Evaluation of a translational swine model of respiratory hypersensitivity induced by exposure to Phleum pratense pollen allergens [PDF]
Frontiers in AllergyIntroductionAsthma is a disease characterized by chronic inflammation of the airway mucosa that causes tissue remodeling and a reversible decrease in airflow.
Jessica Ledesma-Aparicio +7 more
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Long-term nitric oxide exposure induces cough hypersensitivity via non-inflammatory activation of the HIF1α–TRPV1 pathway [PDF]
Frontiers in PharmacologyBackgroundChronic cough hypersensitivity is common across respiratory diseases and often occurs without airway inflammation, yet effective treatments remain limited.
Jingxin Zhao +9 more
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Respiratory hypersensitivity reaction related to ingestion of raspberry
Journal of Cutaneous Immunology and Allergy, 2023 A 27‐year‐old woman developed dyspnea and wheezing within 10 min after eating a piece of raspberry walnut cake, and was successfully treated with intravenous corticosteroid and intramuscular injection of adrenaline.
Yuki Akamatsu +6 more
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Frontiers in Allergy, 2023 BackgroundChronic rhinosinusitis with nasal polyps (CRSwNP) and asthma frequently co-exist and share pathologic features. Taking a “global” treatment approach benefits diagnosis and treatment of both, but care is often siloed by specialty: joined-up ...
Vibeke Backer +26 more
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Symptoms, physical findings and bronchial hypersensitivity in patients with bronchial asthma and normal spirometry [PDF]
Vojnosanitetski Pregled, 2009 Background/Aim. The diagnosis of bronchial asthma, a chronic inflammatory disease of the respiratory tract, is made on the basis of anamnesis, pathologic auscultatory findings of the lungs, lung function disturbances, skin tests, as well as the basic ...
Aćimović Slobodan +6 more
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The relation between nonspecific hyperreactivity of the airways and atopic constitution in asthmatics [PDF]
Vojnosanitetski Pregled, 2016 Background/Aim. Hyperreactivity of the airways caused by inflammation in asthmatics is the most important pathophysiological change. It represents a suitable ground that in the presence of risk factors and the drivers of asthma, asthmatic attack occurs ...
Novković Dobrivoje +3 more
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Assessing the Potential to Induce Respiratory Hypersensitivity [PDF]
Toxicological Sciences, 2005 Acute and repeat dose inhalation studies have been an important part of the safety assessment of drugs, chemicals, and other products throughout the world for many years. It is known that damage to the respiratory tract can be triggered either by nonspecific irritation or by specific immune-mediated pathogenesis, and it is acknowledged that traditional
Holsapple, Michael P. +7 more
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Allergic cross-reactivity – anew challenge for allergists?
Pediatria i Medycyna Rodzinna, 2015 Allergic cross-reactivity is an important epidemiological issue in all age groups. It is caused by a non-specific binding of both primary allergen as well as allergens causing secondary cross-reactivity by the same IgE antibodies.
Krzysztof Łukasz Piwowarek +3 more
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Pharmacogenomics of Hypersensitivity to Non-steroidal Anti-inflammatory Drugs
Frontiers in Genetics, 2021 Non-steroidal anti-inflammatory drugs (NSAIDs) are extensively prescribed in daily clinical practice. NSAIDs are the main cause of drug hypersensitivity reactions all over the world.
Hoang Kim Tu Trinh +3 more
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Cladosporium herbarum Hot-Tub Lung Hypersensitivity Pneumonitis in a Greenhouse Worker
European Journal of Case Reports in Internal Medicine, 2020 Hypersensitivity pneumonitis is understood to be a delayed allergic reaction to the repeated exposure of a usually innocent inhaled agent, causing inflammatory damage to the pulmonary parenchyma, alveoli and terminal bronchioles.
João Pedro Abreu +5 more
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