Results 21 to 30 of about 208,910 (323)

Mucosal Immune Responses to Respiratory Syncytial Virus

Cells, 2022
Despite over half a century of research, respiratory syncytial virus (RSV)-induced bronchiolitis remains a major cause of hospitalisation in infancy, while vaccines and specific therapies still await development.
Megan V. C. Barnes, Peter J. M. Openshaw, Ryan S. Thwaites   +2 more
doaj   +1 more source

Effects of Cigarette Smoke on the Nasal Respiratory and Olfactory Mucosa in Allergic Rhinitis Mice

Frontiers in Neuroscience, 2020
ObjectiveCigarette smoke (CS) exposure reportedly enhances allergic airway inflammation. However, some studies have shown an association between current cigarette smoke exposure and a low risk for allergic rhinitis.
Rumi Ueha, Satoshi Ueha, Kenji Kondo, Hironobu Nishijima, Tatsuya Yamasoba   +4 more
doaj   +1 more source

Inflammatory mediators in nasal secretions of patients with nasal polyposis with and without aspirin sensitivity

Immunity, Inflammation and Disease, 2023
Background The aim of this cross‐sectional study was to compare the levels of inflammatory mediators in nasal secretions in patients with aspirin‐exacerbated respiratory disease (AERD) and in those with nasal polyposis (NP) without aspirin‐sensitivity ...
Aleksandar Perić, Dejan Gaćeša, Gordana Cvetković, Danilo Vojvodić   +3 more
doaj   +1 more source

Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir [PDF]

, 2014
Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza ...
Barclay, Wendy S., Bean, Thomas J., Bruce, Christine, Carroll, Miles W., Dimmock, N. J., Dove, Brian K., Dowall, Stuart, Easton, A. J. (Andrew J.), Hallis, Bassam, Marriott, Anthony C., Newman, Edmund, Pearson, Geoff, Plank, Jenna, Rayner, Emma, Ryan, Kathryn A., Silman, Nigel J., Taylor, Irene, Whittaker, Catherine J.   +17 more
core   +12 more sources

Advancing Immunotherapeutic Vaccine Strategies Against Pulmonary Tuberculosis

Frontiers in Immunology, 2020
Chemotherapeutic intervention remains the primary strategy in treating and controlling tuberculosis (TB). However, a complex interplay between therapeutic and patient-related factors leads to poor treatment adherence.
Sam Afkhami, Sam Afkhami, Sam Afkhami, Anne Drumond Villela, Anne Drumond Villela, Anne Drumond Villela, Michael R. D’Agostino, Michael R. D’Agostino, Michael R. D’Agostino, Mangalakumari Jeyanathan, Mangalakumari Jeyanathan, Mangalakumari Jeyanathan, Amy Gillgrass, Amy Gillgrass, Amy Gillgrass, Zhou Xing, Zhou Xing, Zhou Xing   +17 more
doaj   +1 more source

Nasal Nitric Oxide in the Upper Airway Inflammatory Diseases [PDF]

Journal of Rhinology, 2021
Exhaled nitric oxide (eNO) from the lower respiratory tract is used commonly in diagnosis and treatment monitoring of asthma patients. However, nasal nitric oxide (nNO) has not been widely used in patients with upper airway inflammatory diseases due to ...
Jin Hyeok Jeong
doaj   +1 more source

Development of a physiological model of human middle ear epithelium

Laryngoscope Investigative Otolaryngology, 2021
Introduction Otitis media is an umbrella term for middle ear inflammation; ranging from acute infection to chronic mucosal disease. It is a leading cause of antimicrobial therapy prescriptions and surgery in children.
Michael William Mather, Bernard Verdon, Rachel Anne Botting, Justin Engelbert, Livia Delpiano, Xin Xu, Catherine Hatton, Tracey Davey, Steven Lisgo, Philip Yates, Nicholas Dawe, Colin D. Bingle, Muzlifah Haniffa, Jason Powell, Chris Ward   +14 more
doaj   +1 more source

B Cell Mobilization, Dissemination, Fine Tuning of Local Antigen Specificity and Isotype Selection in Asthma

Frontiers in Immunology, 2021
In order to better understand how the immune system interacts with environmental triggers to produce organ-specific disease, we here address the hypothesis that B and plasma cells are free to migrate through the mucosal surfaces of the upper and lower ...
Line Ohm-Laursen, Line Ohm-Laursen, Hailong Meng, Kenneth B. Hoehn, Nima Nouri, Nima Nouri, Yue Jiang, Chris Clouser, Timothy G. Johnstone, Ron Hause, Balraj S. Sandhar, Balraj S. Sandhar, Nadine E. G. Upton, Nadine E. G. Upton, Elfy B. Chevretton, Raj Lakhani, Chris J. Corrigan, Chris J. Corrigan, Steven H. Kleinstein, Steven H. Kleinstein, Steven H. Kleinstein, Hannah J. Gould, Hannah J. Gould   +22 more
doaj   +1 more source

Haemophilus parainfluenzae infection of respiratory mucosa

Respiratory Medicine, 2003
The pathogenicity of Haemophilus parainfluenzae (Hpi) in the respiratory tract is unclear, in contrast to the accepted pathogenicity of its close relative non-typable H. influenzae. We have investigated the interaction of two Hpi isolates with the mucosa of adenoid and bronchial tissue organ cultures.
MIDDLETON, A.M., DOWLING, R.B., MITCHELL, J.L., WATANABE, S., RUTMAN, A., PRITCHARD, K., TILLOTSON, G., HILL, S.L., WILSON, R.   +8 more
openaire   +2 more sources

Replication characteristics of porcine reproductive and respiratory syndrome virus (PRRSV) European subtype 1 (Lelystad) and subtype 3 (Lena) strains in nasal mucosa and cells of the monocytic lineage: indications for the use of new receptors of PRRSV (Lena) [PDF]

, 2013
Recently, it has been demonstrated that subtype 3 strains of European type porcine reproductive and respiratory syndrome virus (PRRSV) are more virulent/pathogenic than subtype 1 strains. This points to differences in the pathogenesis.
Cao, Jun, Frydas, Ilias, Nauwynck, Hans, Verbeeck, Mieke   +3 more
core   +2 more sources