Results 11 to 20 of about 126,476 (295)

Disruption of IL-17-mediated immunosurveillance in the respiratory mucosa results in invasive Streptococcus pyogenes infection. [PDF]

Front Immunol
Introduction: Streptococcus pyogenes is a Gram-positive pathogen that causes a significant global burden of skin pyoderma and pharyngitis. In some cases, infection can lead to severe invasive streptococcal diseases. Previous studies have shown that IL-17
Mills JL, Lepletier A, Ozberk V, Dooley J, Kaden J, Calcutt A, Huo Y, Hicks A, Zaid A, Good MF, Pandey M.   +10 more
europepmc   +2 more sources

Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection. [PDF]

Science, 2020
INTRODUCTION Even with intimate exposure to a virus, some people fail to become infected. Variable transmission partly depends on the dose and duration of exposure but is also governed by the immune status of the host, such as the presence of specific ...
Habibi MS, Thwaites RS, Chang M, Jozwik A, Paras A, Kirsebom F, Varese A, Owen A, Cuthbertson L, James P, Tunstall T, Nickle D, Hansel TT, Moffatt MF, Johansson C, Chiu C, Openshaw PJM.   +16 more
europepmc   +3 more sources

The Safety of Topical and Intravenous Tranexamic Acid in Endoscopic Sinus Surgery

Sinusitis, 2022
Tranexamic acid (TXA) is an inexpensive and widely used medication indicated for the reduction of bleeding. There are data showing the efficacy of intravenous (IV) and topical TXA in endoscopic sinus surgery (ESS) but the safety of this practice is not ...
Agrani Ratnayake Kumar, Andrew James Wood   +1 more
doaj   +1 more source

Mucosal Immune Responses to Respiratory Syncytial Virus

Cells, 2022
Despite over half a century of research, respiratory syncytial virus (RSV)-induced bronchiolitis remains a major cause of hospitalisation in infancy, while vaccines and specific therapies still await development.
Megan V. C. Barnes, Peter J. M. Openshaw, Ryan S. Thwaites   +2 more
doaj   +1 more source

Development of Acellular Respiratory Mucosal Matrix Using Porcine Tracheal Mucosa [PDF]

, 2021
Background: Respiratory mucosa defects result in airway obstruction and infection, requiring subsequent functional recovery of the respiratory epithelium.
김한수, 정수연, 최은오
core   +1 more source

Development of a physiological model of human middle ear epithelium

Laryngoscope Investigative Otolaryngology, 2021
Introduction Otitis media is an umbrella term for middle ear inflammation; ranging from acute infection to chronic mucosal disease. It is a leading cause of antimicrobial therapy prescriptions and surgery in children.
Michael William Mather, Bernard Verdon, Rachel Anne Botting, Justin Engelbert, Livia Delpiano, Xin Xu, Catherine Hatton, Tracey Davey, Steven Lisgo, Philip Yates, Nicholas Dawe, Colin D. Bingle, Muzlifah Haniffa, Jason Powell, Chris Ward   +14 more
doaj   +1 more source

Supplementation With Spirulina platensis Improves Tracheal Reactivity in Wistar Rats by Modulating Inflammation and Oxidative Stress

Frontiers in Pharmacology, 2022
Spirulina platensis has shown effectiveness in the treatment of allergic rhinitis in rats, but its action in tracheal reactivity or on markers of relaxation and antioxidant profile has not yet been possible to determine.
Aline de F. Brito, Aline de F. Brito, Alexandre S. Silva, Alexandre S. Silva, Alesandra A. de Souza, Alesandra A. de Souza, Paula B. Ferreira, Iara L. L. de Souza, Layanne C. da C. Araujo, Bagnólia A. da Silva, Bagnólia A. da Silva   +10 more
doaj   +1 more source

Inflammatory mediators in nasal secretions of patients with nasal polyposis with and without aspirin sensitivity

Immunity, Inflammation and Disease, 2023
Background The aim of this cross‐sectional study was to compare the levels of inflammatory mediators in nasal secretions in patients with aspirin‐exacerbated respiratory disease (AERD) and in those with nasal polyposis (NP) without aspirin‐sensitivity ...
Aleksandar Perić, Dejan Gaćeša, Gordana Cvetković, Danilo Vojvodić   +3 more
doaj   +1 more source

Effects of Cigarette Smoke on the Nasal Respiratory and Olfactory Mucosa in Allergic Rhinitis Mice

Frontiers in Neuroscience, 2020
ObjectiveCigarette smoke (CS) exposure reportedly enhances allergic airway inflammation. However, some studies have shown an association between current cigarette smoke exposure and a low risk for allergic rhinitis.
Rumi Ueha, Satoshi Ueha, Kenji Kondo, Hironobu Nishijima, Tatsuya Yamasoba   +4 more
doaj   +1 more source

Genotoxicity of nitroso compounds and sodium dichromate in a model combining organ cultures of human nasal epithelia and the comet assay [PDF]

, 2001
Genotoxic effects of xenobiotics are a possible step in tumor initiation in the mucosa of the upper aerodigestive tract. Using the comet assay, detecting genotoxicity in human tissue has been restricted to single incubations in vitro, but in vivo most ...
Bergner, Albrecht, Kastenbauer, Ernst R., Gamarra, Fernando, Kleinsasser, Norbert H., Harréus, Ulrich A., Huber, Rudolf M., Wallner, Barbara C., Juchhoff, Jutta   +7 more
core   +1 more source