Results 41 to 50 of about 1,201,684 (350)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Randomized Double-Blind Trial of the Effects of Humidified Compared with Nonhumidified Low Flow Oxygen Therapy on the Symptoms of Patients

Canadian Respiratory Journal, 1997
OBJECTIVE: To determine the effects of humidified versus nonhumidified low flow oxygen therapy on the subjective symptoms of patients.
Darcy Andres, Norma Thurston, Rollin Brant, Ward Flemons, Doreen Fofonoff, Ardis Ruttimann, Sandra Sveinson, Carol Neil   +7 more
doaj   +1 more source

Traditional Chinese Medicine Enema Therapy in a Patient With a Confirmed Negative SARS-CoV-2 Test in the Respiratory Tract but Positive in the Intestinal Tract: A Case Report [PDF]

, 2021
Yuzhu Dai, Zhiyou Zhao, Huajun Zhou, Dedong Huang, Jianjun Luo, Cunhai Zhang, Qingyong Chen, Xingcan Chen, Yuan Yao, Xiaoxiao Jiang, Jun Cheng   +10 more
openalex   +1 more source

The Role of rescue therapies in the treatment of severe ARDS [PDF]

, 2018
ARDS is characterized by a non-cardiogenic pulmonary edema with bilateral chest radiograph opacities and hypoxemia refractory to oxygen therapy. It is a common cause of admission to the ICU due to hypoxemic respiratory failure requiring mechanical ...
Alessandri, F, Pugliese, F, Ranieri, M.
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Drug Concentrations in the Air and their Influencing Factors in a Pediatric Intensive Care Unit

Aerosol and Air Quality Research
Aerosolized drug therapy is a common approach in treating respiratory diseases in clinical practice. This study aimed to assess air quality in the pediatric intensive care unit (PICU) of the medical center and investigate variations in drug concentration
Hui-Yun Tseng, Yi-Ting Tsai, Ying-Shiuan Su, Po-Pei Peng, Gwo-Hwa Wan   +4 more
doaj   +1 more source

FJU‐C28 inhibits the endotoxin‐induced pro‐inflammatory cytokines expression via suppressing JNK, p38 MAPK and NF‐κB signaling pathways

Pharmacology Research & Perspectives, 2021
Despite marked improvements in supportive care, the mortality rate of acute respiratory distress syndrome due to the excessive inflammatory response caused by direct or indirect lung injury induced by viral or bacterial infection is still high.
Fang Jung, Jung‐Sen Liu, Shih‐Hsing Yang, Hui‐Yun Tseng, Shang‐Shing P. Chou, Jau‐Chen Lin, Guey‐Mei Jow   +6 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Awareness and practice of airway pressure release ventilation mode in acute respiratory distress syndrome patients among nurses in Saudi Arabia

BMC Nursing
Background This study aimed to assess the knowledge and current practice of using the airway pressure release ventilation (APRV) mode with acute respiratory distress syndrome (ARDS) patients and identify barriers to not using this mode of ventilation ...
Abdulelah M. Aldhahir, Abdullah A. Alqarni, Mohammed A. Madkhali, Hussain H. Madkhali, Abdullah A. Bakri, Mohammad A. Shawany, Ahmed H. Alasimi, Abdullah S. Alsulayyim, Jaber S. Alqahtani, Mohammed M. Alyami, Saeed M. Alghamdi, Omar A. Alqarni, Ali Hakamy   +12 more
doaj   +1 more source

Specific features of antimicrobial therapy in patients with severe respiratory failure receiving veno-venous extracorporeal membrane oxygenation (ECMO) [PDF]

, 2023
M. А. Petrushin, P.I. Melnichenko, П А Власов, I. S. Nikiforov, Elena Kudryashova, I.A. Glushchenko   +5 more
openalex   +1 more source