Effects of cipepofol on breathing patterns, respiratory drive, and inspiratory effort in mechanically ventilated patients [PDF]
Frontiers in MedicineBackgroundCipepofol is a highly selective gamma-aminobutyric acid A receptor potentiator. As a new sedative drug, detailed studies on its respiratory effects are further needed.
Rui Su +7 more
doaj +4 more sources
Clinical risk factors for increased respiratory drive in intubated hypoxemic patients [PDF]
Critical Care, 2023 Background There is very limited evidence identifying factors that increase respiratory drive in hypoxemic intubated patients. Most physiological determinants of respiratory drive cannot be directly assessed at the bedside (e.g., neural inputs from chemo-
Elena Spinelli +13 more
doaj +2 more sources
Surface electromyography to quantify neuro-respiratory drive and neuro-mechanical coupling in mechanically ventilated children [PDF]
Respiratory Research, 2023 Background The patient’s neuro-respiratory drive, measured as electrical activity of the diaphragm (EAdi), quantifies the mechanical load on the respiratory muscles.
Alette A. Koopman +4 more
doaj +2 more sources
Effects of three spontaneous ventilation modes on respiratory drive and muscle effort in COVID-19 pneumonia patients [PDF]
BMC Pulmonary Medicine, 2023 Background High drive and high effort during spontaneous breathing can generate patient self-inflicted lung injury (P-SILI) due to uncontrolled high transpulmonary and transvascular pressures, with deterioration of respiratory failure.
José Manuel Serrano Simón +9 more
doaj +2 more sources
Breath-by-breath P0.1 measured on quasi-occlusion via Hamilton C6 may result in underestimation of respiratory drive and inspiratory effort [PDF]
Critical Care, 2022 We aimed to identify the threshold for P0.1 in a breath-by-breath manner measured by the Hamilton C6 on quasi-occlusion for high respiratory drive and inspiratory effort.
Ryo Takane +6 more
doaj +2 more sources
Respiratory drive: a journey from health to disease [PDF]
Journal of Intensive CareRespiratory drive is defined as the intensity of respiratory centers output during the breath and is primarily affected by cortical and chemical feedback mechanisms.
Dimitrios Georgopoulos +3 more
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The deep and slow breathing characterizing rest favors brain respiratory-drive [PDF]
Scientific Reports, 2021 A respiration-locked activity in the olfactory brain, mainly originating in the mechano-sensitivity of olfactory sensory neurons to air pressure, propagates from the olfactory bulb to the rest of the brain.
Baptiste Girin +6 more
doaj +2 more sources
Neural respiratory drive during maximal voluntary ventilation in individuals with hypertension: A case-control study. [PDF]
PLoS ONENeural respiratory drive (NRD) is measured using a non-invasive recording of respiratory electromyographic signal. The parasternal intercostal muscle can assess the imbalance between the load and capacity of respiratory muscles and presents a similar ...
Andressa V S O N Cavalcante +7 more
doaj +2 more sources
Omics approach to chest electrical impedance tomography reveals physiological cluster of ARDS characterised by increased respiratory drive and effort [PDF]
Annals of Intensive CareBackground: Non-invasive assessment of respiratory drive and effort in spontaneously breathing ARDS patients is challenging, yet clinically relevant. We explored whether hierarchical clustering applied to electrical impedance tomography (EIT– a radiation-
Tommaso Mauri +7 more
doaj +2 more sources
Frontiers in Neurology, 2019 Objective: The goal of this study is to evaluate pulmonary function and respiratory center drive in patients with early-stage idiopathic Parkinson's disease (IPD) to facilitate early diagnosis of Parkinson's Disease (PD).Methods: 43 IPD patients (Hoehn ...
Wei Zhang +14 more
doaj +3 more sources