Results 51 to 60 of about 754,155 (208)

Cerebrovascular regulation during heat stress

Experimental Physiology, EarlyView.
Abstract Given that the brain is a highly metabolic organ and is enclosed by the skull, effective regulation of cerebral blood flow (CBF), not only for oxygen and nutrients supply but also as a means of convective heat exchange, is critical for preventing excessive elevations in brain temperature.
Kanoko Ito, Manabu Shibasaki
wiley   +1 more source

Impaired Renal Base Excretion in Secretin Receptor Knock-Out Mice During Prolonged Base-Loading. [PDF]

Acta Physiol (Oxf)
ABSTRACT Aim Secretin was recently found to play a pivotal role in the renal adaptation to acute base excess. Here, secretin increases pendrin‐dependent HCO3− secretion from the beta‐intercalated cells in the cortical collecting ducts. Whether secretin and its receptor play a role during prolonged base‐loading remains unknown.
Jensen T, Andersen JF, Trans LW, Modvig IM, Vitzthum H, Holst JJ, Hartman B, Svendsen SL, Sørensen MV, Leipziger J, Berg P.   +10 more
europepmc   +2 more sources

Brain strain: Blood flow and metabolism in environmental extremes

Experimental Physiology, EarlyView.
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak, Damian M. Bailey, Travis D. Gibbons, Philip N. Ainslie   +3 more
wiley   +1 more source

Hypercapnea and Acidemia despite Hyperventilation following Endotracheal Intubation in a Case of Unknown Severe Salicylate Poisoning

Case Reports in Critical Care, 2017
Salicylates are common substances for deliberate self-harm. Acute salicylate toxicity is classically associated with an initial respiratory alkalosis, followed by an anion gap metabolic acidosis.
Shannon M. Fernando, Valérie Charbonneau, Hans Rosenberg   +2 more
doaj   +1 more source

Beta-receptors in resistance to phosphaturic effect of PTH in respiratory alkalosis

, 1988
Respiratory alkalosis results in a resistance to the phosphaturic effect of parathyroid hormone (PTH) and dibutyryl adenosine 3',5'-cyclic monophosphate (cAMP).
S. Angielski, A. Rybczynska, A. Hoppe, F. G. Knox   +3 more
core   +1 more source

Early acclimatization to high altitude: Acid–base and fluid balance dynamics during the first 2 days at 3100 m

Experimental Physiology
Immediate responses to hypoxia at high altitude are hyperventilation and successive respiratory alkalosis. Alkalosis, in turn, can affect cerebrospinal fluid pH and ventilatory control. The kidneys compensate metabolically for respiratory alkalosis.
Elisabeth Skalla, Benedikt Treml, Sasa Rajsic, Michael Schreinlechner, Zoran Bukumirić, Klaus Berek, Alexander Egger, Johann Knotzer, Martin Burtscher, Axel Kleinsasser   +9 more
doaj   +1 more source

Fetal Metabolic Alkalosis Resulting from Maternal Vomiting

American Journal of Perinatology Reports
We describe a pregnant patient with severe compulsive water ingestion and vomiting that lead to metabolic alkalosis and preterm delivery. A 21-year-old patient was hospitalized multiple times throughout pregnancy for symptoms initially thought to be ...
William M. Curtin, Emily A. O'Brien, Rachel M. Mauro, Elizabeth A. Lucarelli-Baldwin, Serdar H. Ural, Christina T. DeAngelis   +5 more
doaj   +1 more source

Role of hormonal factors in plasma K alterations in acute respiratory and metabolic alkalosis in dogs

, 1990
Studies were performed on previously nephrectomized dogs to examine roles of hormonal factors in plasma potassium alterations in acute alkalosis.
K. Ohishi, N. Honda, A. Hishida, H. Suzuki, M. Kimura   +4 more
core   +1 more source

The role of acid‐base balance in cerebrovascular and ventilatory responses to CO2 during 10 h normobaric hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend During 10 h exposures to normobaric hypoxia exposure there was a selective leftward shift in ventilatory response to hyperoxic hypercapnic rebreathing, but not the cerebrovascular response. The key findings are that the resetting of the central chemoreflex to lower PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$ during early hypoxic ...
Holly Barclay, Saptarshi Mukerji, Bengt Kayser, Jui‐Lin Fan   +3 more
wiley   +1 more source

Assessment of Blood pH and pCO2 as Predictors of Febrile Seizures in Paediatric Patients: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Febrile seizures commonly occur in the age group of six months to five years. Hypocarbia and alkalosis are known to enhance neuronal excitability and promote epileptiform activity.
Suhit Banerjee, Tapan Kumar Biswas, Gobinda Mondal, Banasree Roy, Anish Chatterjee   +4 more
doaj   +1 more source