Results 61 to 70 of about 675,824 (339)

Microarray analyses demonstrate the involvement of type i interferons in psoriasiform pathology development in D6-deficient mice [PDF]

, 2013
The inflammatory response is normally limited by mechanisms regulating its resolution. In the absence of resolution, inflammatory pathologies can emerge, resulting in substantial morbidity and mortality.
Baldwin, H.M., Carballido, J.M., Graham, G.J., Jamieson, T., Jaritz, M., King, V., McKimmie, C.S., Nibbs, R.J.B., Pallas, K., Rot, A.   +9 more
core   +1 more source

Resolution of Heart Failure Inflammation

JACC: Basic to Translational Science, 2022
[Figure: see text]
openaire   +2 more sources

Vagus nerve controls resolution and pro-resolving mediators of inflammation [PDF]

, 2015
Resolution of inflammation is now recognized as a biosynthetically active process involving pro-resolving mediators. Here, we show in zymosan-initiated peritoneal inflammation that the vagus nerve regulates local expression of netrin-1, an axonal ...
Dalli, Jesmond, Granja, Tiago, Mirakaj, Valbona, Rosenberger, Peter, Serhan, Charles N.   +4 more
core   +1 more source

Specialized Pro-Resolving Mediators as Potential Regulators of Inflammatory Macrophage Responses in COVID-19

Frontiers in Immunology, 2021
The recent outbreak of SARS-CoV2 has emerged as one of the biggest pandemics of our century, with outrageous health, social and economic consequences globally.
Maria G. Balta, Evangelos Papathanasiou, Evangelos Papathanasiou, Panagiotis F. Christopoulos   +3 more
doaj   +1 more source

GSK3: A Kinase Balancing Promotion and Resolution of Inflammation

Cells, 2020
GSK3 has been implicated for years in the regulation of inflammation and addressed in a plethora of scientific reports using a variety of experimental (disease) models and approaches.
Leonie Hoffmeister, M. Diekmann, K. Brand, René Huber   +3 more
semanticscholar   +1 more source

New Advances in Targeting the Resolution of Inflammation: Implications for Specialized Pro-Resolving Mediator GPCR Drug Discovery.

ACS Pharmacology & Translational Science, 2020
Chronic inflammation is a component of numerous diseases including autoimmune, metabolic, neurodegenerative, and cancer. The discovery and characterization of specialized pro-resolving mediators (SPMs) critical to the resolution of inflammation, and ...
Julia Park, C. Langmead, Darren M. Riddy
semanticscholar   +1 more source

Steroids in pediatric eosinophilic esophagitis [PDF]

, 2014
Swallowed fluticasone and oral viscous budesonide are effective first-line therapies for eosinophilic esophagitis in children. Side effects are minimal without evidence of Cushing syndrome, as seen in treatment with systemic corticosteroids.
Contreras, Emily M., Gupta, Sandeep K.
core   +1 more source

TRPV4-A Missing Link Between Mechanosensation and Immunity [PDF]

, 2020
Transient receptor potential vanilloid-type 4 (TRPV4) cation channel is widely expressed in all tissues as well as in immune cells and its function as mechanosensitive Ca2+ channel seems to be conserved throughout all mammalian species. Of late, emerging
Kuebler, Wolfgang M., Michalick, Laura
core   +1 more source

Apoptosis in resolution of inflammation [PDF]

Journal of Leukocyte Biology, 1997
Abstract The last few years have seen the accumulation of compelling evidence that apoptosis (programmed cell death) plays a major role in promoting resolution of the acute inflammatory response. Neutrophils are constitutively programmed to undergo apoptosis, which limits their pro-inflammatory potential and leads to rapid, specific, and
openaire   +3 more sources

Novel Resolution Mediators of Severe Systemic Inflammation

ImmunoTargets and Therapy, 2020
Verena Gudernatsch, Sylwia Anna Stefańczyk, Valbona Mirakaj Molecular Intensive Care Medicine, Department of Anesthesiology and Intensive Care Medicine, University Hospital Tübingen, Eberhard Karls University Tübingen, Tübingen ...
Gudernatsch V, Stefańczyk SA, Mirakaj V
doaj