Differences in mitochondrial NADH dehydrogenase activities in trypanosomatids. [PDF]
Parasitology, 2021 AbstractComplex I (NADH dehydrogenase) is the first enzyme in the respiratory chain. It catalyses the electron transfer from NADH to ubiquinone that is associated with proton pumping out of the matrix. In this study, we characterized NADH dehydrogenase activity in seven monoxenous trypanosomatid species: Blechomonas ayalai, Herpetomonas tarakana ...
Čermáková P +5 more
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TCA cycle tailoring facilitates optimal growth of proton-pumping NADH dehydrogenase-dependent Escherichia coli [PDF]
Microbiology Spectrum, 2023 The bacterial lifestyle is plastic, requiring transcriptional, translational, and metabolic tailoring for survival. These dynamic cellular processes are energy intensive; therefore, flexible energetics is requisite for adaptive plasticity.
Nikita Goel +7 more
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Relevance of NADH Dehydrogenase and Alternative Two-Enzyme Systems for Growth of Corynebacterium glutamicum With Glucose, Lactate, and Acetate [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 The oxidation of NADH with the concomitant reduction of a quinone is a crucial step in the metabolism of respiring cells. In this study, we analyzed the relevance of three different NADH oxidation systems in the actinobacterial model organism ...
Tomoya Maeda +2 more
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Molecular Cell, 2020 The proteolytic turnover of mitochondrial proteins is poorly understood. Here, we used a combination of dynamic isotope labeling and mass spectrometry to gain a global overview of mitochondrial protein turnover in yeast cells.
Sreedivya Saladi +2 more
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NADH Dehydrogenase Deficiency [PDF]
Definitions, 2020 A rare metabolic disorder characterized by the deficiency of mitochondrial NADH dehydrogenase component of complex I. Signs and symptoms include cardiomyopathy, encephalopathy, enlarged head, and progressive leukodystrophy.
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Novel mitochondrial complex I-inhibiting peptides restrain NADH dehydrogenase activity. [PDF]
Sci Rep, 2019 The emergence of drug-resistant fungal pathogens is becoming increasingly serious due to overuse of antifungals. Antimicrobial peptides have potent activity against a broad spectrum of pathogens, including fungi, and are considered a potential new class ...
Xue YP, Kao MC, Lan CY.
europepmc +2 more sources
Mitochondrial type II NADH dehydrogenase of Plasmodium falciparum (PfNDH2) is dispensable in the asexual blood stages. [PDF]
PLoS One, 2019 The battle against malaria has been substantially impeded by the recurrence of drug resistance in Plasmodium falciparum, the deadliest human malaria parasite.
Ke H +8 more
europepmc +2 more sources
NADH dehydrogenase of Corynebacterium glutamicum. Purification of an NADH dehydrogenase II homolog able to oxidize NADPH [PDF]
FEMS Microbiology Letters, 2001 NADPH oxidase activity, in addition to NADH oxidase activity, has been shown to be present in the respiratory chain of Corynebacterium glutamicum. In this study, we tried to purify NADPH oxidase and NADH dehydrogenase activities from the membranes of C. glutamicum.
Kazunobu Matsushita +2 more
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NADH dehydrogenase (ubiquinone)
Definitions, 1994 and a role in the of the mitochondrial electron transport chain.
D. Schomburg, M. Salzmann, D. Stephan
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mBio, 2023 Type 2 NADH dehydrogenase (Ndh-2) is an oxidative phosphorylation enzyme discussed as a promising drug target in different pathogens, including Plasmodium falciparum and Mycobacterium tuberculosis (Mtb).
Yuanyuan Xu +3 more
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