Results 1 to 10 of about 126,031 (293)

The Development of a Human Respiratory Mucosa-on-a-Chip Using Human Turbinate-Derived Mesenchymal Stem Cells [PDF]

Medicina
Background and Objectives: This study aimed to investigate the influence of a respiratory mucosa-on-a-chip on the respiratory epithelial differentiation potential of human nasal inferior turbinate-derived stem cells (hNTSCs). Materials and Methods: After
Do Hyun Kim, Sang Hi Park, Mi-Yeon Kwon, Chae-Yoon Lim, Sun Hwa Park, David W. Jang, Se Hwan Hwang, Sung Won Kim   +7 more
doaj   +3 more sources

Bioengineering Human Upper Respiratory Mucosa: A Systematic Review of the State of the Art of Cell Culture Techniques [PDF]

Bioengineering
Background: The upper respiratory mucosa plays a crucial role in both the physical integrity and immunological function of the respiratory tract. However, in certain situations such as infections, trauma, or surgery, it might sustain damage.
Davaine Joel Ndongo Sonfack, Clémence Tanguay Boivin, Lydia Touzel Deschênes, Thibault Maurand, Célina Maguemoun, François Berthod, François Gros-Louis, Pierre-Olivier Champagne   +7 more
doaj   +3 more sources

Comparative analysis of replication characteristics of BoHV-1 subtypes in bovine respiratory and genital mucosa explants: a phylogenetic enlightenment [PDF]

Veterinary Research, 2011
In general, members of the Alphaherpesvirinae use the epithelium of the upper respiratory and/or genital tract as a preferential site for primary replication.
Steukers Lennert, Vandekerckhove Annelies P, Van den Broeck Wim, Glorieux Sarah, Nauwynck Hans J   +4 more
doaj   +4 more sources

IgA polymerization contributes to efficient virus neutralization on human upper respiratory mucosa after intranasal inactivated influenza vaccine administration [PDF]

Human Vaccines & Immunotherapeutics, 2018
Unlike the current injectable influenza vaccines, intranasally administered influenza vaccines induce influenza virus-specific IgA antibodies in the local respiratory mucosa as well as IgG antibodies in the systemic circulation. Our previous study showed
Yoshihiko Terauchi, Kaori Sano, Akira Ainai, Shinji Saito, Yuki Taga, Kiyoko Ogawa-Goto, Shin-ichi Tamura, Takato Odagiri, Masato Tashiro, Mikiya Fujieda, Tadaki Suzuki, Hideki Hasegawa   +11 more
doaj   +3 more sources

Identification of urban particulate matter-induced disruption of human respiratory mucosa integrity using whole transcriptome analysis and organ-on-a chip [PDF]

Journal of Biological Engineering, 2019
Background Exposure to air particulate matter (PM) is associated with various diseases in the human respiratory system. To date, most in vitro studies showing cellular responses to PM have been performed in cell culture using a single cell type.
Junhyoung Byun, Boa Song, Kyungwoo Lee, Byoungjae Kim, Hae Won Hwang, Myung-Ryul Ok, Hojeong Jeon, Kijeong Lee, Seung-Kuk Baek, Sang-Heon Kim, Seung Ja Oh, Tae Hoon Kim   +11 more
doaj   +2 more sources

Histological changes of conjunctiva-associated lymphoid tissue caused by pneumonia in Holstein young cows [PDF]

Veterinary and Animal Science
Conjunctiva-associated lymphoid tissue (CALT) induces mucosal IgA production on the ocular surface and within the respiratory mucosa. Increased CALTs have been reported in cows. The conjunctiva represents a potential site for mucosal vaccinations against
Keigo Kosenda, Yuki Ishiguro, Yuto Sano, Kazuya Matsuda, Tomochika Sugiura, Takashi Murakami, Ayano Sato, Hiromichi Ohtsuka, Shigeo Fukuda, Yasuhiro Kon, Takashi Namba, Osamu Ichii   +11 more
doaj   +2 more sources

The Respiratory Mucosa: Front and Center in Respiratory Syncytial Virus Disease. [PDF]

Am J Respir Crit Care Med, 2019
Thwaites RS, Openshaw PJ.
europepmc   +3 more sources

IRE1β evolves to be a guardian of respiratory and gastrointestinal mucosa

Heliyon
Inositol-requiring enzyme 1 (IRE1), a mediator of the unfolded protein response, shows the highest degree of evolutionary conservation. Vertebrates express two IRE1 paralogs: IRE1α, which is universally expressed and IRE1β, which shows specific ...
Hui Luo, Wen-Yan Gong, Yuan-Yuan Zhang, Ying-Ying Liu, Zhen Chen, Xing-Lin Feng, Qi-Bin Jiao, Xing-Wei Zhang   +7 more
doaj   +3 more sources

The Safety of Topical and Intravenous Tranexamic Acid in Endoscopic Sinus Surgery

Sinusitis, 2022
Tranexamic acid (TXA) is an inexpensive and widely used medication indicated for the reduction of bleeding. There are data showing the efficacy of intravenous (IV) and topical TXA in endoscopic sinus surgery (ESS) but the safety of this practice is not ...
Agrani Ratnayake Kumar, Andrew James Wood   +1 more
doaj   +1 more source

Mucosal Immune Responses to Respiratory Syncytial Virus

Cells, 2022
Despite over half a century of research, respiratory syncytial virus (RSV)-induced bronchiolitis remains a major cause of hospitalisation in infancy, while vaccines and specific therapies still await development.
Megan V. C. Barnes, Peter J. M. Openshaw, Ryan S. Thwaites   +2 more
doaj   +1 more source