Artificial Intelligence-Driven Prognosis of Respiratory Mechanics: Forecasting Tissue Hysteresivity Using Long Short-Term Memory and Continuous Sensor Data. [PDF]
Sensors (Basel)Othman GB +9 more
europepmc +3 more sources
Surface mechanomyography and electromyography provide non-invasive indices of inspiratory muscle force and activation in healthy subjects [PDF]
, 2018 The current gold standard assessment of human inspiratory muscle function involves using invasive measures of transdiaphragmatic pressure (Pdi) or crural diaphragm electromyography (oesEMGdi).
Jané Campos, Raimon +6 more
core +2 more sources
Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation [PDF]
, 2011 Deficiency of vitamin D is associated with accelerated decline in lung function. Vitamin D is a ligand for nuclear hormone vitamin D receptor (VDR), and upon binding it modulates various cellular functions.
Hwang, Jae-woong +4 more
core +1 more source
Some frequency domain considerations upon human respiratory mechanics [PDF]
, 2004 The aim of this paper is to present a brief analysis of recent results considering human respiratory mechanics. The final purpose of the investigation is to provide a fast method for identification of airway mechanics, in order to assist the medical ...
De Keyser, Robain +1 more
core +1 more source
Effect of external PEEP in patients under controlled mechanical ventilation with an auto-PEEP of 5 cmH2O or higher. [PDF]
, 2016 In some patients with auto-positive end-expiratory pressure (auto-PEEP), application of PEEP lower than auto-PEEP maintains a constant total PEEP, therefore reducing the inspiratory threshold load without detrimental cardiovascular or respiratory effects.
Amodeo, Guido +16 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2017 Context: Calcium channel blockers may theoretically exhibit relaxing effects not only on vascular smooth muscle but also on airway smooth muscle. Objective: To investigate possible effects of nifedipine on respiratory mechanics in the rat.
Alessandro Rubini +3 more
doaj +1 more source
Expiratory model-based method to monitor ARDS disease state [PDF]
, 2013 INTRODUCTION: Model-based methods can be used to characterise patient-specific condition and response to mechanical ventilation (MV) during treatment for acute respiratory distress syndrome (ARDS).
Chase, JG +7 more
core +2 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Prognostic value of pulmonary dead space in patients with the acute respiratory distress syndrome. [PDF]
, 2011 A study published in the previous issue of Critical Care demonstrates that measurement of the pulmonary dead-space fraction is superior to hypoxemia as an indicator of a favorable physiologic response to prone positioning in patients with severe acute ...
Kallet, Richard H, Matthay, Michael A
core +1 more source