Results 51 to 60 of about 4,036,910 (348)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Feasibility and optimal imaging time window for intraperitoneal versus intravenous injection of a macrocyclic gadolinium-based contrast agent in mice

open access: yesJournal of International Medical Research
Objective This study aimed to evaluate the feasibility of intraperitoneal injection as an alternative to the technically challenging intravenous route for contrast agent administration in murine brain magnetic resonance imaging by comparing their ...
Mingyuan He   +6 more
doaj   +1 more source

Vibrational resonance [PDF]

open access: yesJournal of Physics A: Mathematical and General, 2000
Summary: The effect of a high-frequency force on the response of a bistable system to a low-frequency signal is considered for both the overdamped and weakly damped cases. It is shown that the response can be optimized by an appropriate choice of vibration amplitude.
Landa, P. S., McClintock, Peter V. E.
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Gelatinous Transformation of Bone Marrow Mimicking Malignant Marrow-Replacing Lesion on Magnetic Resonance Imaging in a Patient without Underlying Devastating Disease [PDF]

open access: yes, 2018
Gelatinous transformation of bone marrow is characterized by hypoplasia of fat cells with focal loss of hematopoietic cells and deposition of extracellular gelatinous substances.
유연화   +3 more
core   +1 more source

LISA improves statistical analysis for fMRI

open access: yesNature Communications, 2018
Functional magnetic resonance imaging (fMRI) is a powerful technique for measuring human brain activity, but the statistical analysis of fMRI data can be difficult.
Gabriele Lohmann   +7 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Hadron resonance production and final state hadronic interactions with UrQMD at LHC

open access: yes, 2015
We discuss the effects of the final hadronic state, in ultra-relativistic nuclear collisions, on hadronic resonance properties and measurable production rates. In particular we will compare our results with recent ALICE data on resonance production.
J. Steinheimer   +3 more
core   +1 more source

Overstability and resonance [PDF]

open access: yesAnnales de l'Institut Fourier, 2003
We consider a singularity perturbed nonlinear differential equation ε u ′ = f
Fruchard, Augustin, Schäfke, Reinhard
openaire   +2 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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