Results 131 to 140 of about 24,845,891 (383)
In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock +8 more
wiley +1 more source
Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó +17 more
wiley +1 more source
Modeling of Respiratory System [PDF]
, 2008 Tato práce se zabývá simulací dýchací soustavy. Cílem studie je porozumění dýchací soustavy lidského organismu, společně s volbou vhodných algoritmů a jejich následnou implementací do matematického modelu.
Matoušek, Josef
core
Cerebral and Peripheral Tissue Oxygenation in Children Supported on ECMO for Cardio-Respiratory Failure [PDF]
, 2009 Extracorporeal membrane oxygenation (ECMO) is a rescue therapy for patients with cardio-respiratory failure. Establishing, maintaining and weaning from ECMO may increase the risk for intracranial injury.
Elliott, MJ +5 more
core +1 more source
Tasmania Araneae of the family Hahniidae with notes on their respiratory systems [PDF]
, 1947 VV Hickman
openalex +1 more source
The transport and deposition of nanoparticles in respiratory system by inhalation
, 2015 The inhaled nanoparticles have attracted more and more attention, since they are more easily to enter the deep part of respiratory system. Some nanoparticles were reported to cause pulmonary inflammation. The toxicity of nanoparticles depends not only on
Huiting Qiao +4 more
semanticscholar +1 more source
NOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by NOTCH2NLC GGC repeat expansions, with heterogeneous clinical manifestations, including parkinsonism. Recent studies have identified NOTCH2NLC repeat expansions in patients with Parkinson's disease (PD) and atypical parkinsonism (aPM), suggesting ...
Han‐Lin Chiang +7 more
wiley +1 more source
Respiratory protective device design using control system techniques [PDF]
The feasibility of a control system analysis approach to provide a design base for respiratory protective devices is considered. A system design approach requires that all functions and components of the system be mathematically identified in a model of ...
Burgess, W. A., Yankovich, D.
core +1 more source