Genotoxicity of nitroso compounds and sodium dichromate in a model combining organ cultures of human nasal epithelia and the comet assay [PDF]
Genotoxic effects of xenobiotics are a possible step in tumor initiation in the mucosa of the upper aerodigestive tract. Using the comet assay, detecting genotoxicity in human tissue has been restricted to single incubations in vitro, but in vivo most ...
Bergner, Albrecht +7 more
core +1 more source
In order to better understand how the immune system interacts with environmental triggers to produce organ-specific disease, we here address the hypothesis that B and plasma cells are free to migrate through the mucosal surfaces of the upper and lower ...
Line Ohm-Laursen +22 more
doaj +1 more source
Paraneoplastic Pemphigus Involving the Respiratory and Gastrointestinal Mucosae [PDF]
Paraneoplastic pemphigus (PNP), an autoimmune mucocutaneous disorder involving the oral and bronchial mucosae, is a rare complication of hematologic malignancy. Serologically, serum autoantibodies against varied desmosome-related proteins are of notice. PNP is often lethal due to bronchiolitis obliterans and opportunistic infection.
Kentaro Odani +6 more
openaire +3 more sources
Development of Acellular Respiratory Mucosal Matrix Using Porcine Tracheal Mucosa
Background: Respiratory mucosa defects result in airway obstruction and infection, requiring subsequent functional recovery of the respiratory epithelium.
김한수, 정수연, 최은오
core +1 more source
Human airway xenograft models of epithelial cell regeneration [PDF]
Regeneration and restoration of the airway epithelium after mechanical, viral or bacterial injury have a determinant role in the evolution of numerous respiratory diseases such as chronic bronchitis, asthma and cystic fibrosis.
Puchelle Edith +5 more
core +1 more source
Pseudomonas aeruginosa adhesion to normal and injured respiratory mucosa
Human nasal polyps outgrowth culture were used to study the adhesion of Pseudomonas aeruginosa to respiratory cells. By transmission electron microscopy, bacteria associated with ciliated cells were identified trapped at the extremities of cilia, usually
M. C. Plotkowski +3 more
doaj +1 more source
Oral Mucosa as a Potential Site for Diagnosis and Treatment of Allergic and Autoimmune Diseases
Most prevalent food allergies during early childhood are caused by foods with a high allergenic protein content, such as milk, egg, nuts, or fish. In older subjects, some respiratory allergies progressively lead to food-induced allergic reactions, which ...
Cristina Gomez-Casado +5 more
doaj +1 more source
Effects of Cigarette Smoke on the Nasal Respiratory and Olfactory Mucosa in Allergic Rhinitis Mice
ObjectiveCigarette smoke (CS) exposure reportedly enhances allergic airway inflammation. However, some studies have shown an association between current cigarette smoke exposure and a low risk for allergic rhinitis.
Rumi Ueha +4 more
doaj +1 more source
Histochemical and lectinhistochemical studies on nasal mucosa of pigs with or without respiratory diseases [PDF]
Histochemical and lectinhistochemical examinations were carried out on nasal mucosa of pigs with or without respiratory diseases. As the results, both acid and neutral mucins coexisted in nasal mucosa of normal pigs while acid sialomucins were mainly ...
Itagaki, Shin-ichi +5 more
core +2 more sources
In the modern world, allergic respiratory diseases hold a huge place among all chronic diseases. The annual increase in the prevalence of allergic rhinitis and bronchial asthma among the global population makes relevant studies underlying their ...
Anna M. Lazareva +2 more
doaj +1 more source

