Respiratory rate responses to both hypercapnia and acidaemia are modified by age in patients with acidosis [PDF]
ObjectiveTo explore the associations between arterial pO2, pCO2 and pH and how these are modified by age.MethodsAn analysis of 2598 patients admitted with a diagnosis of Covid-19 infection to a large UK teaching hospital.ResultsThere were inverse ...
Cruickshank, Simon +23 more
core +1 more source
The author of the presented review article introduces the reader to the basics of such an important clinical problem as acidosis. Respiratory (respiratory) and metabolic acidosis are isolated, which, in turn, is divided into metabolic, exogenous and ...
N. V. Leontyeva
doaj +1 more source
Oxygen therapy in respiratory disorders [PDF]
PhDOxygen therapy remains a cornerstone of medical practice and is generally regarded as being safe. However, there is a lack of clinical evidence to support the routine use of oxygen therapy, and in certain conditions, injudicious oxygen may cause harm.
Wijesinghe, Meme
core +4 more sources
Mixed acid-base disorders, hydroelectrolyte imbalance and lactate production in hypercapnic respiratory failure: the role of noninvasive ventilation. [PDF]
BACKGROUND: Hypercapnic Chronic Obstructive Pulmonary Disease (COPD) exacerbation in patients with comorbidities and multidrug therapy is complicated by mixed acid-base, hydro-electrolyte and lactate disorders.
Claudio Terzano +6 more
doaj +1 more source
CLINICAL. HAEMATOLOGICAL AND ACID-BASE CHANGES ACCOMPANYING SOME RESPIRATORY AND ALIMENTARY MANIFISTATIONS AMONG FATTENING BUFFALOE CALVES [PDF]
The clinical, haematological and some biochemical studies were con ducted on seventy-four buffaloe calves during the prevalence of outbreaks accampanied with respiratory and alimentary manifistations.
A. EL-SEBAIE +3 more
doaj +1 more source
Triggering of erythropoietin production by hypoxia is inhibited by respiratory and metabolic acidosis [PDF]
Erythropoietin (EPO) production in response to hypoxic hypoxia is known to be attenuated by simultaneous hypercapnia. This study aimed to investigate whether this inhibitory effect of hypercapnia is 1) a direct effect of carbon dioxide or mediated by ...
Eckardt, K. U. +5 more
core +1 more source
Resuscitation from a pH of 6.5: A Case Report and Review of Pathophysiology and Management of Extreme Acidosis from Hypovolemic Shock after Trauma [PDF]
Extreme acidosis is a life-threatening physiological state that causes disturbances in the cardiovascular, pulmonary, immune, and hematological systems.
Alexander Balmaceda +3 more
doaj +1 more source
Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis [PDF]
Introduction: Acute metabolic acidosis of non-renal origin is usually a result of either lactic or ketoacidosis, both of which are associated with a high anion gap.
Treacher, David F +17 more
core +1 more source
Reversible mitochondrial respiratory chain impairment during symptomatic hyperlactatemia associated with antiretroviral therapy [PDF]
Direct evidence confirming the hypothesis that a dysfunction of the mitochondrial respiratory chain (MRC) underlies the pathogenesis of hyperlactatemia associated with highly active antiretroviral therapy (HAART) is scarce.
Miró Meda, José M. (José María), 1956- +10 more
core +1 more source
Randomized preclinical study of machine perfusion in vascularized composite allografts
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin +7 more
wiley +1 more source

