Results 111 to 120 of about 24,845,891 (383)

COVID-19 pneumonia: different respiratory treatments for different phenotypes?

Intensive Care Medicine, 2020
The Surviving Sepsis Campaign panel recently recom-mended that “mechanically ventilated patients with COVID-19 should be managed similarly to other patients with acute respiratory failure in the ICU [1].” Yet, COVID-19 pneumonia [2], despite falling in ...
L. Gattinoni, D. Chiumello, P. Caironi, M. Busana, F. Romitti, L. Brazzi, L. Camporota   +6 more
semanticscholar   +1 more source

Characterization of the thermophilic xylanase Fsa02490Xyn from the hyperthermophile Fervidibacter sacchari belonging to glycoside hydrolase family 10

FEBS Open Bio, EarlyView.
Fervidibacter sacchari is a member of the bacterial phylum Armatimonadota, only a few of which have been cultivated. It is a hyperthermophilic polysaccharide degradation specialist. We show that a secreted enzyme, Fsa02490Xyn, is an endoxylanase belonging to glycoside hydrolase family 10.
Nicole Torosian, Jonathan K. Covington, Allison M. Cook, Nancy O. Nou, Marike Palmer, Ritesh Mewalal, Miranda Harmon‐Smith, Ian K. Blaby, Jan‐Fang Cheng, Matthias Hess, Brian P. Hedlund   +10 more
wiley   +1 more source

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

FEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash, Campbell W. Gourlay, Ina Oehme, Michelle D. Garrett, Jindrich Cinatl Jr, Mark N. Wass, Martin Michaelis   +6 more
wiley   +1 more source

Bacterial respiratory infection epidemiology and antibiogram profile in patients attending in regional hospital, Meknes, Morocco [PDF]

Microbes and Infectious Diseases
Objective: The main goal of this current study was to assess the prevalence of these infections in the outpatient setting as well as in hospitalized patients at Mohammed V Hospital in Meknes, Morocco.
Najia El Hamzaoui, Fatima El Kamari, Anjoud Harmouzi, Samira Jaouhar   +3 more
doaj   +1 more source

Anatomy and physiology of respiratory system relevant to anaesthesia

Indian Journal of Anaesthesia, 2015
Clinical application of anatomical and physiological knowledge of respiratory system improves patient's safety during anaesthesia. It also optimises patient's ventilatory condition and airway patency.
Apeksh Patwa, A. Shah
semanticscholar   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

FEATURES OF THE OUTBREAK OF THE COMMUNITY-ACQUIRED PNEUMONIA CAUSED BY MYCOPLASMA PNEUMOINIAE AT CHILDREN IN KHABAROVSK REGION

Журнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. To study the features of outbreak of community-acquired pneumonia caused by M. pneumoniae in children in the Khabarovsk region during the autumn-winter period 2016 - 2017. Materials and methods.
O. E. Guseva, O. A. Lebedko, E. B. Nagovitsyna, M. N. Lazutkin, E. A. Savitskaya, S. V. Klyueva, O. V. Putilina   +6 more
doaj   +1 more source

Aging of the respiratory system

, 2016
Changes in the respiratory system caused by aging generally include structural changes in the thoracic cage and lung parenchyma, abnormal findings on lung function tests, ventilation and gas exchange abnormalities, decreased exercise capacity, and ...
Seung Hun Lee, Su-Jin Yim, H. Kim
semanticscholar   +1 more source

NMR screening of low molecular weight inhibitors targeting the papain‐like protease (PLPro) of SARS‐CoV‐2

FEBS Open Bio, EarlyView.
Papain‐like protease from SARS‐CoV‐2 plays an important role in the cleavage of the viral polyproteins and in the suppression of the host's immune response. Here, we present the results of an NMR screening study. We identified 86 binding compounds, of which five candidates were chosen for in‐depth analysis.
Dennis J. Pyper, Sridhar Sreeramulu, Benjamin T. Lanham, Elizabeth M. Engle, David Fushman, Harald Schwalbe   +5 more
wiley   +1 more source

Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?

Viruses, 2019
Respiratory viruses infect the human upper respiratory tract, mostly causing mild diseases. However, in vulnerable populations, such as newborns, infants, the elderly and immune-compromised individuals, these opportunistic pathogens can also affect the ...
M. Desforges, Alain Le Coupanec, Philippe Dubeau, Andréanne Bourgouin, L. Lajoie, M. Dubé, P. Talbot   +6 more
semanticscholar   +1 more source