Results 61 to 70 of about 395,235 (313)

Nomogram for Predicting Efficacy and Prognosis After Chemotherapy for Advanced NSCLC

open access: yesThe Clinical Respiratory Journal
Purpose One major issue is the therapeutic effect following chemotherapy for non–small cell lung cancer (NSCLC). Although numerous risk factors have been identified and novel therapies have been developed, improving patient overall survival (OS) remains ...
Jiaying Gao   +6 more
doaj   +1 more source

Interaction of tumor necrosis factor-alpha and interferon-gamma with bronchial phagocytic cells in non-allergic bronchial asthma patients

open access: yesСибирский научный медицинский журнал
The contribution of immunoregulatory cytokines to the formation of cold airway hyperresponsiveness in asthma patients is important for understanding approaches to therapy. Aim of the study was to investigate the interaction of tumor necrosis factor-alpha
A. B. Pirogov   +3 more
doaj   +1 more source

NMR screening of low molecular weight inhibitors targeting the papain‐like protease (PLPro) of SARS‐CoV‐2

open access: yesFEBS Open Bio, EarlyView.
Papain‐like protease from SARS‐CoV‐2 plays an important role in the cleavage of the viral polyproteins and in the suppression of the host's immune response. Here, we present the results of an NMR screening study. We identified 86 binding compounds, of which five candidates were chosen for in‐depth analysis.
Dennis J. Pyper   +5 more
wiley   +1 more source

Risk analysis of the Unity 1.5T MR‐Linac adapt‐to‐shape workflow

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background and Purpose The adapt‐to‐shape (ATS) workflow on the Unity MR‐Linac (Elekta AB, Stockholm, Sweden) allows for full replanning including recontouring and reoptimization5. Additional complexity to this workflow is added when the adaptation involves the use of MIM Maestro (MIM Software, Cleveland, OH) software in conjunction with ...
Jiayi Liang   +13 more
wiley   +1 more source

Log file‐based quality assurance method for respiratory gating system

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background As medical linear accelerator technology advances, enabling higher dose rate deliveries, hypofractionation regimens has increased. This necessitates respiratory gating systems that synchronize radiation delivery with tumor position, requiring simple rigorous quality assurance (QA) to ensure treatment accuracy and patient safety ...
Wonjoong Cheon   +7 more
wiley   +1 more source

The edge visualization metric: Quantifying the improvement of lung SBRT target definition with 4D CBCT

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Four‐dimensional cone‐beam CT (4D CBCT) incorporates oversampling of 3D data to reconstruct multi‐phase CBCT data sets representing distinct phases of the breathing cycle based on a diaphragmatic correlate of respiratory motion. Motion artifacts and blurring can be reduced relative to three‐dimensional cone‐beam (3D CBCT), allowing ...
Colton Baley   +4 more
wiley   +1 more source

Research on the treatment of Pseudomonas aeruginosa pneumonia in children by macrolide antibiotics

open access: yesOpen Medicine, 2015
To observe a therapeutic effect of macrolide antibiotics in children with Pseudomonas aeruginosa pneumonia. Fifty-four cases of children with Pseudomonas aeruginosa pneumonia were randomly divided into an observation group (n=30) and a control group (n ...
Huang Xu-qiang   +6 more
doaj   +1 more source

Enhanced analysis of gating latency in 0.35T MR‐linac through innovative time synchronization of a motion phantom and plastic scintillation detector

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study aims to evaluate how different gantry angles, breathing rates (BPM), cine image speeds, and tracking algorithms affect beam on/off latency and the subsequent impact on target dose for a 0.35T MR‐Linac with a 6 MV FFF beam.
Mateb Al Khalifa   +4 more
wiley   +1 more source

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