Results 71 to 80 of about 11,619 (200)

Cefquinome shows a higher impact on the pig gut microbiome and resistome compared to ceftiofur

Veterinary Research, 2023
Cephalosporins are licensed for treatment of severe bacterial infections in different species. However, the effect of these antimicrobials on the fecal microbiome and potential spread of resistance-associated genes causes great concern.
Sofie Rutjens, Nick Vereecke, Jannes Sauer, Siska Croubels, Mathias Devreese   +4 more
doaj   +1 more source

The tetracycline resistome is shaped by selection for specific resistance mechanisms by each antibiotic generation

Nature Communications
The history of clinical resistance to tetracycline antibiotics is characterized by cycles whereby the deployment of a new generation of drug molecules is quickly followed by the discovery of a new mechanism of resistance. This suggests mechanism-specific
Kevin S. Blake, Yao-Peng Xue, V. Gillespie, S. Fishbein, N. Tolia, T. Wencewicz, G. Dantas   +6 more
semanticscholar   +1 more source

Antibiotic resistome from the One-Health perspective: understanding and controlling antimicrobial resistance transmission

Experimental and Molecular Medicine, 2021
The concept of the antibiotic resistome was introduced just over a decade ago, and since then, active resistome studies have been conducted. In the present study, we describe the previously established concept of the resistome, which encompasses all ...
Dae-Wi Kim, C. Cha
semanticscholar   +1 more source

Tetracycline Resistome of the Organic Pig Gut [PDF]

Applied and Environmental Microbiology, 2009
ABSTRACT The occurrence of genes conferring resistance to tetracyclines in the organic pig gut was assessed through the metagenomic approach. Of 9,000 bacterial artificial chromosome clones analyzed, 10 were identified as carrying the known tet (C), tet (W), and tet
Katarzyna A, Kazimierczak, Karen P, Scott, Denise, Kelly, Rustam I, Aminov   +3 more
openaire   +2 more sources

The Antibiotic Resistance ‘Mobilome’: searching for the link between environment and clinic.

Frontiers in Microbiology, 2013
Antibiotic resistance is an ancient problem, owing to the co-evolution of antibiotic-producing and target organisms in the soil and other environments over millennia.
Julie ePerry, Julie ePerry, Gerard eWright, Gerard eWright   +3 more
doaj   +1 more source

Perinatal risk factors for fecal antibiotic resistance gene patterns in pregnant women and their infants.

PLoS ONE, 2020
Perinatal factors can shape fecal microbiome patterns among pregnant women and their infants. However, there is scarce information about the effect of maternal demographics and perinatal exposures on antibiotic resistance genes (ARG) and mobile genetic ...
Andrea Sosa-Moreno, Sarah S Comstock, Kameron Y Sugino, Teng F Ma, Nigel Paneth, Yelena Davis, Rosemary Olivero, Rebecca Schein, Joel Maurer, Lixin Zhang   +9 more
doaj   +1 more source

Impact of early life antibiotic and probiotic treatment on gut microbiome and resistome of very-low-birth-weight preterm infants

bioRxiv
Preterm infants (300 metagenome- assembled genomes, and obtained ∼90 isolate genomes through targeted culturomics, enabling analysis of the microbiome/resistome at species and strain levels. Additionally, we investigated in vitro horizontal gene transfer
R. Kiu, Elizabeth M. Darby, Cristina Alcon-Giner, Antia Acuna-Gonzalez, Anny Camargo, Lisa E. Lamberte, Sarah Phillips, K. Sim, A. Shaw, P. Clarke, W. van Schaik, J. Kroll, L. Hall   +12 more
semanticscholar   +1 more source

The oral microbiota is a reservoir for antimicrobial resistance: resistome and phenotypic resistance characteristics of oral biofilm in health, caries, and periodontitis

Annals of Clinical Microbiology and Antimicrobials, 2023
Background Antimicrobial resistance (AMR) is an ever-growing threat to modern medicine and, according to the latest reports, it causes nearly twice as many deaths globally as AIDS or malaria.
A. Anderson, C. von Ohle, C. Frese, S. Boutin, C. Bridson, K. Schoilew, S. A. Peikert, E. Hellwig, K. Pelz, A. Wittmer, D. Wolff, A. Al-Ahmad   +11 more
semanticscholar   +1 more source

Cotton Farming Pesticides Affect Ileal Microbiota Activity and Expression of Virulome but Not Resistome or Metabolic Pathways in a Sedentary Wild Passerine

Environmental Toxicology, EarlyView.
ABSTRACT The increased use of agrochemicals to enhance crop production has had detrimental environmental effects including implication in the sharp decline of North American farmland‐breeding birds. Here, using a combination of deep shotgun metatranscriptomics and pesticide exposure data, we sought to assess whether exposure to cotton (Gossypium spp ...
Serguei V. Drovetski, Michelle L. Hladik, Carolina F. Ferreira, Dana W. Kolpin, Gary Voelker   +4 more
wiley   +1 more source

Snapshot of resistome, virulome and mobilome in aquaculture

Science of The Total Environment, 2023
Aquaculture environments can be hotspots for resistance genes through the surrounding environment. Our objective was to study the resistome, virulome and mobilome of Gram-negative bacteria isolated in seabream and bivalve molluscs, using a WGS approach.
Vanessa, Salgueiro, Vera, Manageiro, Tânia, Rosado, Narcisa M, Bandarra, Maria João, Botelho, Elsa, Dias, Manuela, Caniça   +6 more
openaire   +2 more sources