Results 71 to 80 of about 497,443 (308)

Improved method for isolation of coupled mitochondria of Araucaria angustifolia (Bert.) O. Kuntze

Brazilian Archives of Biology and Technology, 2004
A method for the isolation of coupled mitochondria from the callus of Araucaria angustifolia is described for the first time. Mitochondria were isolated from embryogenic callus of A. angustifolia. They were metabolically active, able to sustain oxidative
André Bellin Mariano, Leonardo Kovalhuk, Caroline Valente, Juliana Maurer-Menestrina, Adaucto Bellarmino Pereira-Netto, Miguel Pedro Guerra, Eva Gunilla Skare Carnieri   +6 more
doaj   +1 more source

Inhibition of Respiration of Candida albicans by Small Molecules Increases Phagocytosis Efficacy by Macrophages

mSphere, 2020
Candida albicans adapts to various conditions in different body niches by regulating gene expression, protein synthesis, and metabolic pathways. These adaptive reactions not only allow survival but also influence the interaction with host cells, which is
Shuna Cui, Minghui Li, Rabeay Y. A. Hassan, Anna Heintz-Buschart, Junsong Wang, Ursula Bilitewski   +5 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

The point prevalence of respiratory syncytial virus in hospital and community-based studies in children from Northern Australia: studies in a ‘high-risk’ population

, 2019
Background: Candidate respiratory syncytial virus (RSV) vaccine trials in pregnant women and infants are underway and a greater understanding of RSV epidemiology is now needed, especially in paediatric populations with high rates of acute and chronic ...
Amanda Leach, Lesley Versteegh, McCallum, Gabrielle, Oguoma, Victor, Keith Grimwood, Versteegh, Lesley, Gabrielle McCallum, Heidi Smith-Vaughan, Chang, Anne, Smith-Vaughan, Heidi, Grimwood, Keith, Anne Chang, Victor Oguoma, Leach, Amanda   +13 more
core   +1 more source

α-Mangostin Competing the Menaquinone-Binding Sites of NDH-2 to Block the Electron Transfer at the Quinone Pool of Staphylococcus aureus

Antibiotics
Background/Objectives: α-Mangostin, a natural product from Garcinia mangostana L, presents very strong antibacterial activity in plant flavonoids against Staphylococcus aureus.
Meifang Zhang, Jianing Hu, Yu Wang, Liaolongyan Luo, Ganjun Yuan   +4 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Mitochondrial HER2 stimulates respiratory chain function and drives tumorigenicity of breast cancer cells

, 2019
Amplification of HER2/ERBB2, a breast cancer oncogene, leads to resistance to therapy and poor prognosis in breast cancer patients. HER2, a member of the EGFR protein family, normally localizes to the plasma membrane.
Novotna, Eliska, Rohlena, Jakub, Rohlenova, Katerina, Novais, Silvia Magalhaes, Neuzil, Jiri   +4 more
core   +1 more source

Mitochondrial DNA mutations and respiratory chain dysfunction in idiopathic and connective tissue disease-related lung fibrosis. [PDF]

, 2019
Reactive oxygen species (ROS) are implicated in the aetiology of interstitial lung disease (ILD). We investigated the role of large-scale somatically acquired mutations in mitochondrial DNA (mtDNA) and consecutive respiratory chain dysfunction as a ...
Nicholson, Andrew G., Bhayani, Harshil, Tamm, Michael, Jaeger, Veronika K, Wells, Athol, Walker, Ulrich A., Nicholson, Andrew G, Gazdhar, Amiq, Geiser, Thomas, Venhoff, Nils, Jaeger, Veronika K., Walker, Ulrich A, Lebrecht, Dirk   +12 more
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

The Respiratory Chain of Alkaliphilic Bacteria [PDF]

, 2008
Alkaliphilic bacteria that grow at extremely high pH are confronted by particular bioenergetic problems in carrying out oxidative phosphorylation. This project focused on the properties and adaptations of the respiratory chain. The respiratory chain as a
Krulwich, Terry Ann
core   +1 more source