Results 71 to 80 of about 194,896 (346)
ABSTRACT Background Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) is characterized by persistent sinonasal inflammation and marked eosinophilic infiltration. Although the relationship between eosinophils and NP formation has been extensively studied, the mechanisms governing eosinophil transepithelial migration into the nasal mucosa ...
Yeong‐In Jo +7 more
wiley +1 more source
RSV infection and recurrence of respiratory tract obstruction in children
Viruses, including the respiratory syncytial virus, are the most common aetiological factor of respiratory infections in children. The disease most often occurs between November and April in the northern climate zone, with a peak incidence in January ...
Karolina Kapusta +2 more
doaj +1 more source
PCR201 Estimating the Respiratory Syncytial Virus (RSV) Health Utility Values for Older Adults and Their Caregivers in the Japanese Population: A Time Trade-Off (TTO) Study [PDF]
Regina Rendas‐Baum +7 more
openalex +1 more source
Emergence and re-emergence of respiratory virus infections represent a significant threat to global public health, as they occur seasonally and less frequently (such as in the case of influenza virus) as pandemic infections.
M. A. Behzadi, V. Leyva-Grado
semanticscholar +1 more source
Viral etiology of the acute infections of the lower respiratory tract in Cuba
Background: acute respiratory infections are the main cause of mortality and morbidity worldwide, with respiratory viruses as main causative agents. Objective: to determine the paper of different respiratory viruses in the etiology of the severe acute ...
Aned Gordillo Hernández +2 more
doaj
Chronic lung disease predisposes to serious consequences of respiratory viruses. While increasing influenza immunization rates in older adults signals an awareness of the impact of influenza, children with asthma are infrequently immunized. While respiratory syncytial virus (RSV) is recognized as an important target of vaccine development for infants ...
Marie R, Griffin +5 more
openaire +2 more sources
Innate Immune Evasion by Human Respiratory RNA Viruses
The impact of respiratory virus infections on the health of children and adults can be very significant. Yet, in contrast to most other childhood infections as well as other viral and bacterial diseases, prophylactic vaccines or effective antiviral ...
M. Kikkert
semanticscholar +1 more source
While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart +7 more
wiley +1 more source
Population Pharmacokinetics of Clesrovimab in Preterm and Full‐Term Infants
Clesrovimab is a half‐life extended monoclonal antibody targeting the respiratory syncytial virus fusion protein. Three studies (phase Ib/IIa [MK‐1654‐002], phase IIb/III [CLEVER], and phase III [SMART]) were conducted to evaluate the efficacy, safety, and pharmacokinetics (PK) of clesrovimab in infants.
Ziheng Hu +8 more
wiley +1 more source
Acute lower respiratory tract infections are the leading cause of global morbidity and mortality in children under five years. Verification of the etiology of acute lower respiratory tract infections is necessary for definition of treatment and direction
A. V. Bogdanova +3 more
doaj

