Results 111 to 120 of about 29,973 (286)

Computing the resolvent of composite operators [PDF]

open access: yesCubo (Temuco), 2014
Summary: Based in a very recent paper by \textit{C. A. Micchelli} et al. [Adv. Comput. Math. 38, No. 2, 401--426 (2013; Zbl 1275.65014)], we present an algorithmic approach for computing the resolvent of composite operators: the composition of a monotone operator and a continuous linear mapping.
openaire   +5 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Dirichlet problem for second-order abstract differential equations

open access: yesElectronic Journal of Differential Equations, 2020
We study the well-posedness in the space of continuous functions of the Dirichlet boundary value problem for a homogeneous linear second-order differential equation u''+Au = 0, where A is a linear closed densely defined operator in a Banach space. We
Giovanni Dore
doaj  

An inverse problem for a second-order differential equation in a Banach space

open access: yesAbstract and Applied Analysis, 2004
We consider the problem of determining the unknown term in the right-hand side of a second-order differential equation with unbounded operator generating a cosine operator function from the overspecified boundary data.
Y. Eidelman
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Asymptotic stability of fractional impulsive neutral stochastic partial integro-differential equations with state-dependent delay

open access: yesElectronic Journal of Differential Equations, 2013
In this article, we study the asymptotical stability in p-th moment of mild solutions to a class of fractional impulsive partial neutral stochastic integro-differential equations with state-dependent delay in Hilbert spaces.
Zuomao Yan, Hongwu Zhang
doaj  

Global Hypoellipticity and Compactness of Resolvent for Fokker-Planck Operator

open access: yes, 2009
In this paper we study the Fokker-Planck operator with potential V(x), and analyze some kind of conditions imposed on the potential to ensure the validity of global hypoelliptic estimates.
Li, Wei-Xi
core   +1 more source

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