Results 111 to 120 of about 9,284,406 (331)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Estimation of the Motion-Induced Horizontal-Wind-Speed Standard Deviation in an Offshore Doppler Lidar

open access: yesRemote Sensing, 2018
This work presents a new methodology to estimate the motion-induced standard deviation and related turbulence intensity on the retrieved horizontal wind speed by means of the velocity-azimuth-display algorithm applied to the conical scanning pattern of a
Miguel A. Gutiérrez-Antuñano   +3 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Photothermal conversion and geochemical characterization of sulfur-rich lignite for non-conventional energy applications

open access: yesScientific Reports
Lignite has emerged as a critical material in contemporary energy portfolios, particularly in electricity generation. However, this work explores lignite’s potential beyond conventional uses, exploring on its energy conversion applications.
P. Gopinathan   +11 more
doaj   +1 more source

ASSESSING IMPACTS OF ENVIRONMENTAL CHANGE ON ABORIGINAL PEOPLE: AN ECONOMIC EXAMINATION OF SUBSISTENCE RESOURCE USE AND VALUE [PDF]

open access: yes
The report describes the research design, data collection and preliminary analysis of an economic assessment of non-timber resource use by Aboriginal People in Northwest Saskatchewan.
Adamowicz, Wiktor L.   +4 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Measured solar irradiance data for resource assessment at four sites in Geba catchment, Tigray, North Ethiopia. [PDF]

open access: yesData Brief, 2022
Bayray M   +8 more
europepmc   +1 more source

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