT Consortium, Gautam Dantas, John Penders   +11 more
doaj   +1 more source

Social demographics determinants for resistome and microbiome variation of a multiethnic community in Southern Malaysia

npj Biofilms and Microbiomes, 2023
The prevalence of antibiotic-resistant bacteria in Southeast Asia is a significant concern, yet there is limited research on the gut resistome and its correlation with lifestyle and environmental factors in the region. This study aimed to profile the gut
J. Dwiyanto, M. A. L. Huët, M. H. Hussain, T. T. Su, J. B. L. Tan, K. Y. Toh, J. W. J. Lee, S. Rahman, C. W. Chong   +8 more
doaj   +1 more source