Results 61 to 70 of about 107,398 (297)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

ML-Driven Decision Support for Dynamic Modeling of Calcareous Sands

open access: yesMachine Learning and Knowledge Extraction
Dynamic characterization of calcareous (carbonate) sands is essential for performance-based design of offshore foundations, coastal reclamation, and marine infrastructure in tropical and subtropical regions.
Abdalla Y. Almarzooqi   +3 more
doaj   +1 more source

Experimental study on dynamic shear modulus and damping ratio of calcareous sands in the South China Sea

open access: yesYantu gongcheng xuebao, 2019
The dynamic shear modulus and damping ratio are two important parameters for the dynamic stability analysis of geotechnical structures and offshore sites.
LIU Xin 1, LI Sa 1, LIU Xiao-long 2, CHEN Wen-wei 2
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The Modified “Stiffened” Drnevich Resonant Column Apparatus

open access: yesSoils and Foundations, 1990
The original Drnevich Resonant Column apparatus has been designed for testing cylindrical soil specimens with maximum longitudinal and torsional stiffnesses corresponding to approximate resonant frequencies 285 Hz and 318 Hz, respectively. This apparatus has been modified successfully and its stiffness has been increased to over threefold in the ...
Anestis S. Avramidis, Surendra K. Saxena
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Small Strain Shear Modulus of the Ljubljana Marsh Soil Measured with Resonant Column and Bender Elements under Isotropic and Anisotropic Stress Conditions

open access: yesApplied Sciences
The increasing use of finite element analysis in modern infrastructure design emphasizes the importance of determining soil stiffness at small strains.
Timotej Jurček   +2 more
doaj   +1 more source

The Evaluation of the Initial Shear Modulus of Selected Cohesive Soils

open access: yesStudia Geotechnica et Mechanica, 2015
The paper concerns the evaluation of the initial stiffness of selected cohesive soils based on laboratory tests. The research materials used in this study were clayey soils taken from the area of the road embankment No.
Gabryś Katarzyna, Szymański Alojzy
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Resonance in a Cone-Topped Tube

open access: yesInternational Scholastic Journal of Science, 2011
The relationship between ratio of the upper opening diameter of a cone-topped cylinder to the cylinder diameter,and the ratio of the length of the air column to resonant period was examined. Plastic cones with upper openings ranging from 1.3 cm to 3.6 cm
Angus Cheng-Huan Chia   +1 more
doaj  

Home - About - Disclaimer - Privacy