Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu +15 more
wiley +1 more source
Moth-Wing-Inspired Multifunctional Metamaterials. [PDF]
Pei H +12 more
europepmc +1 more source
A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng +16 more
wiley +1 more source
Atomic Tuning of Metal‐Support Interactions for Pathway‐Selective CO2 Photoreduction on TiO2
Single‐atom Fe and Cu catalysts anchored on TiO2 steer photocatalytic CO2 reduction toward distinct pathways. Fe sites favor rapid *CO desorption and selective CO formation, whereas Cu sites stabilize *CHO intermediates, enabling deep reduction and C─C coupling. Combined spectroscopy and DFT calculations reveal how metal–support interactions and oxygen
Dongyun Kim +13 more
wiley +1 more source
Robust resonant anomaly detection with NPLM. [PDF]
Grosso G +3 more
europepmc +1 more source
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci +13 more
wiley +1 more source
Dispersion Engineering and Sensitivity Enhancement in Photonic Crystal Waveguide Sensors: Current Advances and Emerging Challenges. [PDF]
Kazanskiy NL +2 more
europepmc +1 more source
Transfer printing micro-assembly of silicon photonic crystal cavity arrays: beating the fabrication tolerance limit. [PDF]
Bommer SP +7 more
europepmc +1 more source
Color-Filter-Free Image Sensor Using CsPbBr<sub>3</sub> Quantum-Dot-Based Tamm Plasmon Photodetector for Photonic Synapse Facial Recognition. [PDF]
Yen MC +11 more
europepmc +1 more source
Multi-state detection and spatial addressing in a microscope for ultracold molecules. [PDF]
Mortlock JM +4 more
europepmc +1 more source

