Results 51 to 60 of about 1,062,445 (387)

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Destruction of the bronchial epithelium in patients with severe asthma according to different patterns of inflammation and cold airway hyperresponsiveness [PDF]

Терапевтический архив, 2019
The aim of the research was to study the state of the bronchial mucosa epi-thelium in relation to the severity of clinical manifestations in severe uncon-trolled asthma depending on the pattern of inflammation and the presence of cold airway ...
A B Pirogov, D A Gassan, S S Zinov’ev, A G Prikhodko, V P Kolosov, J M Perelman   +5 more
doaj   +1 more source

High- and low-pressure pneumotachometers measure respiration rates accurately in adverse environments [PDF]

, 1968
Respiration-rate transducers in the form of pneumotachometers measure respiration rates of pilots operating high performance research aircraft. In each low pressure or high pressure oxygen system a sensor is placed in series with the pilots oxygen supply
Fagot, R. J., Mc Donald, R. T., Roman, J. A.   +2 more
core   +1 more source

Bomb-¹⁴C analysis of ecosystem respiration reveals that peatland vegetation facilitates release of old carbon [PDF]

, 2009
The largest terrestrial-to-atmosphere carbon flux is respired CO₂. However, the partitioning of soil and plant sources, understanding of contributory mechanisms, and their response to climate change are uncertain.
A.E. Fallick, A.P. Rowland, Amundson, Billett, Bol, Bol, Bond-Lamberty, Boutton, Briones, Chanton, Chanton, Chanton, Charman, Clymo, Clymo, Clymo, Colmer, Coplen, Craig, Duranceau, Duranceau, Eddy, Ehleringer, Evans, Fontaine, Forrest, Freeman, Fu, Garnett, Gaudinski, Ghashghaie, Ghashghaie, Gorham, Grogan, Hahn, Hardie, Hardie, Harkness, Harrison, Heal, Högberg, Joabsson, Jobbagy, Jungner, Klumpp, Koarashi, Koncalová, Kuzyakov, Lalonde, Levin, M.H. Garnett, Macdonald, Marinier, N.J. Ostle, Ostle, Ostle, Piao, Piao, Price, Proctor, Raskin, Raskin, Reimer, Rinnan, S.M.L. Hardie, Sapronov, Schimel, Schutz, Schuur, Scott, Shannon, Silvola, Silvola, Slota, Strom, Stuiver, Subke, Taylor, Tcherkez, Tipping, Tolonen, Trumbore, Turetsky, Verville, Waldron, Ward, Ward, Watson, Wookey, Xu, Yakir   +90 more
core   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Long non-coding RNA LINC00485 acts as a microRNA-195 sponge to regulate the chemotherapy sensitivity of lung adenocarcinoma cells to cisplatin by regulating CHEK1

Cancer Cell International, 2019
Background Long non-coding RNAs (lncRNAs) are a family of non-protein-coding RNAs, which have the ability to influence the chemo-resistance of lung adenocarcinoma (LAC).
Wei Zuo, Wei Zhang, Fei Xu, Jing Zhou, Wei Bai   +4 more
doaj   +1 more source

Physiology of purple sulfur bacteria forming macroscopic aggregates in Great Sippewissett Salt Marsh, Massachusetts [PDF]

, 1993
Purple bacterial aggregates found in tidal pools of Great Sippewissett Salt Marsh (Falmouth, Cape Cod, MA) were investigated in order to elucidate the ecological significance of cell aggregation. Purple sulfur bacteria were the dominant microorganisms in
Angelica P. Seitz, Edgar, Gemerden, Gemerden, Gibson, Jörg Overmann, Jørgensen, Kaiser, Nicholson, Oelze, Overmann, Overmann, Overmann, Pfennig, Pierson, Pierson, Revbech, Revsbech, Revsbech, Rosenberg, Steenbergen, Tommy H. Nielsen, Visscher, Wit   +23 more
core   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Decomposition of coarse woody debris in a long-term litter manipulation experiment: A focus on nutrient availability [PDF]

, 2018
The majority of above-ground carbon in tropical forests is stored in wood, which is returned to the atmosphere during decomposition of coarse woody debris.
Gora, Evan M., Sayer, Emma J., Tanner, Edmund V. J., Turner, Benjamin L.   +3 more
core   +3 more sources