Polarization Engineering in Vinylene‐Linked COFs Toward Efficient Neuromorphic Computing
Advanced Science, EarlyView.A vinyl‐linked covalent organic framework (COF‐DIBPY) was synthesized on a conductive substrate for memristor applications. Redox reactions and bromide migration enable low‐voltage (0.5V) conductance switching with high analog on/off ratio (15.7). The device was further integrated into a speech emotion recognition system for acoustic simulation and ...
Hao Wang +5 more
wiley +1 more source
Chiral Nonlinear Enhancement with Opposite Circular Dichroism Empowered by Dual Bound States in the Continuum. [PDF]
Materials (Basel)Liu X, Wang L, Meng H.
europepmc +1 more source
A Universal Protein Ladder for Standardization of Diverse FRET Assays
Advanced Science, EarlyView.Translating FRET measurements from in vitro to intracellular environments requires universal benchmarks. We present a modular protein ladder using TPR motifs to harmonize data across diverse platforms. This predictable calibration curve bridges single molecule FRET measurements, with cell based measurements including FLIM‐FRET.
Evelyn R. Smith +5 more
wiley +1 more source
Reflective broadband adaptive optics scanning light ophthalmoscope with 20 D focus range. [PDF]
Biomed Opt ExpressSteven S, Xia Y, Bentley J, Dubra A.
europepmc +1 more source
Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance
Advanced Science, EarlyView.Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer +9 more
wiley +1 more source
Phase Control Mechanisms in Metasurfaces: From Static Approaches to Active and Space-Time Modulation. [PDF]
Sensors (Basel)Haroon M, Kim SW, Choi DY.
europepmc +1 more source
Advanced Science, EarlyView.This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang +11 more
wiley +1 more source
Experimental investigation of dynamic shear stiffness and damping ratio characteristics of marine soils in Lingdingyang Bay, China. [PDF]
Sci RepWu Y, Qin B, Fu Y, Wu Q.
europepmc +1 more source
Advanced Science, EarlyView.Inspired by the intricate microstructure of cicada wings, researchers developed a novel in situ skeleton‐graphene membrane architecture within lightweight foams. This bioinspired design dramatically enhances multifunctional performance: vibration attenuation time decreases by ∼83.3%, damping capacity increases by ∼179.3%, and compressive modulus rises ...
Jigang Feng +6 more
wiley +1 more source
Nonintrusive Dynamic Pressure Monitoring of Sloshing Liquid Using a Hierarchically Microstructured Flexible Sensor. [PDF]
LangmuirThapa P, Sarma S.
europepmc +1 more source