Results 51 to 60 of about 496,340 (170)

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Respiratory chains of archaea and extremophiles

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1996
Extremophilic organisms are adapted to harsh environmental conditions like high temperature, extremely acidic or alkaline pH, high salt, or a combination of those. With a few exceptions extremophilic bacteria are colonizing only moderately hot biotopes, whereas hyperthermophiles are found specifically among archaea (formerly 'archaebacteria') which can
Schäfer, Günter, Purschke, Werner G., Gleissner, Michael, Schmidt, Christian L.   +3 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The respiratory chain of alkaliphilic bacteria

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1995
Alkaliphilic bacteria that grow at extremely high pH are confronted by particular bioenergetic problems in carrying out oxidative phosphorylation. This project focused on the properties and adaptations of the respiratory chain. The respiratory chain as a whole, the redox poises of its components and several individual complexes of the respiratory chain
Hicks, David B., Krulwich, Terry A.
openaire   +2 more sources

Sugar-oxidizing Respiratory Chain ofGluconobacter suboxydans. Evidence for a Branched Respiratory Chain and Characterization of Respiratory Chain-Linked Cytochromes [PDF]

Agricultural and Biological Chemistry, 1987
Gluconobacter suboxydans has a highly active respiratory chain which oxidizes several sugars and sugar alcohols. The results of this study indicate that the sugar-oxidizing respiratory chain consists of ubiquinone, several cytochromes c and a cytochrome o. The respiratory chain was shown to contain at least five cytochromes, including two cytochromes c
AMEYAMA, Minoru, MATSUSHITA, Kazunobu, SHINAGAWA, Emiko, ADACHI, Osao   +3 more
openaire   +2 more sources

The two alternative NADH:quinone oxidoreductases from Staphylococcus aureus: two players with different molecular and cellular roles

Microbiology Spectrum
Staphylococcus aureus is an opportunistic pathogen that has emerged as a major public health threat due to the increased incidence of its drug resistance. S.
Filipa V. Sena, Filipe M. Sousa, Ana R. Pereira, Teresa Catarino, Eurico J. Cabrita, Mariana G. Pinho, Francisco R. Pinto, Manuela M. Pereira   +7 more
doaj   +1 more source

Effects of different frequencies of physical training on electron transport chain and oxidative damage in healthy mice

Motriz: Revista de Educacao Fisica, 2018
Aims: The present study investigated the effect of different frequencies (three and five times a week) on electron transport chain and oxidative stress after 8 weeks of run training.
Luciano A. Silva, Camila B. Tromm, Ramiro Doyenart, Anand Thirupathi, Paulo Cesar Loock Silveira, Ricardo Aurinho Pinho   +5 more
doaj   +1 more source

Cytochrome c Oxidase Subunit 4 Isoform Exchange Results in Modulation of Oxygen Affinity

Cells, 2020
Cytochrome c oxidase (COX) is regulated through tissue-, development- or environment-controlled expression of subunit isoforms. The COX4 subunit is thought to optimize respiratory chain function according to oxygen-controlled expression of its isoforms ...
David Pajuelo Reguera, Kristýna Čunátová, Marek Vrbacký, Alena Pecinová, Josef Houštěk, Tomáš Mráček, Petr Pecina   +6 more
doaj   +1 more source

Essential role of cytochrome bc1 in Pseudomonas aeruginosa cell physiology and virulence

Frontiers in Cellular and Infection Microbiology
Pseudomonas aeruginosa is a multidrug-resistant Gram-negative nosocomial pathogen posing a major healthcare burden due to its intrinsic antibiotic resistance and environmental adaptability, which continue to significantly constrain therapeutic options ...
Jennifer M. Sorescu, Martín A. González-Montalvo, Nancy Patel, Gabriella Baltes, Shriya R. Avula, Karina Tuz, Oscar X. Juárez   +6 more
doaj   +1 more source

Improved method for isolation of coupled mitochondria of Araucaria angustifolia (Bert.) O. Kuntze

Brazilian Archives of Biology and Technology, 2004
A method for the isolation of coupled mitochondria from the callus of Araucaria angustifolia is described for the first time. Mitochondria were isolated from embryogenic callus of A. angustifolia. They were metabolically active, able to sustain oxidative
André Bellin Mariano, Leonardo Kovalhuk, Caroline Valente, Juliana Maurer-Menestrina, Adaucto Bellarmino Pereira-Netto, Miguel Pedro Guerra, Eva Gunilla Skare Carnieri   +6 more
doaj   +1 more source