Results 21 to 30 of about 713,137 (254)

Randomized Double-Blind Trial of the Effects of Humidified Compared with Nonhumidified Low Flow Oxygen Therapy on the Symptoms of Patients

Canadian Respiratory Journal, 1997
OBJECTIVE: To determine the effects of humidified versus nonhumidified low flow oxygen therapy on the subjective symptoms of patients.
Darcy Andres, Norma Thurston, Rollin Brant, Ward Flemons, Doreen Fofonoff, Ardis Ruttimann, Sandra Sveinson, Carol Neil   +7 more
doaj   +1 more source

FJU‐C28 inhibits the endotoxin‐induced pro‐inflammatory cytokines expression via suppressing JNK, p38 MAPK and NF‐κB signaling pathways

Pharmacology Research & Perspectives, 2021
Despite marked improvements in supportive care, the mortality rate of acute respiratory distress syndrome due to the excessive inflammatory response caused by direct or indirect lung injury induced by viral or bacterial infection is still high.
Fang Jung, Jung‐Sen Liu, Shih‐Hsing Yang, Hui‐Yun Tseng, Shang‐Shing P. Chou, Jau‐Chen Lin, Guey‐Mei Jow   +6 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Awareness and practice of airway pressure release ventilation mode in acute respiratory distress syndrome patients among nurses in Saudi Arabia

BMC Nursing
Background This study aimed to assess the knowledge and current practice of using the airway pressure release ventilation (APRV) mode with acute respiratory distress syndrome (ARDS) patients and identify barriers to not using this mode of ventilation ...
Abdulelah M. Aldhahir, Abdullah A. Alqarni, Mohammed A. Madkhali, Hussain H. Madkhali, Abdullah A. Bakri, Mohammad A. Shawany, Ahmed H. Alasimi, Abdullah S. Alsulayyim, Jaber S. Alqahtani, Mohammed M. Alyami, Saeed M. Alghamdi, Omar A. Alqarni, Ali Hakamy   +12 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Clinical practices, self-confidence, and perceived barriers in tracheostomy care among respiratory therapists in Saudi Arabia: a national cross-sectional study

BMC Medical Education
Background Tracheostomy care is a critical aspect of respiratory therapy, requiring specialized knowledge and adherence to standardized protocols to ensure optimal patient outcomes.
Abdulelah M. Aldhahir, Ahmed H. Alasimi, Yunus A. Jothmi, Muhannad N. Khowaji, Abdullah A. Najaei, Jehad M. Rayyani, Ammar N. Alwadani, Abdullah A. Alqarni, Jaber S. Alqahtani, Rayan A. Siraj, Munyra Alhotye, Mohammed A. Reyany, Mohamed H. Hakamy, Mohammad A. Shawany, Ali Hakamy   +14 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The impact of aerosolized mucolytic agents on the airflow resistance of bacterial filters used in mechanical ventilation

Journal of the Formosan Medical Association, 2015
In order to reduce the contamination in the ventilator, bacterial filters were placed on the expiratory limb of a ventilator circuit. Aerosolized mucolytic agents may increase the resistance of the ventilator.
Han-Chung Hu, Hsin-Chun Liu, Yen-Huey Chen, Chung-Chi Huang, Gwo-Hwa Wan, Lan-Ti Chou, Meng-Jer Hsieh, Ning-Hung Chen, Cheng-Ta Yang, Kuo-Chin Kao   +9 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Virtual pulmonary rehabilitation approaches in patients with post COVID syndrome: a pilot study

BMC Pulmonary Medicine
Background The characteristics of optimal virtual pulmonary rehabilitation (PR) for individuals with post-COVID syndrome (PCS) have not been identified.
Antonio Sarmento, Rachel Adodo, Greg Hodges, Sandra C. Webber, Diana C. Sanchez-Ramirez   +4 more
doaj   +1 more source